CRCGN015_HEPG2_48H:L10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 97.3 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_HEPG2_48H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 5.50217
UBE2A ubiquitin-conjugating enzyme E2A 2.36475
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.30331
SCFD1 sec1 family domain containing 1 2.26394
BRCA1 breast cancer 1, early onset 2.14558
NPTN neuroplastin 2.13712
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough 2.12498
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.07508
ZIC1 Zic family member 1 2.05577
EAPP E2F-associated phosphoprotein 2.02498

decreased expression

Symbol Name Standardized Value
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.20033
MT1X metallothionein 1X -3.11554
CXADR coxsackie virus and adenovirus receptor -3.11302
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.3249
CD58 CD58 molecule -2.24483
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.2135
COG2 component of oligomeric golgi complex 2 -2.13213
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.10192
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.08631