| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,2-dichloroethane 10.76 um perturbation at 48 h in HEPG2 (Carcinogenome) |
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60 genes differentially expressed following the CRCGN015_HEPG2_48H:M15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.42746 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 3.24333 |
| COQ8A | coenzyme Q8A | 2.61287 |
| SAR1B | secretion associated, Ras related GTPase 1B | 2.52508 |
| NUTF2 | nuclear transport factor 2 | 2.50874 |
| COMMD3 | COMM domain containing 3 | 2.39315 |
| MED18 | mediator complex subunit 18 | 2.37129 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 2.3516 |
| SSUH2 | ssu-2 homolog (C. elegans) | 2.33917 |
| ZNF124 | zinc finger protein 124 | 2.32471 |
| SELPLG | selectin P ligand | 2.29722 |
| MRPL58 | mitochondrial ribosomal protein L58 | 2.25996 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 2.22317 |
| RBBP5 | retinoblastoma binding protein 5 | 2.21717 |
| C1GALT1C1 | C1GALT1-specific chaperone 1 | 2.19973 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.18411 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 2.17786 |
| MTA2 | metastasis associated 1 family, member 2 | 2.1723 |
| RANBP6 | RAN binding protein 6 | 2.15995 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2.12821 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | 2.12047 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 2.118 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 2.11297 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 2.08357 |
| NEK3 | NIMA-related kinase 3 | 2.07762 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 2.07706 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 2.0756 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 2.0542 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 | 2.03909 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | 2.03391 |
| STRN3 | striatin, calmodulin binding protein 3 | 2.02409 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.02028 |
| CCL16 | chemokine (C-C motif) ligand 16 | 2.00775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -4.91023 |
| MT1X | metallothionein 1X | -4.82003 |
| HEATR1 | HEAT repeat containing 1 | -4.60386 |
| S100P | S100 calcium binding protein P | -4.52444 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -4.27859 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -3.73478 |
| LDHD | lactate dehydrogenase D | -3.58044 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -3.33448 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -3.19112 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.95423 |
| VAT1 | vesicle amine transport 1 | -2.931 |
| CHGB | chromogranin B | -2.56225 |
| CSRP2 | cysteine and glycine-rich protein 2 | -2.55437 |
| TP53BP2 | tumor protein p53 binding protein 2 | -2.48066 |
| LINC02762 | long intergenic non-protein coding RNA 2762 | -2.44522 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.43586 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -2.34309 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -2.21634 |
| CAPN15 | calpain 15 | -2.21304 |
| SAMD4B | sterile alpha motif domain containing 4B | -2.15651 |
| IL7R | interleukin 7 receptor | -2.11581 |
| SLIT2 | slit homolog 2 (Drosophila) | -2.07506 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -2.07243 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -2.0599 |
| CBX7 | chromobox homolog 7 | -2.04786 |
| FGF9 | fibroblast growth factor 9 | -2.0207 |
| RNF187 | ring finger protein 187 | -2.00261 |