CRCGN015_HEPG2_48H:M06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethyl hydrogen phosphite 11.14 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_HEPG2_48H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 4.63089
ABHD4 abhydrolase domain containing 4 4.3893
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.94718
TRIB1 tribbles pseudokinase 1 2.49555
COPS7A COP9 signalosome subunit 7A 2.38364
DAD1 defender against cell death 1 2.3496
SYNE2 spectrin repeat containing, nuclear envelope 2 2.31581
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.31471
DEFA6 defensin, alpha 6, Paneth cell-specific 2.1523

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.87024
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -3.58514
AURKB aurora kinase B -2.93921
UFM1 ubiquitin-fold modifier 1 -2.92059
S100P S100 calcium binding protein P -2.84745
PLIN2 perilipin 2 -2.74567
TRIB3 tribbles pseudokinase 3 -2.66853
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.32147
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -2.0316
SYCP2 synaptonemal complex protein 2 -2.0167