CRCGN015_HEPG2_48H:M19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mestranol 97.87 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN015_HEPG2_48H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 4.44013
BAD BCL2-associated agonist of cell death 4.31079
EVL Enah/Vasp-like 2.92953
EAPP E2F-associated phosphoprotein 2.57472
LOC114841035 uncharacterized LOC114841035 2.42439
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.3969
FSD1 fibronectin type III and SPRY domain containing 1 2.39585
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.24742
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 2.23442
EEF1B2 eukaryotic translation elongation factor 1 beta 2 2.07174
MCUB mitochondrial calcium uniporter dominant negative subunit beta 2.05826
KATNA1 katanin p60 (ATPase containing) subunit A 1 2.05076
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.04081
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.00856

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.93263
CETN3 centrin, EF-hand protein, 3 -4.1028
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.83561
FBXL12 F-box and leucine-rich repeat protein 12 -3.60865
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.45631
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.97696
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.44036
TP53BP1 tumor protein p53 binding protein 1 -2.16956
RAB11A RAB11A, member RAS oncogene family -2.1077