CRCGN015_HEPG2_48H:M12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methylhydrazine sulfate 11.2 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPOX protoporphyrinogen oxidase 3.77301
MAST2 microtubule associated serine/threonine kinase 2 3.59792
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.04041
KLHL21 kelch-like family member 21 3.00457
CZIB CXXC motif containing zinc binding protein 2.17456
RHOBTB1 Rho-related BTB domain containing 1 2.16843

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -4.35218
BIRC2 baculoviral IAP repeat containing 2 -4.0901
EIF5 eukaryotic translation initiation factor 5 -4.08515
TM9SF3 transmembrane 9 superfamily member 3 -2.92369
CXADR coxsackie virus and adenovirus receptor -2.15215
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.12418
SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1 -2.02593
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.01843