CRCGN015_HEPG2_48H:K13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aspirin 99.3 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_HEPG2_48H:K13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EPN2 epsin 2 4.42532
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.95758
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.50729
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.36289

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.45796
EIF5 eukaryotic translation initiation factor 5 -2.87741
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.43572
AURKB aurora kinase B -2.18483
ATG4A autophagy related 4A, cysteine peptidase -2.11168
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.09067
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.02974