CRCGN015_HEPG2_48H:L15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description etodolac 11.09 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_HEPG2_48H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.06748
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.47572
EPHB2 EPH receptor B2 3.46271
GSTZ1 glutathione S-transferase zeta 1 3.42404
MINDY1 MINDY lysine 48 deubiquitinase 1 3.27608
PRR7 proline rich 7 (synaptic) 3.18919
ANO10 anoctamin 10 3.06439
ADAT1 adenosine deaminase, tRNA-specific 1 2.90138
DENND2D DENN/MADD domain containing 2D 2.80308
PLSCR3 phospholipid scramblase 3 2.66977
UBE2A ubiquitin-conjugating enzyme E2A 2.66176
PCNT pericentrin 2.65172
PFKL phosphofructokinase, liver 2.60594
SATB1 SATB homeobox 1 2.52117
ZNF222 zinc finger protein 222 2.36192
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.17897
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2.14635
RAB15 RAB15, member RAS oncogene family 2.14038

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -6.1549
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -6.14348
TM9SF3 transmembrane 9 superfamily member 3 -5.09594
CDC20 cell division cycle 20 -3.68079
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.75333
PECR peroxisomal trans-2-enoyl-CoA reductase -2.67558
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.26758
IL12RB2 interleukin 12 receptor, beta 2 -2.25323
RAI14 retinoic acid induced 14 -2.24369
ATG4A autophagy related 4A, cysteine peptidase -2.17843
SPAG7 sperm associated antigen 7 -2.1053