| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-phenyl-p-phenylenediamine.hcl 32.93 um perturbation at 48 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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133 genes differentially expressed following the CRCGN015_HEPG2_48H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.96111 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 4.71189 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 3.73875 |
| CRTAP | cartilage associated protein | 3.16114 |
| RNF113A | ring finger protein 113A | 2.96619 |
| C1GALT1C1 | C1GALT1-specific chaperone 1 | 2.89017 |
| GATA2 | GATA binding protein 2 | 2.85654 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.63175 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 2.6162 |
| GOLT1A | golgi transport 1A | 2.58228 |
| GLRX | glutaredoxin (thioltransferase) | 2.52891 |
| HAX1 | HCLS1 associated protein X-1 | 2.52502 |
| EMC7 | ER membrane protein complex subunit 7 | 2.50469 |
| SCAND1 | SCAN domain containing 1 | 2.50274 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.44259 |
| CD8A | CD8a molecule | 2.44083 |
| SAR1B | secretion associated, Ras related GTPase 1B | 2.43922 |
| ABHD4 | abhydrolase domain containing 4 | 2.43215 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.41552 |
| COA3 | cytochrome c oxidase assembly factor 3 | 2.34986 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | 2.34325 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 2.32588 |
| MMP24-AS1-EDEM2 | MMP24-AS1-EDEM2 readthrough | 2.29419 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 2.27766 |
| CRYL1 | crystallin, lambda 1 | 2.2721 |
| UROS | uroporphyrinogen III synthase | 2.26648 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 2.25068 |
| SLC9B2 | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 | 2.25018 |
| CSK | c-src tyrosine kinase | 2.24898 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.24842 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 2.24769 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 2.24706 |
| LAGE3 | L antigen family, member 3 | 2.24624 |
| GABARAP | GABA(A) receptor-associated protein | 2.23818 |
| GSTO1 | glutathione S-transferase omega 1 | 2.22963 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 2.19975 |
| MICB | MHC class I polypeptide-related sequence B | 2.19664 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 2.19148 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 2.18762 |
| GMPR2 | guanosine monophosphate reductase 2 | 2.15219 |
| NCOA4 | nuclear receptor coactivator 4 | 2.14808 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 2.13456 |
| RPS27L | ribosomal protein S27-like | 2.13175 |
| GLB1 | galactosidase, beta 1 | 2.11167 |
| H2BC21 | H2B clustered histone 21 | 2.10589 |
| VAMP8 | vesicle-associated membrane protein 8 | 2.09647 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 2.09158 |
| STAMBP | STAM binding protein | 2.08518 |
| SQOR | sulfide quinone oxidoreductase | 2.08463 |
| IFNG | interferon, gamma | 2.07671 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 2.07396 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 2.06295 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.04501 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 2.0405 |
| PEX11B | peroxisomal biogenesis factor 11 beta | 2.03074 |
| RBKS | ribokinase | 2.03007 |
| COX7B | cytochrome c oxidase subunit VIIb | 2.02592 |
| BLVRA | biliverdin reductase A | 2.02375 |
| RNF167 | ring finger protein 167 | 2.01701 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 | 2.0111 |
| NPC2 | Niemann-Pick disease, type C2 | 2.00988 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 2.00343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -4.80916 |
| EIF5 | eukaryotic translation initiation factor 5 | -4.76448 |
| CXADR | coxsackie virus and adenovirus receptor | -4.72513 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.5197 |
| MT1X | metallothionein 1X | -3.10234 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -3.08388 |
| CENPE | centromere protein E, 312kDa | -3.0171 |
| CA9 | carbonic anhydrase IX | -2.96445 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.66777 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.6534 |
| THOC1 | THO complex 1 | -2.62183 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -2.5619 |
| SLC66A2 | solute carrier family 66 member 2 | -2.48952 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -2.4674 |
| CNTNAP1 | contactin associated protein 1 | -2.43805 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -2.40812 |
| SOX11 | SRY (sex determining region Y)-box 11 | -2.40571 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -2.39445 |
| SOSTDC1 | sclerostin domain containing 1 | -2.37486 |
| PTBP2 | polypyrimidine tract binding protein 2 | -2.35931 |
| ZNF816 | zinc finger protein 816 | -2.34601 |
| ODF1 | outer dense fiber of sperm tails 1 | -2.34049 |
| TUBA3E | tubulin, alpha 3e | -2.33421 |
| MEX3D | mex-3 RNA binding family member D | -2.3296 |
| CSNK1G2 | casein kinase 1, gamma 2 | -2.31745 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -2.31192 |
| ALLC | allantoicase | -2.3092 |
| PKP2 | plakophilin 2 | -2.30793 |
| SYNGR4 | synaptogyrin 4 | -2.30734 |
| LOC102724594 | splicing factor U2AF 35 kDa subunit | -2.29075 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -2.27974 |
| FSCN3 | fascin actin-bundling protein 3, testicular | -2.26784 |
| FJX1 | four jointed box 1 (Drosophila) | -2.25087 |
| GMEB2 | glucocorticoid modulatory element binding protein 2 | -2.19433 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.18071 |
| DAZAP1 | DAZ associated protein 1 | -2.17232 |
| AGAP4 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 | -2.15559 |
| CAPN15 | calpain 15 | -2.14848 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -2.13868 |
| ACTL7A | actin-like 7A | -2.12993 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.12411 |
| SGCE | sarcoglycan, epsilon | -2.12002 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -2.11977 |
| USPL1 | ubiquitin specific peptidase like 1 | -2.11498 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -2.10791 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -2.10489 |
| SAMD4B | sterile alpha motif domain containing 4B | -2.1011 |
| MYL11 | myosin light chain 11 | -2.0987 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 | -2.09764 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.0912 |
| AK8 | adenylate kinase 8 | -2.07291 |
| CDH18 | cadherin 18, type 2 | -2.07107 |
| MTF2 | metal response element binding transcription factor 2 | -2.06778 |
| ACTL7B | actin-like 7B | -2.06491 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | -2.06333 |
| CDK11A | cyclin-dependent kinase 11A | -2.0627 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -2.05993 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.05677 |
| ZNF551 | zinc finger protein 551 | -2.05659 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | -2.05001 |
| MYL9 | myosin, light chain 9, regulatory | -2.04729 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -2.04337 |
| CELF2 | CUGBP, Elav-like family member 2 | -2.04067 |
| BANP | BTG3 associated nuclear protein | -2.04066 |
| CACTIN | cactin, spliceosome C complex subunit | -2.03312 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.03135 |
| DAGLA | diacylglycerol lipase, alpha | -2.02998 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.02475 |
| ACKR2 | atypical chemokine receptor 2 | -2.02471 |
| TEDC2 | tubulin epsilon and delta complex 2 | -2.02393 |
| HBG1 | hemoglobin, gamma A | -2.01473 |
