CRCGN015_HEPG2_48H:L23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 32.77 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_HEPG2_48H:L23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.01034
ZFP36 ZFP36 ring finger protein 3.62626
CXCR4 chemokine (C-X-C motif) receptor 4 3.61424
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.50397
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.87278
FZD7 frizzled class receptor 7 2.67786
TIMP2 TIMP metallopeptidase inhibitor 2 2.64275
JADE2 jade family PHD finger 2 2.57715
CDC25A cell division cycle 25A 2.02136

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -3.94041
CCNB1 cyclin B1 -3.15468
FBXL12 F-box and leucine-rich repeat protein 12 -3.10673
PDZD2 PDZ domain containing 2 -2.80038
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.66239
PDLIM1 PDZ and LIM domain 1 -2.61762
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.42209
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.37419
HEBP1 heme binding protein 1 -2.20621
MCUR1 mitochondrial calcium uniporter regulator 1 -2.16296
RNF10 ring finger protein 10 -2.06919
TM9SF3 transmembrane 9 superfamily member 3 -2.03168
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.0271
GTF2IRD1 GTF2I repeat domain containing 1 -2.02598