CRCGN015_HEPG2_48H:L17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,3-dibromo-1-propanol 33.6 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EXOSC4 exosome component 4 4.96491
CXCL2 chemokine (C-X-C motif) ligand 2 3.93267
BAD BCL2-associated agonist of cell death 2.98012
SNX11 sorting nexin 11 2.54826
IGHMBP2 immunoglobulin mu binding protein 2 2.50771
UTRN utrophin 2.05915

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.40126
PLIN2 perilipin 2 -3.16295
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.86947
TSPAN4 tetraspanin 4 -2.62702
MRPS2 mitochondrial ribosomal protein S2 -2.17675
DEFA6 defensin, alpha 6, Paneth cell-specific -2.08413