CRCGN015_HEPG2_48H:L07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iq 95.81 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_HEPG2_48H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GATA3 GATA binding protein 3 3.41463
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.19943
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.09033
KIFBP kinesin family binding protein 2.92835
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.89057
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.79123
FPGS folylpolyglutamate synthase 2.74797
KAT6A K(lysine) acetyltransferase 6A 2.43583
ERLIN2 ER lipid raft associated 2 2.17727
CEMIP2 cell migration inducing hyaluronidase 2 2.10974
GOLGA7 golgin A7 2.09364
CRTAP cartilage associated protein 2.06281

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -3.34306
PUF60 poly-U binding splicing factor 60KDa -3.1181
NGRN neugrin, neurite outgrowth associated -2.8946
CD58 CD58 molecule -2.78161
APOH apolipoprotein H (beta-2-glycoprotein I) -2.38075
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -2.28786
ZNF219 zinc finger protein 219 -2.2645
RING1 ring finger protein 1 -2.2517
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.12275
EXOC3 exocyst complex component 3 -2.09702
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.09232
CCDC69 coiled-coil domain containing 69 -2.03251
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.02555
YJU2 YJU2 splicing factor homolog -2.0178
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.01771
CALML5 calmodulin-like 5 -2.01736