CRCGN015_HEPG2_48H:M21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mestranol 10.87 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_HEPG2_48H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 5.03613
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.95707
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.86214
CRELD2 cysteine-rich with EGF-like domains 2 2.34773
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2.27807
GALP galanin-like peptide 2.21627
INSL4 insulin-like 4 (placenta) 2.15113
SYNC syncoilin, intermediate filament protein 2.09019
LRRC31 leucine rich repeat containing 31 2.06599
ESRP1 epithelial splicing regulatory protein 1 2.00782
TNNC1 troponin C type 1 (slow) 2.00591

decreased expression

Symbol Name Standardized Value
HEBP1 heme binding protein 1 -4.61652
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.12412
CDC20 cell division cycle 20 -3.95385
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.75871
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.38936
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.8328
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.69334
SYNGR3 synaptogyrin 3 -2.32739
TM9SF3 transmembrane 9 superfamily member 3 -2.22622
ACADVL acyl-CoA dehydrogenase, very long chain -2.15316
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) -2.12469
STX1A syntaxin 1A (brain) -2.09702
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -2.02677
ANXA5 annexin A5 -2.02315