CRCGN015_HEPG2_48H:L08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iq 31.94 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN015_HEPG2_48H:L08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 3.63944
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.14631
CXCR4 chemokine (C-X-C motif) receptor 4 2.75062
HDAC4 histone deacetylase 4 2.53888
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2.44554
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.40308
RPP38 ribonuclease P/MRP 38kDa subunit 2.39298
PFKL phosphofructokinase, liver 2.35519
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.21211
KAT6A K(lysine) acetyltransferase 6A 2.19105
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.18182
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.11974
THRAP3 thyroid hormone receptor associated protein 3 2.07158

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -3.83857
PGAM4 phosphoglycerate mutase family member 4 -3.82413
ANXA5 annexin A5 -3.63771
S100P S100 calcium binding protein P -3.03337
LYPLA1 lysophospholipase I -2.89632
COG7 component of oligomeric golgi complex 7 -2.56665
HEATR1 HEAT repeat containing 1 -2.42074
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.36793
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -2.29939
BPHL biphenyl hydrolase-like (serine hydrolase) -2.25424
ETNK2 ethanolamine kinase 2 -2.16655
ERO1B endoplasmic reticulum oxidoreductase 1 beta -2.14569
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.11791
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -2.0814
HAX1 HCLS1 associated protein X-1 -2.0683
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.0394
MACROH2A2 macroH2A.2 histone -2.00126