CRCGN015_HEPG2_48H:K10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description wortmannin 10.0 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

863 genes differentially expressed following the CRCGN015_HEPG2_48H:K10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 4.63455
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.76681
TLN2 talin 2 3.68737
TBC1D17 TBC1 domain family, member 17 3.63862
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.62086
NHERF4 NHERF family PDZ scaffold protein 4 3.60255
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.57088
RAB40C RAB40C, member RAS oncogene family 3.53208
HPX hemopexin 3.53016
FAM111A family with sequence similarity 111, member A 3.44367
GPR27 G protein-coupled receptor 27 3.41977
CFAP69 cilia and flagella associated protein 69 3.3772
TMPRSS6 transmembrane protease, serine 6 3.30694
UPB1 ureidopropionase, beta 3.29546
PLG plasminogen 3.26767
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 3.26475
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 3.24272
QTRT1 queuine tRNA-ribosyltransferase 1 3.22708
FANCG Fanconi anemia, complementation group G 3.2121
GSTK1 glutathione S-transferase kappa 1 3.1712
DNAL4 dynein, axonemal, light chain 4 3.15383
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 3.11365
ADGRB1 adhesion G protein-coupled receptor B1 3.10823
PRKCG protein kinase C, gamma 3.10066
PHF13 PHD finger protein 13 3.09524
MYO1F myosin IF 3.0819
PAOX polyamine oxidase (exo-N4-amino) 3.07975
CBX7 chromobox homolog 7 3.07752
DPYS dihydropyrimidinase 3.05957
PICK1 protein interacting with PRKCA 1 3.0542
DTX4 deltex 4, E3 ubiquitin ligase 3.04752
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 3.03411
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 3.02773
FRRS1L ferric-chelate reductase 1-like 3.00853
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 2.99831
MAP2K5 mitogen-activated protein kinase kinase 5 2.99684
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 2.97673
TCEA2 transcription elongation factor A (SII), 2 2.94647
CIAO3 cytosolic iron-sulfur assembly component 3 2.94087
SLC38A4 solute carrier family 38, member 4 2.94049
ICAM3 intercellular adhesion molecule 3 2.92432
BRME1 break repair meiotic recombinase recruitment factor 1 2.92325
CABP1 calcium binding protein 1 2.91937
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.91913
HSF4 heat shock transcription factor 4 2.87424
ABHD4 abhydrolase domain containing 4 2.87343
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.86388
MOGAT3 monoacylglycerol O-acyltransferase 3 2.8574
SLC17A4 solute carrier family 17, member 4 2.85714
NEUROD6 neuronal differentiation 6 2.85542
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2.84875
RLN2 relaxin 2 2.83386
PNMA3 paraneoplastic Ma antigen 3 2.83137
UBA7 ubiquitin-like modifier activating enzyme 7 2.82741
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.82235
LOC107987479 cytochrome P450 2D6 2.82179
NPAS1 neuronal PAS domain protein 1 2.81906
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.80993
GRAMD1C GRAM domain containing 1C 2.80885
NCF1 neutrophil cytosolic factor 1 2.80268
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 2.79079
BTBD8 BTB (POZ) domain containing 8 2.78582
AVIL advillin 2.77897
ETV2 ets variant 2 2.77277
APOL3 apolipoprotein L, 3 2.76455
SEPTIN5 septin 5 2.76389
ITM2B integral membrane protein 2B 2.75909
FUZ fuzzy planar cell polarity protein 2.75771
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.75621
NDRG1 N-myc downstream regulated 1 2.74824
JPH3 junctophilin 3 2.74761
AFM afamin 2.74663
NRGN neurogranin (protein kinase C substrate, RC3) 2.74513
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.73819
ACO2 aconitase 2, mitochondrial 2.73444
DGCR2 DiGeorge syndrome critical region gene 2 2.72825
ING4 inhibitor of growth family, member 4 2.72763
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 2.72323
GPRIN1 G protein regulated inducer of neurite outgrowth 1 2.72167
GRM2 glutamate receptor, metabotropic 2 2.71767
MMP17 matrix metallopeptidase 17 (membrane-inserted) 2.69858
MAPK4 mitogen-activated protein kinase 4 2.69697
APOBR apolipoprotein B receptor 2.69588
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.6882
ZNF688 zinc finger protein 688 2.68666
PLCH2 phospholipase C, eta 2 2.68569
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.68414
PFKM phosphofructokinase, muscle 2.68357
RDH16 retinol dehydrogenase 16 (all-trans) 2.67858
PRKX protein kinase, X-linked 2.67754
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.67714
VNN1 vanin 1 2.676
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.67317
CDC50B cell division cycle 50 P4-ATPase accessory subunit B 2.66554
ATRNL1 attractin-like 1 2.66376
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.6539
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.6524
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.65136
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.65124
ATRIP ATR interacting protein 2.64738
FANCE Fanconi anemia, complementation group E 2.64618
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.64423
DGKB diacylglycerol kinase, beta 90kDa 2.64093
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.63986
ETFDH electron-transferring-flavoprotein dehydrogenase 2.63275
ACSM2A acyl-CoA synthetase medium-chain family member 2A 2.63075
GHRH growth hormone releasing hormone 2.62827
SGSM3 small G protein signaling modulator 3 2.62562
NCKIPSD NCK interacting protein with SH3 domain 2.61929
MOCS1 molybdenum cofactor synthesis 1 2.61514
ZFTRAF1 zinc finger TRAF-type containing 1 2.61484
ANGPTL3 angiopoietin-like 3 2.61153
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.61043
CDK18 cyclin-dependent kinase 18 2.60676
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.59977
PRSS16 protease, serine, 16 (thymus) 2.59793
GFI1B growth factor independent 1B transcription repressor 2.59652
IMPACT impact RWD domain protein 2.59616
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.5934
VTN vitronectin 2.5933
HSFX2 heat shock transcription factor family, X linked 2 2.59302
CFHR3 complement factor H-related 3 2.58726
CFHR2 complement factor H-related 2 2.58599
GNRH2 gonadotropin-releasing hormone 2 2.58385
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.58104
NMUR1 neuromedin U receptor 1 2.5736
PTGDR2 prostaglandin D2 receptor 2 2.57256
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.56606
GDF2 growth differentiation factor 2 2.56235
VIPR1 vasoactive intestinal peptide receptor 1 2.56229
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.55758
A4GALT alpha 1,4-galactosyltransferase 2.55593
CDK5 cyclin-dependent kinase 5 2.55409
CDK20 cyclin-dependent kinase 20 2.5532
KDM8 lysine (K)-specific demethylase 8 2.5513
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.55109
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.54761
PAX3 paired box 3 2.54365
HAO2 hydroxyacid oxidase 2 (long chain) 2.54281
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 2.5397
PRODH proline dehydrogenase (oxidase) 1 2.53627
TMEM59L transmembrane protein 59-like 2.53594
SNX7 sorting nexin 7 2.53588
MPPED1 metallophosphoesterase domain containing 1 2.53448
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.5327
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.52922
NELL2 NEL-like 2 (chicken) 2.52794
LETMD1 LETM1 domain containing 1 2.52641
GRAP2 GRB2-related adaptor protein 2 2.52405
CCDC106 coiled-coil domain containing 106 2.52346
NPFFR1 neuropeptide FF receptor 1 2.52262
GRAPL GRB2-related adaptor protein-like 2.52126
KCNIP2 Kv channel interacting protein 2 2.51531
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.51451
CCNP cyclin P 2.51279
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.51093
IL7 interleukin 7 2.5076
CRYM crystallin, mu 2.50738
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.49464
TREX2 three prime repair exonuclease 2 2.49435
ICAM5 intercellular adhesion molecule 5, telencephalin 2.48218
ITFG1 integrin alpha FG-GAP repeat containing 1 2.48157
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.48114
CAMKV CaM kinase-like vesicle-associated 2.47845
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.47362
GYS2 glycogen synthase 2 (liver) 2.47309
C8G complement component 8, gamma polypeptide 2.46924
SNPH syntaphilin 2.46354
REEP2 receptor accessory protein 2 2.45437
ACAD10 acyl-CoA dehydrogenase family, member 10 2.45197
TTLL1 tubulin tyrosine ligase-like family member 1 2.45149
PRDM12 PR domain containing 12 2.45147
ZBTB7B zinc finger and BTB domain containing 7B 2.4513
SNTA1 syntrophin, alpha 1 2.45026
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.44735
RARG retinoic acid receptor, gamma 2.44566
SH3GL2 SH3-domain GRB2-like 2 2.4453
ATOH1 atonal homolog 1 (Drosophila) 2.44434
DOCK3 dedicator of cytokinesis 3 2.43953
FETUB fetuin B 2.43881
DOC2A double C2-like domains, alpha 2.4355
CUX2 cut-like homeobox 2 2.43523
MXD3 MAX dimerization protein 3 2.43425
DOC2B double C2-like domains, beta 2.43411
RLBP1 retinaldehyde binding protein 1 2.43334
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.43105
ADAP1 ArfGAP with dual PH domains 1 2.43065
LMF2 lipase maturation factor 2 2.42775
SV2A synaptic vesicle glycoprotein 2A 2.4159
CIDEB cell death-inducing DFFA-like effector b 2.41515
BSN bassoon presynaptic cytomatrix protein 2.41511
RGS14 regulator of G-protein signaling 14 2.41294
FSD1 fibronectin type III and SPRY domain containing 1 2.41077
EML2 echinoderm microtubule associated protein like 2 2.40997
CYTH4 cytohesin 4 2.40828
GCC2 GRIP and coiled-coil domain containing 2 2.40503
IPO13 importin 13 2.40003
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.39975
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.3965
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.39457
FAIM2 Fas apoptotic inhibitory molecule 2 2.39289
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.39271
CAPN1 calpain 1, (mu/I) large subunit 2.39063
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 2.38982
FLT3LG fms-related tyrosine kinase 3 ligand 2.38982
NCAPH2 non-SMC condensin II complex, subunit H2 2.3887
CNPY3-GNMT CNPY3-GNMT readthrough 2.38732
GP9 glycoprotein IX (platelet) 2.38369
HEMK1 HemK methyltransferase family member 1 2.38284
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.38269
AMDHD2 amidohydrolase domain containing 2 2.38145
SOD3 superoxide dismutase 3, extracellular 2.3804
DDTL D-dopachrome tautomerase-like 2.38005
RGL4 ral guanine nucleotide dissociation stimulator-like 4 2.37945
RASA3 RAS p21 protein activator 3 2.37844
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.37522
TBXA2R thromboxane A2 receptor 2.37455
FTCD formimidoyltransferase cyclodeaminase 2.37319
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 2.3729
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.37285
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.37282
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.37013
ONECUT1 one cut homeobox 1 2.36535
DDO D-aspartate oxidase 2.36488
CDK10 cyclin-dependent kinase 10 2.36421
PCLO piccolo presynaptic cytomatrix protein 2.36347
HHLA1 HERV-H LTR-associating 1 2.36087
WNT11 wingless-type MMTV integration site family, member 11 2.3575
F13B coagulation factor XIII, B polypeptide 2.35619
INPP5J inositol polyphosphate-5-phosphatase J 2.3549
CRBN cereblon 2.35318
DLX5 distal-less homeobox 5 2.3515
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.35108
PRODH2 proline dehydrogenase (oxidase) 2 2.35022
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 2.34888
LDAF1 lipid droplet assembly factor 1 2.34878
IFT140 intraflagellar transport 140 2.34868
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.34578
CPTP ceramide-1-phosphate transfer protein 2.3454
SLC22A17 solute carrier family 22, member 17 2.34486
PMM1 phosphomannomutase 1 2.34481
HOXA3 homeobox A3 2.34477
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.34443
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.34389
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.34385
RAX retina and anterior neural fold homeobox 2.3411
COL5A3 collagen, type V, alpha 3 2.3411
GTF2IRD2B GTF2I repeat domain containing 2B 2.33899
WNT5A wingless-type MMTV integration site family, member 5A 2.3374
IQSEC2 IQ motif and Sec7 domain 2 2.33566
CAPN11 calpain 11 2.33477
TCF20 transcription factor 20 (AR1) 2.33446
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.33368
CSRNP3 cysteine-serine-rich nuclear protein 3 2.33296
PEX6 peroxisomal biogenesis factor 6 2.32835
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 2.3281
SCN3B sodium channel, voltage gated, type III beta subunit 2.32621
PCDHA10 protocadherin alpha 10 2.32525
CREBL2 cAMP responsive element binding protein-like 2 2.32442
GSTA1 glutathione S-transferase alpha 1 2.32392
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.32292
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 2.32275
CABP2 calcium binding protein 2 2.32266
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.31963
GPR162 G protein-coupled receptor 162 2.31921
ENTREP2 endosomal transmembrane epsin interactor 2 2.31827
BTN3A1 butyrophilin, subfamily 3, member A1 2.31723
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 2.31632
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.31408
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.31366
BPHL biphenyl hydrolase-like (serine hydrolase) 2.31318
TREH trehalase (brush-border membrane glycoprotein) 2.31094
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.30886
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.30743
FOXL1 forkhead box L1 2.30665
NOP53 NOP53 ribosome biogenesis factor 2.30513
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.30501
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.30462
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 2.304
EXT1 exostosin glycosyltransferase 1 2.30334
MICALL2 MICAL-like 2 2.30334
RAB3A RAB3A, member RAS oncogene family 2.29919
ADM2 adrenomedullin 2 2.29854
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.29785
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 2.29703
LIN7B lin-7 homolog B (C. elegans) 2.29276
EPHA1 EPH receptor A1 2.29182
NMRK1 nicotinamide riboside kinase 1 2.29095
MEST mesoderm specific transcript 2.2893
SYNGR1 synaptogyrin 1 2.28905
PDZD7 PDZ domain containing 7 2.28865
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.28839
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.28809
CYB5RL cytochrome b5 reductase-like 2.28774
SNCB synuclein, beta 2.28482
SORBS1 sorbin and SH3 domain containing 1 2.28298
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.28249
KLHDC3 kelch domain containing 3 2.28216
C8B complement component 8, beta polypeptide 2.28164
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.28058
NRXN2 neurexin 2 2.27989
CATSPERH catsper channel auxiliary subunit eta 2.27913
EDN1 endothelin 1 2.27322
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.27161
TARBP1 TAR (HIV-1) RNA binding protein 1 2.2704
GAL3ST1 galactose-3-O-sulfotransferase 1 2.27033
TRIM11 tripartite motif containing 11 2.27029
UNC13A unc-13 homolog A (C. elegans) 2.27012
LHX5 LIM homeobox 5 2.26957
CCDC81 coiled-coil domain containing 81 2.26951
EXPH5 exophilin 5 2.26837
PON3 paraoxonase 3 2.26781
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.26544
CHAD chondroadherin 2.26456
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.26297
AMHR2 anti-Mullerian hormone receptor, type II 2.26188
KIF25 kinesin family member 25 2.26182
STARD5 StAR-related lipid transfer (START) domain containing 5 2.25983
HPCA hippocalcin 2.25336
MUC3B mucin 3B, cell surface associated 2.25304
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.25236
LYRM9 LYR motif containing 9 2.25188
ZNF175 zinc finger protein 175 2.25135
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.25038
RAB17 RAB17, member RAS oncogene family 2.25026
CHD6 chromodomain helicase DNA binding protein 6 2.24923
F9 coagulation factor IX 2.24782
ACADL acyl-CoA dehydrogenase, long chain 2.24717
IZUMO4 IZUMO family member 4 2.24625
SNAP91 synaptosomal-associated protein, 91kDa 2.24504
ZNF623 zinc finger protein 623 2.24408
OSBP2 oxysterol binding protein 2 2.24398
ZBTB7C zinc finger and BTB domain containing 7C 2.23994
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.23909
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.23704
CDX4 caudal type homeobox 4 2.23367
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.23255
AQP7 aquaporin 7 2.2324
TEF thyrotrophic embryonic factor 2.23219
KCNK10 potassium channel, two pore domain subfamily K, member 10 2.2302
MEGF6 multiple EGF-like-domains 6 2.22901
CDK3 cyclin-dependent kinase 3 2.22865
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.22839
PRMT8 protein arginine methyltransferase 8 2.22716
SAMD14 sterile alpha motif domain containing 14 2.22648
ACSM5 acyl-CoA synthetase medium-chain family member 5 2.22539
AKAP5 A kinase (PRKA) anchor protein 5 2.2253
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.22367
TMEM184B transmembrane protein 184B 2.22164
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.22123
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.22114
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 2.22084
ERBB4 erb-b2 receptor tyrosine kinase 4 2.2195
JRK Jrk homolog (mouse) 2.21944
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.2184
CCHCR1 coiled-coil alpha-helical rod protein 1 2.2171
ITGB7 integrin, beta 7 2.21572
METTL17 methyltransferase like 17 2.21494
FGF21 fibroblast growth factor 21 2.2147
AVPR1B arginine vasopressin receptor 1B 2.21462
RLN1 relaxin 1 2.21413
DTX2 deltex 2, E3 ubiquitin ligase 2.21175
SH3YL1 SH3 and SYLF domain containing 1 2.21174
HSPB3 heat shock 27kDa protein 3 2.21152
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough 2.21097
COL5A2 collagen, type V, alpha 2 2.2098
NEURL1 neuralized E3 ubiquitin protein ligase 1 2.20848
LY6H lymphocyte antigen 6 complex, locus H 2.20684
C8A complement component 8, alpha polypeptide 2.20546
RAB36 RAB36, member RAS oncogene family 2.20542
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.20445
GRM5 glutamate receptor, metabotropic 5 2.20441
APCS amyloid P component, serum 2.20181
FOXH1 forkhead box H1 2.1999
GALT galactose-1-phosphate uridylyltransferase 2.19986
LRRTM4 leucine rich repeat transmembrane neuronal 4 2.19874
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.19716
PHF24 PHD finger protein 24 2.19705
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 2.19587
SPEF1 sperm flagellar 1 2.19461
GPAA1 glycosylphosphatidylinositol anchor attachment 1 2.19432
JPH2 junctophilin 2 2.1941
ALLC allantoicase 2.19321
OTC ornithine carbamoyltransferase 2.19195
NXPH3 neurexophilin 3 2.19183
TMEM106C transmembrane protein 106C 2.19086
KLHL1 kelch-like family member 1 2.19026
GPR37L1 G protein-coupled receptor 37 like 1 2.18937
LBX1 ladybird homeobox 1 2.18551
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.18503
BHMT betaine--homocysteine S-methyltransferase 2.18346
SPTBN2 spectrin, beta, non-erythrocytic 2 2.18307
UTF1 undifferentiated embryonic cell transcription factor 1 2.18268
GIPR gastric inhibitory polypeptide receptor 2.18208
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 2.18128
MAP3K7CL MAP3K7 C-terminal like 2.18001
SYT5 synaptotagmin V 2.17893
SYBU syntabulin (syntaxin-interacting) 2.17854
SLC35E2B solute carrier family 35, member E2B 2.17788
SGPP2 sphingosine-1-phosphate phosphatase 2 2.17759
SBF1 SET binding factor 1 2.17667
STAT2 signal transducer and activator of transcription 2, 113kDa 2.17666
TRO trophinin 2.17656
TUSC3 tumor suppressor candidate 3 2.17546
MAPK10 mitogen-activated protein kinase 10 2.17481
HOXA6 homeobox A6 2.17466
EPHX2 epoxide hydrolase 2, cytoplasmic 2.17463
LOC107986346 mitochondrial import receptor subunit TOM7 homolog 2.17216
NCR3 natural cytotoxicity triggering receptor 3 2.16926
PTK2B protein tyrosine kinase 2 beta 2.16902
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 2.16788
NCR2 natural cytotoxicity triggering receptor 2 2.16606
CCNA1 cyclin A1 2.16448
TMEM223 transmembrane protein 223 2.1612
TTC12 tetratricopeptide repeat domain 12 2.15928
SHBG sex hormone-binding globulin 2.15915
SYF2 SYF2 pre-mRNA-splicing factor 2.15901
CCL15 chemokine (C-C motif) ligand 15 2.15862
CD163L1 CD163 molecule-like 1 2.15846
SLC7A4 solute carrier family 7, member 4 2.15576
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.15446
GPR137 G protein-coupled receptor 137 2.15355
SNX10 sorting nexin 10 2.15292
BCL9 B-cell CLL/lymphoma 9 2.15284
TMEM35A transmembrane protein 35A 2.1522
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 2.15208
SOX10 SRY (sex determining region Y)-box 10 2.15177
EXTL1 exostosin-like glycosyltransferase 1 2.14913
PSENEN presenilin enhancer gamma secretase subunit 2.14888
ZFR2 zinc finger RNA binding protein 2 2.14828
MPST mercaptopyruvate sulfurtransferase 2.14818
FOXB1 forkhead box B1 2.14765
CD226 CD226 molecule 2.14498
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 2.14467
IL12RB1 interleukin 12 receptor, beta 1 2.14392
TESK1 testis-specific kinase 1 2.1434
UBQLN2 ubiquilin 2 2.1424
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 2.14132
PSPN persephin 2.14092
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 2.14069
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.14056
COL21A1 collagen, type XXI, alpha 1 2.13825
KIF17 kinesin family member 17 2.13805
CDHR5 cadherin-related family member 5 2.13787
AKR1C4 aldo-keto reductase family 1, member C4 2.13744
ALAS1 5'-aminolevulinate synthase 1 2.13726
FSHR follicle stimulating hormone receptor 2.13683
RIPOR2 RHO family interacting cell polarization regulator 2 2.13665
ADGRB2 adhesion G protein-coupled receptor B2 2.13662
PALM paralemmin 2.13616
SACK1E scaffolding CK1 anchoring protein E 2.13612
HROB homologous recombination factor with OB-fold 2.13601
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 2.13572
OXT oxytocin/neurophysin I prepropeptide 2.1347
WDR7 WD repeat domain 7 2.13457
IFT27 intraflagellar transport 27 2.13321
KIF22 kinesin family member 22 2.13233
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.12972
PNMA2 paraneoplastic Ma antigen 2 2.12877
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.12858
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 2.12674
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.12668
RORC RAR-related orphan receptor C 2.12531
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.12454
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.12409
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.12263
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 2.11986
PSD4 pleckstrin and Sec7 domain containing 4 2.11954
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.11934
ALX3 ALX homeobox 3 2.119
CTSA cathepsin A 2.11782
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.1156
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 2.1148
THBS3 thrombospondin 3 2.11295
KLK15 kallikrein-related peptidase 15 2.11206
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 2.10803
CUL9 cullin 9 2.10748
WDR19 WD repeat domain 19 2.10742
C1RL complement component 1, r subcomponent-like 2.10556
DGKI diacylglycerol kinase, iota 2.10526
ITGA7 integrin, alpha 7 2.10506
SLITRK2 SLIT and NTRK-like family, member 2 2.10448
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 2.10369
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.10367
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 2.10297
BAIAP3 BAI1-associated protein 3 2.10278
IQSEC1 IQ motif and Sec7 domain 1 2.10274
CTNNA2 catenin (cadherin-associated protein), alpha 2 2.10231
RPAP2 RNA polymerase II associated protein 2 2.10183
VENTX VENT homeobox 2.10153
DOK3 docking protein 3 2.09895
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.09792
MOB3B MOB kinase activator 3B 2.09716
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.09662
BIRC3 baculoviral IAP repeat containing 3 2.09609
PMVK phosphomevalonate kinase 2.09602
LMAN1L lectin, mannose-binding, 1 like 2.09521
SARM1 sterile alpha and TIR motif containing 1 2.0947
FRMPD4 FERM and PDZ domain containing 4 2.09434
DGKQ diacylglycerol kinase, theta 110kDa 2.09247
SUSD4 sushi domain containing 4 2.09149
NECTIN1 nectin cell adhesion molecule 1 2.09039
LGALS4 lectin, galactoside-binding, soluble, 4 2.09022
TRIM15 tripartite motif containing 15 2.08979
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.08953
THY1 Thy-1 cell surface antigen 2.08927
RFX1 regulatory factor X, 1 (influences HLA class II expression) 2.08911
GMEB1 glucocorticoid modulatory element binding protein 1 2.08752
MAG myelin associated glycoprotein 2.08643
KNG1 kininogen 1 2.08608
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.08522
POU6F2 POU class 6 homeobox 2 2.08481
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.08405
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.08396
CASD1 CAS1 domain containing 1 2.08313
KALRN kalirin, RhoGEF kinase 2.08199
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.07941
AMH anti-Mullerian hormone 2.07902
SIRPA signal-regulatory protein alpha 2.07866
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 2.0785
TTC21B tetratricopeptide repeat domain 21B 2.07833
RERGL RERG/RAS-like 2.07765
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.07719
YPEL1 yippee-like 1 (Drosophila) 2.07675
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.07604
SPTB spectrin, beta, erythrocytic 2.07599
TUBA3E tubulin, alpha 3e 2.07415
RNF170 ring finger protein 170 2.07389
TFR2 transferrin receptor 2 2.07308
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 2.07144
MORN1 MORN repeat containing 1 2.06863
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.06581
STK38 serine/threonine kinase 38 2.06532
TCEAL9 transcription elongation factor A like 9 2.06518
ADCY1 adenylate cyclase 1 (brain) 2.0644
METTL4 methyltransferase like 4 2.06439
KIF26B kinesin family member 26B 2.06351
EVX1 even-skipped homeobox 1 2.06261
HPR haptoglobin-related protein 2.0626
HACL2 2-hydroxyacyl-CoA lyase 2 2.06131
INSRR insulin receptor-related receptor 2.06121
MYH2 myosin, heavy chain 2, skeletal muscle, adult 2.06083
ARHGAP33 Rho GTPase activating protein 33 2.06038
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.06026
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.06025
GUCY2C guanylate cyclase 2C 2.05992
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.05971
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.05933
GPR17 G protein-coupled receptor 17 2.05922
CALCOCO1 calcium binding and coiled-coil domain 1 2.0592
REX1BD required for excision 1-B domain containing 2.05868
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.05821
HPN hepsin 2.05424
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.05313
GLCE glucuronic acid epimerase 2.05302
FGGY FGGY carbohydrate kinase domain containing 2.0529
JOSD1 Josephin domain containing 1 2.05279
ARL4C ADP-ribosylation factor-like 4C 2.05164
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 2.05127
CCDC134 coiled-coil domain containing 134 2.0512
CES2 carboxylesterase 2 2.05117
PIH1D1 PIH1 domain containing 1 2.05091
MTERF4 mitochondrial transcription termination factor 4 2.05076
GPR173 G protein-coupled receptor 173 2.05048
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.04893
HOXB1 homeobox B1 2.04796
PTH1R parathyroid hormone 1 receptor 2.04793
POLH polymerase (DNA directed), eta 2.04754
CYB5R1 cytochrome b5 reductase 1 2.04736
CPNE6 copine VI (neuronal) 2.04623
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.04616
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.04478
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.04379
PCDH7 protocadherin 7 2.04254
ARHGAP1 Rho GTPase activating protein 1 2.04241
OVOL3 ovo-like zinc finger 3 2.03997
ANO3 anoctamin 3 2.03637
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.03594
CA7 carbonic anhydrase VII 2.03591
TRIM46 tripartite motif containing 46 2.03552
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.03379
RAB6B RAB6B, member RAS oncogene family 2.03351
TMEM151B transmembrane protein 151B 2.03343
TNNI2 troponin I type 2 (skeletal, fast) 2.03238
GAS2L1 growth arrest-specific 2 like 1 2.03149
CLDN14 claudin 14 2.03086
ERN1 endoplasmic reticulum to nucleus signaling 1 2.03055
MOBP myelin-associated oligodendrocyte basic protein 2.03017
DPYSL4 dihydropyrimidinase-like 4 2.03014
GHR growth hormone receptor 2.02997
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 2.02993
CRMP1 collapsin response mediator protein 1 2.02875
NTN3 netrin 3 2.02831
VPS35L VPS35 endosomal protein sorting factor like 2.02606
DLX6 distal-less homeobox 6 2.02571
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.02495
NAGA N-acetylgalactosaminidase, alpha- 2.02451
LINC02854 long intergenic non-protein coding RNA 2854 2.02435
DAGLA diacylglycerol lipase, alpha 2.02432
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.02417
FN3K fructosamine 3 kinase 2.02384
SLCO4C1 solute carrier organic anion transporter family, member 4C1 2.02266
CERT1 ceramide transporter 1 2.02254
PARM1 prostate androgen-regulated mucin-like protein 1 2.02162
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.0196
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.01936
BSDC1 BSD domain containing 1 2.01904
PITX3 paired-like homeodomain 3 2.01892
CLEC2D C-type lectin domain family 2, member D 2.01853
PLGLB2 plasminogen-like B2 2.01838
CENPM centromere protein M 2.01766
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 2.0153
GPR68 G protein-coupled receptor 68 2.0146
DNM3 dynamin 3 2.01357
S1PR4 sphingosine-1-phosphate receptor 4 2.01256
STOML1 stomatin (EPB72)-like 1 2.01074
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.00764
ANGPTL2 angiopoietin-like 2 2.00674
LTB4R leukotriene B4 receptor 2.00638
PSKH1 protein serine kinase H1 2.00566
GJA1 gap junction protein, alpha 1, 43kDa 2.00493
GTPBP10 GTP-binding protein 10 (putative) 2.00424
CTSV cathepsin V 2.00371
PRKCD protein kinase C, delta 2.00307
ADAM23 ADAM metallopeptidase domain 23 2.00054
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.00009

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.89512
S100P S100 calcium binding protein P -4.95874
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.60825
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.34588
SLC35F2 solute carrier family 35, member F2 -4.14274
HPRT1 hypoxanthine phosphoribosyltransferase 1 -3.90068
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.61976
JPT1 Jupiter microtubule associated homolog 1 -3.6132
C1QBP complement component 1, q subcomponent binding protein -3.5355
YBX1 Y box binding protein 1 -3.44933
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -3.40038
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.35671
RHOB ras homolog family member B -3.3424
IER3 immediate early response 3 -3.3206
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.26603
RPP38 ribonuclease P/MRP 38kDa subunit -3.2541
UTP11 UTP11 small subunit processome component -3.23926
RHOG ras homolog family member G -3.23838
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -3.21558
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.1914
AKIRIN1 akirin 1 -3.02387
IDE insulin-degrading enzyme -2.98884
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.95826
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -2.94987
SRPRB signal recognition particle receptor, B subunit -2.94146
YAF2 YY1 associated factor 2 -2.93838
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.90974
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.86999
PFN1 profilin 1 -2.84026
FAM222B family with sequence similarity 222, member B -2.83701
BAG2 BCL2-associated athanogene 2 -2.83282
DPP3 dipeptidyl-peptidase 3 -2.82928
HSPA14 heat shock 70kDa protein 14 -2.82303
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.79893
CSK c-src tyrosine kinase -2.79721
ZMPSTE24 zinc metallopeptidase STE24 -2.79592
CD320 CD320 molecule -2.77588
EMC8 ER membrane protein complex subunit 8 -2.77181
GNAS GNAS complex locus -2.77032
MTERF3 mitochondrial transcription termination factor 3 -2.74539
IGFBP4 insulin-like growth factor binding protein 4 -2.73168
PLIN2 perilipin 2 -2.72024
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -2.70348
MARCHF5 membrane associated ring-CH-type finger 5 -2.70276
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.69079
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.67615
MRPS2 mitochondrial ribosomal protein S2 -2.67546
BAZ1A bromodomain adjacent to zinc finger domain, 1A -2.67045
GTF2A2 general transcription factor IIA, 2, 12kDa -2.66058
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.63799
RPP40 ribonuclease P/MRP 40kDa subunit -2.63406
CCNJ cyclin J -2.62248
TSLIG3A tRNA splicing ligase complex subunit 3A -2.61219
TXNDC9 thioredoxin domain containing 9 -2.60982
MED17 mediator complex subunit 17 -2.60892
NOL7 nucleolar protein 7, 27kDa -2.59746
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -2.59342
ENTR1 endosome associated trafficking regulator 1 -2.59299
ANKRD40 ankyrin repeat domain 40 -2.58832
MAK16 MAK16 homolog (S. cerevisiae) -2.58313
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.5818
SCRN1 secernin 1 -2.58146
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.57787
EBNA1BP2 EBNA1 binding protein 2 -2.56874
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.55542
FTL ferritin, light polypeptide -2.55103
DKC1 dyskeratosis congenita 1, dyskerin -2.54796
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -2.54729
GSPT1 G1 to S phase transition 1 -2.54577
LOC112694756 uncharaterized LOC112694756 -2.53805
DERL2 derlin 2 -2.53243
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.50018
CDC20 cell division cycle 20 -2.49607
RBMX2 RNA binding motif protein, X-linked 2 -2.49165
GEMIN2 gem (nuclear organelle) associated protein 2 -2.47764
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.4772
CD151 CD151 molecule (Raph blood group) -2.47482
KIN Kin17 DNA and RNA binding protein -2.46224
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.45903
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.43953
SBNO1 strawberry notch homolog 1 (Drosophila) -2.43633
SELENOF selenoprotein F -2.43058
ECD ecdysoneless homolog (Drosophila) -2.42656
MEMO1 mediator of cell motility 1 -2.41999
ACTG1 actin gamma 1 -2.41535
ZBTB35 zinc finger and BTB domain containing 35 -2.41239
COX5A cytochrome c oxidase subunit Va -2.39777
CHUK conserved helix-loop-helix ubiquitous kinase -2.39587
MRPL12 mitochondrial ribosomal protein L12 -2.38347
RBM38 RNA binding motif protein 38 -2.38323
UCK2 uridine-cytidine kinase 2 -2.37908
CMC2 C-x(9)-C motif containing 2 -2.37875
RFK riboflavin kinase -2.37797
ANKRD17 ankyrin repeat domain 17 -2.3719
CDC123 cell division cycle 123 -2.3605
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.35978
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.35858
DPP8 dipeptidyl-peptidase 8 -2.35823
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -2.35221
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.34725
TMEM185B transmembrane protein 185B -2.34231
RRAGA Ras-related GTP binding A -2.338
GYG1 glycogenin 1 -2.33564
SNIP1 Smad nuclear interacting protein 1 -2.33303
SNRPG small nuclear ribonucleoprotein polypeptide G -2.33252
NUP98 nucleoporin 98kDa -2.32827
CDK8 cyclin-dependent kinase 8 -2.32635
PRMT3 protein arginine methyltransferase 3 -2.32627
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.32479
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.32348
THAP1 THAP domain containing, apoptosis associated protein 1 -2.32133
MRPL42 mitochondrial ribosomal protein L42 -2.31053
PFAS phosphoribosylformylglycinamidine synthase -2.30616
SACS sacsin molecular chaperone -2.29795
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -2.28282
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.28001
CRY1 cryptochrome circadian clock 1 -2.27858
SEC23A Sec23 homolog A (S. cerevisiae) -2.27531
VBP1 von Hippel-Lindau binding protein 1 -2.26938
SEC16A SEC16 homolog A (S. cerevisiae) -2.26844
SMTN smoothelin -2.25994
PDS5A PDS5 cohesin associated factor A -2.24988
DENND4C DENN/MADD domain containing 4C -2.24318
TARS1 threonyl-tRNA synthetase 1 -2.24042
TASOR2 transcription activation suppressor family member 2 -2.23784
ANXA5 annexin A5 -2.23774
TRIT1 tRNA isopentenyltransferase 1 -2.23571
CHMP7 charged multivesicular body protein 7 -2.23227
SSR1 signal sequence receptor, alpha -2.22766
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -2.22726
MRPL3 mitochondrial ribosomal protein L3 -2.2272
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.22395
IPO4 importin 4 -2.22364
KIFBP kinesin family binding protein -2.22343
DAZAP1 DAZ associated protein 1 -2.22159
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.22095
FOXF1 forkhead box F1 -2.21811
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -2.21558
RCOR1 REST corepressor 1 -2.21284
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -2.20996
MTIF2 mitochondrial translational initiation factor 2 -2.20748
COPB1 coatomer protein complex, subunit beta 1 -2.20093
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) -2.19937
RNASE7 ribonuclease, RNase A family, 7 -2.19782
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.19756
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.19383
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.1931
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.19232
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.19058
NELFCD negative elongation factor complex member C/D -2.18478
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.18284
TPM4 tropomyosin 4 -2.17643
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.17626
COX7B cytochrome c oxidase subunit VIIb -2.17372
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.17236
EIF4E eukaryotic translation initiation factor 4E -2.17063
SOCS5 suppressor of cytokine signaling 5 -2.16758
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -2.16009
PRELID3B PRELI domain containing 3B -2.15327
RPL27A ribosomal protein L27a -2.15216
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.14835
ABITRAM actin binding transcription modulator -2.14401
WDR77 WD repeat domain 77 -2.14389
RIOX1 ribosomal oxygenase 1 -2.13813
TPGS1 tubulin polyglutamylase complex subunit 1 -2.13727
TMEM33 transmembrane protein 33 -2.13655
RPN2 ribophorin II -2.13621
BYSL bystin-like -2.13529
SLIRP SRA stem-loop interacting RNA binding protein -2.13525
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -2.13498
DNMBP dynamin binding protein -2.13245
JAM3 junctional adhesion molecule 3 -2.12493
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.12463
MRGBP MRG/MORF4L binding protein -2.12296
DCBLD2 discoidin, CUB and LCCL domain containing 2 -2.12162
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.11995
APOA2 apolipoprotein A-II -2.11767
COMMD3-BMI1 COMMD3-BMI1 readthrough -2.108
ILK integrin-linked kinase -2.10719
PRMT5 protein arginine methyltransferase 5 -2.10676
BANF1 barrier to autointegration factor 1 -2.10451
ZPR1 ZPR1 zinc finger -2.10204
MED28 mediator complex subunit 28 -2.1001
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.09863
PLIN3 perilipin 3 -2.09686
RPL26L1 ribosomal protein L26-like 1 -2.0914
RPS7 ribosomal protein S7 -2.08841
RPS29 ribosomal protein S29 -2.08791
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -2.08625
TIGAR TP53 induced glycolysis regulatory phosphatase -2.08603
ASF1A anti-silencing function 1A histone chaperone -2.08576
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.08248
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -2.08006
NLRP2B NLR family pyrin domain containing 2B -2.07756
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.07659
EXT2 exostosin glycosyltransferase 2 -2.07529
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.07417
AGO2 argonaute RISC catalytic component 2 -2.0708
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.06973
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.06472
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.06452
RPS19 ribosomal protein S19 -2.06335
ATP5F1E ATP synthase F1 subunit epsilon -2.0547
RYK receptor-like tyrosine kinase -2.0545
GABPB1 GA binding protein transcription factor, beta subunit 1 -2.05161
RBM14-RBM4 RBM14-RBM4 readthrough -2.04485
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.04117
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.04058
IL13RA1 interleukin 13 receptor, alpha 1 -2.03729
THOC2 THO complex 2 -2.03558
LRRC59 leucine rich repeat containing 59 -2.03521
ZNF143 zinc finger protein 143 -2.03332
MIS18A MIS18 kinetochore protein A -2.02985
RNF111 ring finger protein 111 -2.02841
NOL8 nucleolar protein 8 -2.02741
DNAAF2 dynein, axonemal, assembly factor 2 -2.02596
RPL9 ribosomal protein L9 -2.02586
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -2.02173
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.02088
RPL38 ribosomal protein L38 -2.02037
JAM2 junctional adhesion molecule 2 -2.01964
KPNA3 karyopherin alpha 3 (importin alpha 4) -2.01959
PSME4 proteasome (prosome, macropain) activator subunit 4 -2.01881
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.01783
APOH apolipoprotein H (beta-2-glycoprotein I) -2.01329
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.01281
HEATR1 HEAT repeat containing 1 -2.01153
MIS12 MIS12 kinetochore complex component -2.01089
E2F6 E2F transcription factor 6 -2.00998
UBE2A ubiquitin-conjugating enzyme E2A -2.00962
MRPL58 mitochondrial ribosomal protein L58 -2.0087
RIOX2 ribosomal oxygenase 2 -2.00857
FASTKD5 FAST kinase domains 5 -2.00695
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.00537
MBD5 methyl-CpG binding domain protein 5 -2.00491
TRIM32 tripartite motif containing 32 -2.00206
BTBD3 BTB (POZ) domain containing 3 -2.00102