CRCGN015_HEPG2_48H:M22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitropyrene 101.93 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

1002 genes differentially expressed following the CRCGN015_HEPG2_48H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 7.83552
ABHD4 abhydrolase domain containing 4 7.45888
INPP1 inositol polyphosphate-1-phosphatase 7.38527
RALGDS ral guanine nucleotide dissociation stimulator 7.35915
BLCAP bladder cancer associated protein 6.73125
MICALL1 MICAL-like 1 6.32562
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 6.13761
LRP10 low density lipoprotein receptor-related protein 10 6.11967
TIGAR TP53 induced glycolysis regulatory phosphatase 5.98689
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 5.66762
PHLDA3 pleckstrin homology-like domain, family A, member 3 5.5823
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.55272
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.39529
SESN1 sestrin 1 4.60544
TUBB6 tubulin, beta 6 class V 4.50464
DDB2 damage-specific DNA binding protein 2, 48kDa 4.48542
GPC1 glypican 1 4.43798
ZNF79 zinc finger protein 79 4.36259
FDXR ferredoxin reductase 4.34822
LOXL1 lysyl oxidase-like 1 4.31583
MAPK13 mitogen-activated protein kinase 13 4.29269
GALNS galactosamine (N-acetyl)-6-sulfatase 4.1851
BTG2 BTG family, member 2 4.15565
TBC1D2 TBC1 domain family, member 2 4.14856
THSD1 thrombospondin, type I, domain containing 1 4.14818
CDIP1 cell death-inducing p53 target 1 4.124
FOSL1 FOS-like antigen 1 4.04481
CCDC92 coiled-coil domain containing 92 4.00086
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.96531
LOC122526780 uncharacterized LOC122526780 3.93422
ZMAT3 zinc finger, matrin-type 3 3.89734
SCPEP1 serine carboxypeptidase 1 3.88899
GLTP glycolipid transfer protein 3.79451
NSUN3 NOP2/Sun domain family, member 3 3.76523
HOXA1 homeobox A1 3.74875
DUSP14 dual specificity phosphatase 14 3.7474
MAPKBP1 mitogen-activated protein kinase binding protein 1 3.74466
IL4R interleukin 4 receptor 3.73816
XPC xeroderma pigmentosum, complementation group C 3.73489
FASN fatty acid synthase 3.73377
ADGRG1 adhesion G protein-coupled receptor G1 3.72509
CXCL13 chemokine (C-X-C motif) ligand 13 3.70904
ZNF211 zinc finger protein 211 3.64074
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.63729
EPHA2 EPH receptor A2 3.62481
TXLNA taxilin alpha 3.61527
ADRB2 adrenoceptor beta 2, surface 3.573
CEL carboxyl ester lipase 3.56688
MKNK2 MAP kinase interacting serine/threonine kinase 2 3.52699
GSDME gasdermin E 3.5096
FAM131A family with sequence similarity 131, member A 3.50297
PPME1 protein phosphatase methylesterase 1 3.46755
STAT1 signal transducer and activator of transcription 1, 91kDa 3.45901
GABARAPL1 GABA(A) receptor-associated protein like 1 3.43704
CSRNP2 cysteine-serine-rich nuclear protein 2 3.42777
UFM1 ubiquitin-fold modifier 1 3.41987
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.41496
CCDC90B coiled-coil domain containing 90B 3.39344
CBR3 carbonyl reductase 3 3.39075
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.35104
EDN2 endothelin 2 3.33823
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 3.32379
TRAFD1 TRAF-type zinc finger domain containing 1 3.32337
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 3.30392
BASP1 brain abundant, membrane attached signal protein 1 3.30303
HEBP1 heme binding protein 1 3.28357
HOXA10 homeobox A10 3.27158
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 3.26879
MICALL2 MICAL-like 2 3.26328
TMEM59 transmembrane protein 59 3.25442
SDC4 syndecan 4 3.247
HSPB1 heat shock 27kDa protein 1 3.23983
MMP9 matrix metallopeptidase 9 3.23563
TOR1B torsin family 1, member B (torsin B) 3.22975
EPS8L2 EPS8-like 2 3.22226
TERF2IP telomeric repeat binding factor 2, interacting protein 3.20305
RNF25 ring finger protein 25 3.19886
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 3.19038
SURF2 surfeit 2 3.18835
COL7A1 collagen, type VII, alpha 1 3.14393
TBK1 TANK-binding kinase 1 3.14381
STARD5 StAR-related lipid transfer (START) domain containing 5 3.14094
MAP7D1 MAP7 domain containing 1 3.13332
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.10244
ERCC3 excision repair cross-complementation group 3 3.09451
SIRT7 sirtuin 7 3.08791
STEAP3 STEAP family member 3, metalloreductase 3.0826
CALCOCO1 calcium binding and coiled-coil domain 1 3.06808
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 3.06592
CHIC2 cysteine-rich hydrophobic domain 2 3.0622
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.05394
TWF2 twinfilin actin binding protein 2 3.04448
PLK3 polo-like kinase 3 3.0438
TRIAP1 TP53 regulated inhibitor of apoptosis 1 3.03412
ZNF23 zinc finger protein 23 3.01508
TMEM40 transmembrane protein 40 2.99462
H2AB2 H2A.B variant histone 2 2.99025
GRN granulin 2.98828
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.98756
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.98724
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.98427
CLCA2 chloride channel accessory 2 2.98215
PRKCD protein kinase C, delta 2.93913
TOB1 transducer of ERBB2, 1 2.93869
KDSR 3-ketodihydrosphingosine reductase 2.93154
GBP2 guanylate binding protein 2, interferon-inducible 2.9286
KHNYN KH and NYN domain containing 2.92775
ANXA8L1 annexin A8-like 1 2.90443
LAMB3 laminin, beta 3 2.89458
MAN1B1 mannosidase, alpha, class 1B, member 1 2.89429
GSAP gamma-secretase activating protein 2.89386
HSPA4L heat shock 70kDa protein 4-like 2.88309
CXCL9 chemokine (C-X-C motif) ligand 9 2.88308
EGR1 early growth response 1 2.86317
SLAMF8 SLAM family member 8 2.85177
GPR87 G protein-coupled receptor 87 2.85102
CBX6 chromobox homolog 6 2.84246
PAOX polyamine oxidase (exo-N4-amino) 2.84011
DOK7 docking protein 7 2.8247
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.81893
KRT17 keratin 17, type I 2.81507
PARP12 poly (ADP-ribose) polymerase family, member 12 2.81225
KRI1 KRI1 homolog (S. cerevisiae) 2.80491
EHBP1L1 EH domain binding protein 1-like 1 2.80061
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.79947
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.79736
ZNF692 zinc finger protein 692 2.79388
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.79338
REXO2 RNA exonuclease 2 2.78514
AMPD2 adenosine monophosphate deaminase 2 2.78455
PAGE4 P antigen family, member 4 (prostate associated) 2.77648
STOM stomatin 2.77495
ULK1 unc-51 like autophagy activating kinase 1 2.76698
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.75591
ZNF557 zinc finger protein 557 2.75558
RIC8A RIC8 guanine nucleotide exchange factor A 2.74889
SP140L SP140 nuclear body protein-like 2.74644
NMRK1 nicotinamide riboside kinase 1 2.74471
TOR1A torsin family 1, member A (torsin A) 2.74334
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.73732
DNASE1L1 deoxyribonuclease I-like 1 2.73381
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.73016
CROT carnitine O-octanoyltransferase 2.7275
PLTP phospholipid transfer protein 2.72737
SLC75A1 solute carrier family 75 member 1 2.72329
USP33 ubiquitin specific peptidase 33 2.71944
PERP PERP, TP53 apoptosis effector 2.71416
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.70702
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.69659
TSPYL2 TSPY-like 2 2.69469
CD82 CD82 molecule 2.6901
DGKA diacylglycerol kinase, alpha 80kDa 2.68909
S100A11 S100 calcium binding protein A11 2.67661
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.67083
TKTL1 transketolase-like 1 2.67036
PHF1 PHD finger protein 1 2.66346
ULBP2 UL16 binding protein 2 2.66273
TUT7 terminal uridylyl transferase 7 2.66212
GTF2B general transcription factor IIB 2.66155
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.65915
RNPEP arginyl aminopeptidase (aminopeptidase B) 2.65417
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.65337
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.64983
INPPL1 inositol polyphosphate phosphatase-like 1 2.64449
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.63663
IER3 immediate early response 3 2.63295
LITAF lipopolysaccharide-induced TNF factor 2.62488
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.62141
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.61763
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.6099
GCC1 GRIP and coiled-coil domain containing 1 2.60675
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 2.60322
SLC49A3 solute carrier family 49 member 3 2.59829
PDLIM7 PDZ and LIM domain 7 (enigma) 2.59768
CD9 CD9 molecule 2.59483
FICD FIC domain containing 2.59064
DERL2 derlin 2 2.5896
COL17A1 collagen, type XVII, alpha 1 2.58739
ITGAV integrin, alpha V 2.58625
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.58571
KDM7A lysine (K)-specific demethylase 7A 2.57779
SLFN12 schlafen family member 12 2.57694
SLC48A1 solute carrier family 48 (heme transporter), member 1 2.57477
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.57085
IPO13 importin 13 2.56782
FAM234B family with sequence similarity 234 member B 2.5668
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.56677
IGF2R insulin-like growth factor 2 receptor 2.56328
PLSCR3 phospholipid scramblase 3 2.56286
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.55945
CCDC86 coiled-coil domain containing 86 2.55916
POMZP3 POM121 and ZP3 fusion 2.55009
ASB6 ankyrin repeat and SOCS box containing 6 2.54947
ZBTB43 zinc finger and BTB domain containing 43 2.5463
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.54509
PTK7 protein tyrosine kinase 7 (inactive) 2.54502
FAM50B family with sequence similarity 50, member B 2.53505
SFTPA2 surfactant protein A2 2.53034
COL4A5 collagen, type IV, alpha 5 2.52761
TDP2 tyrosyl-DNA phosphodiesterase 2 2.52483
MBD1 methyl-CpG binding domain protein 1 2.51053
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.50678
ZC3H12A zinc finger CCCH-type containing 12A 2.50447
JMJD7 jumonji domain containing 7 2.49434
CD52 CD52 molecule 2.49305
SAA2 serum amyloid A2 2.49139
TRIP6 thyroid hormone receptor interactor 6 2.48938
USB1 U6 snRNA biogenesis 1 2.48901
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.48886
SIGLEC15 sialic acid binding Ig-like lectin 15 2.4858
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.48317
JAG2 jagged 2 2.48117
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.47844
PER3 period circadian clock 3 2.46858
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.46254
ATG4A autophagy related 4A, cysteine peptidase 2.4624
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.45475
ITPKC inositol-trisphosphate 3-kinase C 2.44972
HECA headcase homolog (Drosophila) 2.44538
ZSCAN16 zinc finger and SCAN domain containing 16 2.44197
BTN2A1 butyrophilin, subfamily 2, member A1 2.44013
NRIP3 nuclear receptor interacting protein 3 2.43447
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.4313
CCP110 centriolar coiled coil protein 110kDa 2.42799
GSTM3 glutathione S-transferase mu 3 (brain) 2.41829
FBN2 fibrillin 2 2.4173
TRIM22 tripartite motif containing 22 2.41529
SUN2 Sad1 and UNC84 domain containing 2 2.41482
TSEN34 TSEN34 tRNA splicing endonuclease subunit 2.41154
NADSYN1 NAD synthetase 1 2.40801
FAT2 FAT atypical cadherin 2 2.40661
CARD8 caspase recruitment domain family, member 8 2.40546
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.40461
LIN37 lin-37 DREAM MuvB core complex component 2.39971
IER2 immediate early response 2 2.39867
HLA-C major histocompatibility complex, class I, C 2.39803
NME3 NME/NM23 nucleoside diphosphate kinase 3 2.39782
SGSH N-sulfoglucosamine sulfohydrolase 2.39069
PTGES prostaglandin E synthase 2.38849
TOR4A torsin family 4, member A 2.38204
KAT2B K(lysine) acetyltransferase 2B 2.38148
YBX3 Y box binding protein 3 2.37788
EIF4A2 eukaryotic translation initiation factor 4A2 2.37654
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.37547
UBTD1 ubiquitin domain containing 1 2.36995
H2AC6 H2A clustered histone 6 2.36648
TRIM39-RPP21 TRIM39-RPP21 readthrough 2.36472
RALB v-ral simian leukemia viral oncogene homolog B 2.36067
DRAM1 DNA-damage regulated autophagy modulator 1 2.35732
SKIC2 SKI2 subunit of superkiller complex 2.35686
FBXO3 F-box protein 3 2.35356
BEX4 brain expressed, X-linked 4 2.34645
RND3 Rho family GTPase 3 2.34638
CERS4 ceramide synthase 4 2.34214
TSPO translocator protein (18kDa) 2.34201
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 2.34118
SFXN3 sideroflexin 3 2.34109
ADPGK ADP-dependent glucokinase 2.33964
BMP1 bone morphogenetic protein 1 2.33665
GPR153 G protein-coupled receptor 153 2.33645
ANGPTL2 angiopoietin-like 2 2.33421
CEMIP2 cell migration inducing hyaluronidase 2 2.33376
ELMO2 engulfment and cell motility 2 2.33054
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.32929
LOC114841035 uncharacterized LOC114841035 2.32894
MED9 mediator complex subunit 9 2.32851
ZNF140 zinc finger protein 140 2.32664
ZFTRAF1 zinc finger TRAF-type containing 1 2.3265
CIRSR corepressor of RBPJ and splicing regulator 2.32397
RIOK3 RIO kinase 3 2.30865
IP6K2 inositol hexakisphosphate kinase 2 2.3078
OXSR1 oxidative stress responsive 1 2.30281
APMAP adipocyte plasma membrane associated protein 2.30163
BAX BCL2-associated X protein 2.30045
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.30043
CBX7 chromobox homolog 7 2.2991
SYNGR3 synaptogyrin 3 2.29905
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.29802
KEAP1 kelch-like ECH-associated protein 1 2.29788
TRIM62 tripartite motif containing 62 2.29742
HHAT hedgehog acyltransferase 2.29067
TUBG2 tubulin, gamma 2 2.28803
AIRIM AFG2 interacting ribosome maturation factor 2.28117
RAB38 RAB38, member RAS oncogene family 2.27878
AVPI1 arginine vasopressin-induced 1 2.27799
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.27346
GYS1 glycogen synthase 1 (muscle) 2.27082
CSAD cysteine sulfinic acid decarboxylase 2.26994
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.26299
ZNF276 zinc finger protein 276 2.26184
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.26029
BGLAP bone gamma-carboxyglutamate (gla) protein 2.25847
TMEM134 transmembrane protein 134 2.25589
KRT5 keratin 5, type II 2.25531
ARHGAP22 Rho GTPase activating protein 22 2.25425
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.25261
AMZ2 archaelysin family metallopeptidase 2 2.25184
CLDN4 claudin 4 2.25141
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.25114
CDC37L1 cell division cycle 37-like 1 2.24254
TSC1 tuberous sclerosis 1 2.24248
DTD1 D-tyrosyl-tRNA deacylase 1 2.23932
AAGAB alpha- and gamma-adaptin binding protein 2.23741
CHMP1B charged multivesicular body protein 1B 2.23615
TNNI2 troponin I type 2 (skeletal, fast) 2.23598
TDG thymine-DNA glycosylase 2.23495
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.23195
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.23057
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 2.22859
BCL10 B-cell CLL/lymphoma 10 2.22362
CLEC16A C-type lectin domain family 16, member A 2.22038
NOTCH1 notch 1 2.21867
ZNF226 zinc finger protein 226 2.21756
CA8 carbonic anhydrase VIII 2.21702
KIZ kizuna centrosomal protein 2.21534
FBXL12 F-box and leucine-rich repeat protein 12 2.21413
KDM5C lysine (K)-specific demethylase 5C 2.21313
TUFT1 tuftelin 1 2.21251
PLD3 phospholipase D family, member 3 2.21103
EMC7 ER membrane protein complex subunit 7 2.21078
TP53I3 tumor protein p53 inducible protein 3 2.20933
TMEM9B TMEM9 domain family, member B 2.20724
CYBC1 cytochrome b-245 chaperone 1 2.20588
CHIT1 chitinase 1 (chitotriosidase) 2.20427
FRS2 fibroblast growth factor receptor substrate 2 2.2025
GADD45A growth arrest and DNA-damage-inducible, alpha 2.19804
FPGS folylpolyglutamate synthase 2.19452
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.19361
MAPK12 mitogen-activated protein kinase 12 2.19353
CHMP5 charged multivesicular body protein 5 2.19155
CHPF2 chondroitin polymerizing factor 2 2.19127
SOWAHC sosondowah ankyrin repeat domain family member C 2.19111
CDK9 cyclin-dependent kinase 9 2.19082
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.18699
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.18427
HLA-B major histocompatibility complex, class I, B 2.18423
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.18395
DUSP6 dual specificity phosphatase 6 2.18381
PLEC plectin 2.1837
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.18343
ZNF324 zinc finger protein 324 2.18312
EHF ets homologous factor 2.18244
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.18203
H2BC21 H2B clustered histone 21 2.18096
ECM1 extracellular matrix protein 1 2.17987
HCFC2 host cell factor C2 2.17686
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.17512
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.17454
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.17232
ZNF562 zinc finger protein 562 2.16928
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.16738
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 2.16093
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.16086
CXCL11 chemokine (C-X-C motif) ligand 11 2.15913
PINK1 PTEN induced putative kinase 1 2.15712
SPEG SPEG complex locus 2.15679
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 2.15659
EMC6 ER membrane protein complex subunit 6 2.15495
ACBD3 acyl-CoA binding domain containing 3 2.15456
ACADVL acyl-CoA dehydrogenase, very long chain 2.15178
ATOSB atos homolog B 2.14924
NUP58 nucleoporin 58 2.14728
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.14691
ISCU iron-sulfur cluster assembly enzyme 2.13518
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.13368
ZNF45 zinc finger protein 45 2.13323
NTAN1 N-terminal asparagine amidase 2.13322
AKIP1 A kinase (PRKA) interacting protein 1 2.12906
GM2A GM2 ganglioside activator 2.12901
BRD2 bromodomain containing 2 2.12775
RAB5IF RAB5 interacting factor 2.12746
MTRF1 mitochondrial translational release factor 1 2.12194
SMAD3 SMAD family member 3 2.12081
GCC2 GRIP and coiled-coil domain containing 2 2.12059
MORC3 MORC family CW-type zinc finger 3 2.11838
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough 2.11554
UBE2H ubiquitin-conjugating enzyme E2H 2.11269
ACP2 acid phosphatase 2, lysosomal 2.10917
BECN1 beclin 1, autophagy related 2.10327
YPEL5 yippee-like 5 (Drosophila) 2.09835
THBS3 thrombospondin 3 2.09532
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.09427
UPK3B uroplakin 3B 2.09285
CCNL2 cyclin L2 2.09193
C1QL1 complement component 1, q subcomponent-like 1 2.09155
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.09075
EML2 echinoderm microtubule associated protein like 2 2.08878
TRNAU1AP tRNA selenocysteine 1 associated protein 1 2.08733
LIMK2 LIM domain kinase 2 2.08557
GAA glucosidase, alpha; acid 2.08384
NINL ninein-like 2.08197
FKBPL FK506 binding protein like 2.07894
AEN apoptosis enhancing nuclease 2.07867
RIN2 Ras and Rab interactor 2 2.07809
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.07808
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.07746
CCL5 chemokine (C-C motif) ligand 5 2.07681
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.07261
CAPN10 calpain 10 2.07251
ISL1 ISL LIM homeobox 1 2.06433
NINJ1 ninjurin 1 2.06341
CTSL cathepsin L 2.06026
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 2.05549
ACTA2 actin, alpha 2, smooth muscle, aorta 2.05534
LRRC47 leucine rich repeat containing 47 2.05363
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.0528
HABP4 hyaluronan binding protein 4 2.05259
ALCAM activated leukocyte cell adhesion molecule 2.05149
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.05109
ELL3 elongation factor RNA polymerase II-like 3 2.04959
COQ6 coenzyme Q6 monooxygenase 2.04912
IQSEC2 IQ motif and Sec7 domain 2 2.04859
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.04381
HOOK3 hook microtubule-tethering protein 3 2.04163
IRF1 interferon regulatory factor 1 2.04137
MACROH2A1 macroH2A.1 histone 2.03988
FAM50A family with sequence similarity 50, member A 2.0382
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.0377
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.03718
CLBA1 clathrin binding box of aftiphilin containing 1 2.03502
GATA2 GATA binding protein 2 2.03491
CYB5R1 cytochrome b5 reductase 1 2.03348
PRDM4 PR domain containing 4 2.03273
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.0327
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.03189
RNF208 ring finger protein 208 2.03094
FXR2 fragile X mental retardation, autosomal homolog 2 2.03015
IFNG interferon, gamma 2.03002
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.0291
GLRX2 glutaredoxin 2 2.02867
CORO2A coronin, actin binding protein, 2A 2.02818
ATF3 activating transcription factor 3 2.02793
TRIM38 tripartite motif containing 38 2.02782
CYTH4 cytohesin 4 2.02726
ZNF281 zinc finger protein 281 2.02722
PMP22 peripheral myelin protein 22 2.02553
OFD1 oral-facial-digital syndrome 1 2.02501
BCAS4 breast carcinoma amplified sequence 4 2.02403
PHF2 PHD finger protein 2 2.02187
PORCN porcupine homolog (Drosophila) 2.02145
ZBTB17 zinc finger and BTB domain containing 17 2.02075
MMP12 matrix metallopeptidase 12 2.01686
BCL2L2 BCL2-like 2 2.01542
KCTD9 potassium channel tetramerization domain containing 9 2.01469
NKX2-5 NK2 homeobox 5 2.01404
PLCH2 phospholipase C, eta 2 2.014
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.01057
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.0094
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.00831

decreased expression

Symbol Name Standardized Value
PLIN2 perilipin 2 -8.34284
APOH apolipoprotein H (beta-2-glycoprotein I) -7.65803
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -7.17076
APOA2 apolipoprotein A-II -7.0198
IL17RB interleukin 17 receptor B -6.81441
MCM3 minichromosome maintenance complex component 3 -5.92443
NFIL3 nuclear factor, interleukin 3 regulated -5.66006
PROM1 prominin 1 -5.21881
PYCR1 pyrroline-5-carboxylate reductase 1 -4.98598
RPS4Y1 ribosomal protein S4, Y-linked 1 -4.35172
MPC2 mitochondrial pyruvate carrier 2 -4.28533
HADH hydroxyacyl-CoA dehydrogenase -4.27322
ELOVL6 ELOVL fatty acid elongase 6 -4.20428
RNASE4 ribonuclease, RNase A family, 4 -4.19016
FYN FYN proto-oncogene, Src family tyrosine kinase -4.07147
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -4.00469
MCM6 minichromosome maintenance complex component 6 -3.85921
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.81549
XYLT1 xylosyltransferase I -3.80204
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -3.76414
MCM5 minichromosome maintenance complex component 5 -3.72675
ARL2 ADP-ribosylation factor-like 2 -3.70999
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.70094
HMGA2 high mobility group AT-hook 2 -3.69581
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.66064
FLT3 fms-related tyrosine kinase 3 -3.63237
AURKB aurora kinase B -3.62304
RSU1 Ras suppressor protein 1 -3.60043
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.59407
PLK1 polo-like kinase 1 -3.58527
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -3.58126
DMAC2L distal membrane arm assembly component 2 like -3.56048
RNF130 ring finger protein 130 -3.55448
CCDC170 coiled-coil domain containing 170 -3.54964
TF transferrin -3.5358
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.53137
FAM117A family with sequence similarity 117, member A -3.51977
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.51874
CCNA2 cyclin A2 -3.51292
RBM3 RNA binding motif (RNP1, RRM) protein 3 -3.50935
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -3.47913
MTREX Mtr4 exosome RNA helicase -3.45351
GIPC2 GIPC PDZ domain containing family, member 2 -3.45291
CZIB CXXC motif containing zinc binding protein -3.40674
KIF15 kinesin family member 15 -3.40241
TSPAN7 tetraspanin 7 -3.39212
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.36934
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.35398
SEC31A SEC31 homolog A (S. cerevisiae) -3.33844
STMN1 stathmin 1 -3.33367
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -3.32827
FBF1 Fas (TNFRSF6) binding factor 1 -3.32108
MCM10 minichromosome maintenance complex component 10 -3.29994
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -3.2862
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -3.27516
PUF60 poly-U binding splicing factor 60KDa -3.26647
ADRA2C adrenoceptor alpha 2C -3.26399
GAS2 growth arrest-specific 2 -3.26176
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -3.25966
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.24076
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.24013
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.23823
DCK deoxycytidine kinase -3.23646
MYLK myosin light chain kinase -3.23294
PHACTR2 phosphatase and actin regulator 2 -3.22498
FZD4 frizzled class receptor 4 -3.19022
PFAS phosphoribosylformylglycinamidine synthase -3.18406
RGS7 regulator of G-protein signaling 7 -3.17952
DPYSL2 dihydropyrimidinase-like 2 -3.16272
DAZAP1 DAZ associated protein 1 -3.16096
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.16024
TASP1 taspase, threonine aspartase, 1 -3.15971
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.09439
RBMX RNA binding motif protein, X-linked -3.08787
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -3.08708
PHKB phosphorylase kinase, beta -3.08421
PECR peroxisomal trans-2-enoyl-CoA reductase -3.08323
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -3.07344
AHSG alpha-2-HS-glycoprotein -3.06699
TTC27 tetratricopeptide repeat domain 27 -3.06441
KIF4A kinesin family member 4A -3.05487
C4BPA complement component 4 binding protein, alpha -3.05197
APOM apolipoprotein M -3.04237
SPC25 SPC25, NDC80 kinetochore complex component -3.0396
SEPHS1 selenophosphate synthetase 1 -3.03772
TCF12 transcription factor 12 -3.02603
FBXO5 F-box protein 5 -3.02372
A1CF APOBEC1 complementation factor -3.02266
SNRPA small nuclear ribonucleoprotein polypeptide A -3.01816
PLK4 polo-like kinase 4 -3.01461
ZNF587B zinc finger protein 587B -3.00858
NPR2 natriuretic peptide receptor 2 -2.97239
STIL SCL/TAL1 interrupting locus -2.96896
ATF6 activating transcription factor 6 -2.96732
CDK4 cyclin-dependent kinase 4 -2.95742
CDK7 cyclin-dependent kinase 7 -2.95707
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.95686
CDC45 cell division cycle 45 -2.94833
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.94464
RGN regucalcin -2.94309
PPARG peroxisome proliferator-activated receptor gamma -2.9364
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.93582
NCK2 NCK adaptor protein 2 -2.93095
SIAH1 siah E3 ubiquitin protein ligase 1 -2.92813
BRCA1 breast cancer 1, early onset -2.92131
MSH2 mutS homolog 2 -2.91303
KIF18B kinesin family member 18B -2.91045
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.9079
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.90672
RHOBTB1 Rho-related BTB domain containing 1 -2.89765
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.89077
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -2.88426
HACL2 2-hydroxyacyl-CoA lyase 2 -2.84529
CD320 CD320 molecule -2.84217
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.84066
PSRC1 proline/serine-rich coiled-coil 1 -2.83376
BIRC5 baculoviral IAP repeat containing 5 -2.83152
ANG angiogenin, ribonuclease, RNase A family, 5 -2.82766
RABL3 RAB, member of RAS oncogene family-like 3 -2.81924
WDR18 WD repeat domain 18 -2.81354
AP3B1 adaptor-related protein complex 3, beta 1 subunit -2.79415
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.78811
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.7851
RNF144A ring finger protein 144A -2.78006
TTK TTK protein kinase -2.77985
ADNP2 ADNP homeobox 2 -2.77209
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.76569
NASP nuclear autoantigenic sperm protein (histone-binding) -2.76477
GPER1 G protein-coupled estrogen receptor 1 -2.75536
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.75534
LRRC40 leucine rich repeat containing 40 -2.75461
CDT1 chromatin licensing and DNA replication factor 1 -2.75282
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.75164
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.7429
INTS9 integrator complex subunit 9 -2.74087
FABP7 fatty acid binding protein 7, brain -2.74017
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.73843
ANAPC1 anaphase promoting complex subunit 1 -2.73766
NUP93 nucleoporin 93kDa -2.73719
DHFR dihydrofolate reductase -2.7332
TRIM24 tripartite motif containing 24 -2.72258
NLRP4 NLR family, pyrin domain containing 4 -2.72089
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.72001
EPS15 epidermal growth factor receptor pathway substrate 15 -2.71702
TBC1D5 TBC1 domain family, member 5 -2.71652
GPHN gephyrin -2.71533
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.70899
FBLN5 fibulin 5 -2.70419
ERI3 ERI1 exoribonuclease family member 3 -2.69388
VRK1 vaccinia related kinase 1 -2.69007
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.68055
CLOCK clock circadian regulator -2.67549
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.67125
SKA1 spindle and kinetochore associated complex subunit 1 -2.6699
ANAPC15 anaphase promoting complex subunit 15 -2.6682
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.66728
PTBP1 polypyrimidine tract binding protein 1 -2.66623
MCM7 minichromosome maintenance complex component 7 -2.66522
EDNRB endothelin receptor type B -2.66211
DERA deoxyribose-phosphate aldolase (putative) -2.65812
LRRC59 leucine rich repeat containing 59 -2.65514
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -2.65299
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.64744
KAT5 K(lysine) acetyltransferase 5 -2.64295
CD7 CD7 molecule -2.63946
USP1 ubiquitin specific peptidase 1 -2.63616
KIF14 kinesin family member 14 -2.63312
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -2.63257
ELP4 elongator acetyltransferase complex subunit 4 -2.62951
ASB13 ankyrin repeat and SOCS box containing 13 -2.62925
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.62811
IFT52 intraflagellar transport 52 -2.62535
CDC20 cell division cycle 20 -2.62211
CETN3 centrin, EF-hand protein, 3 -2.61854
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.6166
SMYD3 SET and MYND domain containing 3 -2.61636
QPRT quinolinate phosphoribosyltransferase -2.61067
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.60397
DUT deoxyuridine triphosphatase -2.60299
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.60179
WBP11 WW domain binding protein 11 -2.6008
ARHGAP11A Rho GTPase activating protein 11A -2.59885
SF3A2 splicing factor 3a, subunit 2, 66kDa -2.598
RUVBL2 RuvB-like AAA ATPase 2 -2.59148
PXMP2 peroxisomal membrane protein 2, 22kDa -2.58655
KIF11 kinesin family member 11 -2.586
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -2.58315
UGP2 UDP-glucose pyrophosphorylase 2 -2.57543
TTC28 tetratricopeptide repeat domain 28 -2.57505
UBA2 ubiquitin-like modifier activating enzyme 2 -2.57433
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.57088
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.56703
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.56399
MIS18BP1 MIS18 binding protein 1 -2.56122
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.55911
ANKRD28 ankyrin repeat domain 28 -2.55323
MRPL3 mitochondrial ribosomal protein L3 -2.5498
FAM171A1 family with sequence similarity 171, member A1 -2.54829
PGM1 phosphoglucomutase 1 -2.54617
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.5432
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.54128
NANOG Nanog homeobox -2.54017
PGLS 6-phosphogluconolactonase -2.53693
UBAP2 ubiquitin associated protein 2 -2.53675
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.53519
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.53099
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.53054
ANO10 anoctamin 10 -2.52968
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.52856
GPN1 GPN-loop GTPase 1 -2.5282
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.52681
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.5255
AMBP alpha-1-microglobulin/bikunin precursor -2.52466
EML4 echinoderm microtubule associated protein like 4 -2.52118
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.51743
GLDC glycine dehydrogenase (decarboxylating) -2.51456
NBAS neuroblastoma amplified sequence -2.50988
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.50597
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.50595
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.50445
ADRA2A adrenoceptor alpha 2A -2.50411
PCBP1 poly(rC) binding protein 1 -2.50277
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.49572
THOC7 THO complex 7 -2.49288
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.4897
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.4887
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.48717
DOCK2 dedicator of cytokinesis 2 -2.48546
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.48391
LBR lamin B receptor -2.48242
AXIN1 axin 1 -2.48076
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.48054
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.4805
DET1 de-etiolated homolog 1 (Arabidopsis) -2.4793
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.47692
LAMA2 laminin, alpha 2 -2.47406
TRMT5 tRNA methyltransferase 5 -2.47399
H2AZ1 H2A.Z variant histone 1 -2.47378
CALB1 calbindin 1, 28kDa -2.47168
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.47164
MKI67 marker of proliferation Ki-67 -2.46718
NECTIN3 nectin cell adhesion molecule 3 -2.45911
LIME1 Lck interacting transmembrane adaptor 1 -2.45882
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.45792
ANK2 ankyrin 2, neuronal -2.45577
MYO5C myosin VC -2.45408
TRH thyrotropin-releasing hormone -2.45359
CBX5 chromobox homolog 5 -2.44786
PDZK1 PDZ domain containing 1 -2.44647
SRSF2 serine/arginine-rich splicing factor 2 -2.44004
GLRX5 glutaredoxin 5 -2.43561
PTPRK protein tyrosine phosphatase, receptor type, K -2.43555
SINHCAF SIN3-HDAC complex associated factor -2.43409
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.43219
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.43044
TRMT61B tRNA methyltransferase 61B -2.42996
SCGN secretagogin, EF-hand calcium binding protein -2.42981
NCAPH non-SMC condensin I complex, subunit H -2.42895
H2AZ2 H2A.Z variant histone 2 -2.4273
USP39 ubiquitin specific peptidase 39 -2.42709
UBAP2L ubiquitin associated protein 2-like -2.4265
COPZ1 coatomer protein complex, subunit zeta 1 -2.41774
PHYH phytanoyl-CoA 2-hydroxylase -2.41615
MGLL monoglyceride lipase -2.41522
VASH2 vasohibin 2 -2.41405
MCM4 minichromosome maintenance complex component 4 -2.41367
CD36 CD36 molecule (thrombospondin receptor) -2.41021
MAOB monoamine oxidase B -2.40587
CADPS2 Ca++-dependent secretion activator 2 -2.40518
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -2.40419
MCMBP minichromosome maintenance complex binding protein -2.40264
VSNL1 visinin-like 1 -2.39934
AVEN apoptosis, caspase activation inhibitor -2.39765
CTCF CCCTC-binding factor (zinc finger protein) -2.39751
NREP neuronal regeneration related protein -2.39428
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.39366
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.39207
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.38295
TYRO3 TYRO3 protein tyrosine kinase -2.38256
GJB1 gap junction protein, beta 1, 32kDa -2.38187
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.38184
CCNB2 cyclin B2 -2.38059
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.37957
GMPS guanine monphosphate synthase -2.37899
AKAP12 A kinase (PRKA) anchor protein 12 -2.3741
ITGB5 integrin, beta 5 -2.36881
KCTD11 potassium channel tetramerization domain containing 11 -2.3675
AGMAT agmatine ureohydrolase (agmatinase) -2.36719
PRMT7 protein arginine methyltransferase 7 -2.36524
SELENBP1 selenium binding protein 1 -2.36099
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.359
EHBP1 EH domain binding protein 1 -2.35639
ZNF286A zinc finger protein 286A -2.35262
HSPB2 heat shock 27kDa protein 2 -2.35242
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.35056
MBNL3 muscleblind-like splicing regulator 3 -2.34985
LIMS2 LIM and senescent cell antigen-like domains 2 -2.3493
ASXL2 additional sex combs like transcriptional regulator 2 -2.34822
COL5A3 collagen, type V, alpha 3 -2.34706
DCAF6 DDB1 and CUL4 associated factor 6 -2.34639
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.34352
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -2.34309
CPB2 carboxypeptidase B2 (plasma) -2.33939
TMEM97 transmembrane protein 97 -2.33903
ILK integrin-linked kinase -2.3367
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.33537
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -2.33398
CDCA3 cell division cycle associated 3 -2.33389
SALL1 spalt-like transcription factor 1 -2.33297
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.33137
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.33106
IL23A interleukin 23, alpha subunit p19 -2.32987
PROS1 protein S (alpha) -2.3296
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.32937
ASL argininosuccinate lyase -2.32905
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -2.32014
ZMYM4 zinc finger, MYM-type 4 -2.31915
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.31841
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.31828
SLC30A10 solute carrier family 30, member 10 -2.31561
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.315
TBXAS1 thromboxane A synthase 1 (platelet) -2.31478
CER1 cerberus 1, DAN family BMP antagonist -2.31363
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -2.31286
CTPS2 CTP synthase 2 -2.3121
SAE1 SUMO1 activating enzyme subunit 1 -2.30675
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.30388
PRDX4 peroxiredoxin 4 -2.30297
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.30197
ACSS3 acyl-CoA synthetase short-chain family member 3 -2.30196
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.29951
LRRC17 leucine rich repeat containing 17 -2.29868
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.29821
GALK2 galactokinase 2 -2.29766
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.2966
FGL1 fibrinogen-like 1 -2.29549
DPPA4 developmental pluripotency associated 4 -2.29539
NUP54 nucleoporin 54kDa -2.29486
TM4SF5 transmembrane 4 L six family member 5 -2.29479
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.29379
NCOA3 nuclear receptor coactivator 3 -2.28916
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.28385
SNX5 sorting nexin 5 -2.28271
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -2.28214
ASGR1 asialoglycoprotein receptor 1 -2.28029
KHK ketohexokinase (fructokinase) -2.27978
CPZ carboxypeptidase Z -2.27903
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -2.27854
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.27734
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -2.27675
WRN Werner syndrome, RecQ helicase-like -2.27457
PRC1 protein regulator of cytokinesis 1 -2.27415
ASRGL1 asparaginase like 1 -2.27212
CENPB centromere protein B, 80kDa -2.26552
FOXN2 forkhead box N2 -2.25714
FGFR4 fibroblast growth factor receptor 4 -2.25692
GFUS GDP-L-fucose synthase -2.25643
SPAG5 sperm associated antigen 5 -2.2551
IGFBP1 insulin-like growth factor binding protein 1 -2.2546
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.25115
GSTCD glutathione S-transferase, C-terminal domain containing -2.24993
SRSF3 serine/arginine-rich splicing factor 3 -2.24874
EMID1 EMI domain containing 1 -2.2487
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.24653
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.24541
NCALD neurocalcin delta -2.24321
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.2418
FBL fibrillarin -2.24125
SRBD1 S1 RNA binding domain 1 -2.23807
CD2AP CD2-associated protein -2.23493
CLIC4 chloride intracellular channel 4 -2.23492
CAMKMT calmodulin-lysine N-methyltransferase -2.23425
GPC3 glypican 3 -2.23421
ATAD5 ATPase family, AAA domain containing 5 -2.23374
FGA fibrinogen alpha chain -2.23317
PGM3 phosphoglucomutase 3 -2.23112
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.23076
AGXT alanine-glyoxylate aminotransferase -2.2292
AACS acetoacetyl-CoA synthetase -2.22893
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.22824
BMP6 bone morphogenetic protein 6 -2.22625
KAT8 K(lysine) acetyltransferase 8 -2.22586
BCLAF1 BCL2-associated transcription factor 1 -2.22281
EIF3K eukaryotic translation initiation factor 3, subunit K -2.21813
ZFP69B ZFP69 zinc finger protein B -2.21706
DNAAF2 dynein, axonemal, assembly factor 2 -2.21683
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.21485
PEAK1 pseudopodium-enriched atypical kinase 1 -2.21237
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.21104
ZHX2 zinc fingers and homeoboxes 2 -2.2092
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.19997
PPA2 pyrophosphatase (inorganic) 2 -2.19935
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -2.19878
CHL1 cell adhesion molecule L1-like -2.19451
PAH phenylalanine hydroxylase -2.19348
MSH6 mutS homolog 6 -2.19344
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.19274
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.19144
MFAP5 microfibrillar associated protein 5 -2.19123
FOCAD focadhesin -2.19044
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.18852
PLPP1 phospholipid phosphatase 1 -2.18676
EXOSC9 exosome component 9 -2.18631
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -2.18408
HAVCR1 hepatitis A virus cellular receptor 1 -2.18035
BABAM2 BRISC and BRCA1 A complex member 2 -2.17963
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -2.17928
HEATR1 HEAT repeat containing 1 -2.17911
FGB fibrinogen beta chain -2.17902
LAMP5 lysosomal-associated membrane protein family, member 5 -2.17723
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -2.1766
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.17635
CHEK1 checkpoint kinase 1 -2.17586
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -2.17542
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.17453
NPTX1 neuronal pentraxin I -2.17414
CD207 CD207 molecule, langerin -2.17384
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.17283
BHMT2 betaine--homocysteine S-methyltransferase 2 -2.16907
SELE selectin E -2.1687
CA9 carbonic anhydrase IX -2.16691
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.16618
RMDN1 regulator of microtubule dynamics 1 -2.15985
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.15883
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.15587
GRB10 growth factor receptor-bound protein 10 -2.15561
CFI complement factor I -2.15466
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -2.15402
HCFC1 host cell factor C1 -2.14869
CPNE2 copine II -2.14636
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.14392
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.14202
CFAP20 cilia and flagella associated protein 20 -2.14158
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.13904
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.1362
TRAPPC9 trafficking protein particle complex 9 -2.13516
PRSS2 protease, serine, 2 (trypsin 2) -2.13062
HNRNPR heterogeneous nuclear ribonucleoprotein R -2.12942
CGREF1 cell growth regulator with EF-hand domain 1 -2.12939
HMGB2 high mobility group box 2 -2.12911
CD99 CD99 molecule -2.12891
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.12843
SF3B5 splicing factor 3b, subunit 5, 10kDa -2.12553
BEX2 brain expressed X-linked 2 -2.12417
KRT1 keratin 1, type II -2.12237
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.12162
FXYD2 FXYD domain containing ion transport regulator 2 -2.11877
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.1176
MTMR2 myotubularin related protein 2 -2.11726
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.11698
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.11575
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.1154
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.11413
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.11364
ORC3 origin recognition complex, subunit 3 -2.11294
MAP4 microtubule-associated protein 4 -2.10906
SOAT2 sterol O-acyltransferase 2 -2.10849
MRPS27 mitochondrial ribosomal protein S27 -2.1063
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.10562
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.10379
ETFB electron-transfer-flavoprotein, beta polypeptide -2.09735
CYREN cell cycle regulator of NHEJ -2.09528
DENND10 DENN domain containing 10 -2.09374
MIS18A MIS18 kinetochore protein A -2.09365
DPP4 dipeptidyl-peptidase 4 -2.09356
METTL9 methyltransferase like 9 -2.09104
PDE8A phosphodiesterase 8A -2.09044
GSTM5 glutathione S-transferase mu 5 -2.0902
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.08609
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.08125
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.08085
FXYD7 FXYD domain containing ion transport regulator 7 -2.08045
COL9A3 collagen, type IX, alpha 3 -2.07806
PNPLA3 patatin-like phospholipase domain containing 3 -2.0774
TFF1 trefoil factor 1 -2.07729
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -2.0772
KIF2C kinesin family member 2C -2.07525
PMP2 peripheral myelin protein 2 -2.07485
HBG1 hemoglobin, gamma A -2.07365
APOA1 apolipoprotein A-I -2.07104
ADH6 alcohol dehydrogenase 6 (class V) -2.07093
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.06891
CSE1L CSE1 chromosome segregation 1-like (yeast) -2.06847
MRPL23 mitochondrial ribosomal protein L23 -2.06703
ZIC3 Zic family member 3 -2.06628
LRPPRC leucine-rich pentatricopeptide repeat containing -2.0611
ZSCAN5A zinc finger and SCAN domain containing 5A -2.06043
RAB8B RAB8B, member RAS oncogene family -2.05946
SERINC5 serine incorporator 5 -2.05898
RBP1 retinol binding protein 1, cellular -2.05822
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.05778
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.05768
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.05528
SHCBP1 SHC SH2-domain binding protein 1 -2.05512
CCDC7 coiled-coil domain containing 7 -2.05344
CDC25B cell division cycle 25B -2.0526
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -2.05238
PRIM1 primase, DNA, polypeptide 1 (49kDa) -2.04839
STAP2 signal transducing adaptor family member 2 -2.04629
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.04627
HAS2 hyaluronan synthase 2 -2.0425
VIL1 villin 1 -2.04233
MPC1 mitochondrial pyruvate carrier 1 -2.04077
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -2.04077
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.04052
OSBPL9 oxysterol binding protein-like 9 -2.04045
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.03957
VCAM1 vascular cell adhesion molecule 1 -2.03921
HSPA12A heat shock 70kDa protein 12A -2.03919
STIM1 stromal interaction molecule 1 -2.03726
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -2.03506
PCBP2 poly(rC) binding protein 2 -2.03491
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.03431
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.03361
BBOF1 basal body orientation factor 1 -2.03093
SQLE squalene epoxidase -2.03069
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.03067
YJU2 YJU2 splicing factor homolog -2.02989
GALP galanin-like peptide -2.02954
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.02942
NUP205 nucleoporin 205kDa -2.02814
SRFBP1 serum response factor binding protein 1 -2.02715
MDN1 MDN1, midasin homolog (yeast) -2.02672
CP ceruloplasmin (ferroxidase) -2.02579
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -2.0241
NUBPL nucleotide binding protein-like -2.0225
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.02212
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -2.02178
TPK1 thiamin pyrophosphokinase 1 -2.02155
FAM184A family with sequence similarity 184, member A -2.02118
KIF1B kinesin family member 1B -2.02079
PCP4 Purkinje cell protein 4 -2.02063
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -2.01934
PMM2 phosphomannomutase 2 -2.01881
GLYAT glycine-N-acyltransferase -2.01869
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.01869
TCP1 t-complex 1 -2.01756
SRP72 signal recognition particle 72kDa -2.01677
PDF peptide deformylase (mitochondrial) -2.01643
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.01555
FABP1 fatty acid binding protein 1, liver -2.01537
FGG fibrinogen gamma chain -2.01466
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -2.01325
LARS1 leucyl-tRNA synthetase 1 -2.01285
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.01039
ZNF280B zinc finger protein 280B -2.008
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing -2.00785
CLDN10 claudin 10 -2.00748
CYB5A cytochrome b5 type A (microsomal) -2.00663
SELENOF selenoprotein F -2.00379
TRAT1 T cell receptor associated transmembrane adaptor 1 -2.00365
RBM14-RBM4 RBM14-RBM4 readthrough -2.00234
QARS1 glutaminyl-tRNA synthetase 1 -2.00097