CRCGN015_HEPG2_48H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mestranol 32.62 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN015_HEPG2_48H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WDR7 WD repeat domain 7 4.29227
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.10458
IPO13 importin 13 3.5918
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.95619
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.75258
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.46259
KIFBP kinesin family binding protein 2.28132
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.25412
USP9Y ubiquitin specific peptidase 9, Y-linked 2.03247

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -4.74645
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.13622
ADGRE5 adhesion G protein-coupled receptor E5 -2.01088