CRCGN015_HEPG2_48H:K20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description kynurenic-acid 34.54 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:K20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 5.04855
PHKA1 phosphorylase kinase, alpha 1 (muscle) 4.6959
TXNL4B thioredoxin-like 4B 2.99641
CSK c-src tyrosine kinase 2.67724
MPZL1 myelin protein zero-like 1 2.46355
EAPP E2F-associated phosphoprotein 2.44216
ATOX1 antioxidant 1 copper chaperone 2.31776
TUBA1C tubulin, alpha 1c 2.24134
WIPF2 WAS/WASL interacting protein family, member 2 2.20326
DYNLL1 dynein, light chain, LC8-type 1 2.13805
TUBA1B tubulin, alpha 1b 2.0538
METRN meteorin, glial cell differentiation regulator 2.01747

decreased expression

Symbol Name Standardized Value
SNX7 sorting nexin 7 -4.79701
HEATR1 HEAT repeat containing 1 -4.35557
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -4.05871
TOR1A torsin family 1, member A (torsin A) -2.4877
PLIN2 perilipin 2 -2.33903
BPI bactericidal/permeability-increasing protein -2.32546
ALOX5AP arachidonate 5-lipoxygenase-activating protein -2.30464
CXXC1 CXXC finger protein 1 -2.11179
ZNF239 zinc finger protein 239 -2.09168
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 -2.0755