CRCGN015_HEPG2_48H:L06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-phenyl-p-phenylenediamine.hcl 10.98 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GATA3 GATA binding protein 3 4.29754
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.05483
PPARG peroxisome proliferator-activated receptor gamma 3.54086
MAP2K5 mitogen-activated protein kinase kinase 5 2.70574
NUCB2 nucleobindin 2 2.44732
FCGBP Fc fragment of IgG binding protein 2.29148
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.01811

decreased expression

Symbol Name Standardized Value
PLIN2 perilipin 2 -3.64941
MRPS2 mitochondrial ribosomal protein S2 -3.61602
WASHC4 WASH complex subunit 4 -2.76352
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.65775
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.57948
S100P S100 calcium binding protein P -2.51527
ANAPC2 anaphase promoting complex subunit 2 -2.48912
TBC1D31 TBC1 domain family, member 31 -2.05296