CRCGN015_HEPG2_48H:K23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tris(2-chloroethyl) phosphate 33.43 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_HEPG2_48H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RFC2 replication factor C (activator 1) 2, 40kDa 6.19231
IL4R interleukin 4 receptor 3.19109
ICAM3 intercellular adhesion molecule 3 2.88215
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.64823
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.31002
RCC1L RCC1 like 2.28048
HPS5 Hermansky-Pudlak syndrome 5 2.1984
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.17625
ABHD11 abhydrolase domain containing 11 2.04364
ZNF638 zinc finger protein 638 2.02713

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.71754
ENOPH1 enolase-phosphatase 1 -3.23518
TM9SF3 transmembrane 9 superfamily member 3 -3.22319
PECR peroxisomal trans-2-enoyl-CoA reductase -3.06358
CYCS cytochrome c, somatic -3.04143
MCUR1 mitochondrial calcium uniporter regulator 1 -3.0109
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.96364
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -2.20321
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.17648
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.10816
DYNLRB1 dynein, light chain, roadblock-type 1 -2.05104
RNF4 ring finger protein 4 -2.04351