CRCGN015_HEPG2_48H:M13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichloroethane 96.8 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_HEPG2_48H:M13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 4.60017
KDM5A lysine (K)-specific demethylase 5A 3.83527
FPGS folylpolyglutamate synthase 2.82063
UBE2A ubiquitin-conjugating enzyme E2A 2.74685

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.27992
MT1X metallothionein 1X -3.08692
PECR peroxisomal trans-2-enoyl-CoA reductase -2.67745
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.47343
CDC20 cell division cycle 20 -2.3675
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.07301
LIAS lipoic acid synthetase -2.03193