CRCGN015_HEPG2_48H:M23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitropyrene 33.98 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

1038 genes differentially expressed following the CRCGN015_HEPG2_48H:M23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 9.48014
CDPF1 cysteine-rich, DPF motif domain containing 1 8.43336
RALGDS ral guanine nucleotide dissociation stimulator 7.4178
INPP1 inositol polyphosphate-1-phosphatase 7.38182
MICALL1 MICAL-like 1 7.08526
BLCAP bladder cancer associated protein 6.96972
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 6.55759
LRP10 low density lipoprotein receptor-related protein 10 6.45201
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.12946
SKIC2 SKI2 subunit of superkiller complex 5.98663
PHLDA3 pleckstrin homology-like domain, family A, member 3 5.84844
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.71165
FDXR ferredoxin reductase 5.49809
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 5.36588
DDB2 damage-specific DNA binding protein 2, 48kDa 5.33936
TIGAR TP53 induced glycolysis regulatory phosphatase 5.31855
THSD1 thrombospondin, type I, domain containing 1 5.29389
MAPK13 mitogen-activated protein kinase 13 4.8903
SESN1 sestrin 1 4.86978
BTG2 BTG family, member 2 4.55089
IL4R interleukin 4 receptor 4.49354
ZMAT3 zinc finger, matrin-type 3 4.46532
ZNF79 zinc finger protein 79 4.42539
CXCL13 chemokine (C-X-C motif) ligand 13 4.34631
TXLNA taxilin alpha 4.12486
NSUN3 NOP2/Sun domain family, member 3 4.07631
DHRS7 dehydrogenase/reductase (SDR family) member 7 4.07182
UFM1 ubiquitin-fold modifier 1 4.00827
EPS8L2 EPS8-like 2 4.00451
DUSP14 dual specificity phosphatase 14 4.00444
LOXL1 lysyl oxidase-like 1 3.98544
SCPEP1 serine carboxypeptidase 1 3.96932
CDIP1 cell death-inducing p53 target 1 3.9612
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 3.9272
ADRB2 adrenoceptor beta 2, surface 3.92252
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.90876
RABGGTA Rab geranylgeranyltransferase, alpha subunit 3.88188
GALNS galactosamine (N-acetyl)-6-sulfatase 3.84818
GPC1 glypican 1 3.83134
TERF2IP telomeric repeat binding factor 2, interacting protein 3.81406
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.79502
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.774
EPHA2 EPH receptor A2 3.77117
LOC122526780 uncharacterized LOC122526780 3.76873
FOSL1 FOS-like antigen 1 3.76297
CEL carboxyl ester lipase 3.73941
TOB1 transducer of ERBB2, 1 3.72438
IER3 immediate early response 3 3.71593
FASN fatty acid synthase 3.62523
PAOX polyamine oxidase (exo-N4-amino) 3.62295
TWF2 twinfilin actin binding protein 2 3.57462
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 3.56382
HSPB1 heat shock 27kDa protein 1 3.52129
GLTP glycolipid transfer protein 3.51577
TDP2 tyrosyl-DNA phosphodiesterase 2 3.50186
SDC4 syndecan 4 3.49386
EGR1 early growth response 1 3.48048
CCDC90B coiled-coil domain containing 90B 3.44385
MICALL2 MICAL-like 2 3.40516
ZNF212 zinc finger protein 212 3.37735
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 3.37577
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.3736
H2AC6 H2A clustered histone 6 3.33842
STARD5 StAR-related lipid transfer (START) domain containing 5 3.33195
GABARAPL1 GABA(A) receptor-associated protein like 1 3.31955
INPPL1 inositol polyphosphate phosphatase-like 1 3.30815
SCRIB scribbled planar cell polarity protein 3.29682
FAM131A family with sequence similarity 131, member A 3.29446
REXO2 RNA exonuclease 2 3.28978
SIRT7 sirtuin 7 3.28406
GSDME gasdermin E 3.2753
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 3.26235
TRAFD1 TRAF-type zinc finger domain containing 1 3.2595
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 3.24902
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 3.24843
BAX BCL2-associated X protein 3.24
GRN granulin 3.23373
HEBP1 heme binding protein 1 3.22911
TBK1 TANK-binding kinase 1 3.20666
SOWAHC sosondowah ankyrin repeat domain family member C 3.19024
CCDC86 coiled-coil domain containing 86 3.17016
CERS4 ceramide synthase 4 3.16457
MKNK2 MAP kinase interacting serine/threonine kinase 2 3.16309
MAPKBP1 mitogen-activated protein kinase binding protein 1 3.16151
CSRNP2 cysteine-serine-rich nuclear protein 2 3.1509
CYBC1 cytochrome b-245 chaperone 1 3.14292
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 3.1429
CHD8 chromodomain helicase DNA binding protein 8 3.13997
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 3.13986
RRAGC Ras-related GTP binding C 3.1282
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 3.12051
PRKCD protein kinase C, delta 3.11805
RHOF ras homolog family member F (in filopodia) 3.11462
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 3.09318
ZNF211 zinc finger protein 211 3.09249
COL17A1 collagen, type XVII, alpha 1 3.08764
PAGE4 P antigen family, member 4 (prostate associated) 3.08746
SGSH N-sulfoglucosamine sulfohydrolase 3.08738
PERP PERP, TP53 apoptosis effector 3.07744
MAN1B1 mannosidase, alpha, class 1B, member 1 3.07198
SFTPA2 surfactant protein A2 3.0382
XYLT2 xylosyltransferase II 3.02996
CBX6 chromobox homolog 6 3.02802
KHNYN KH and NYN domain containing 3.02426
KRT17 keratin 17, type I 3.01687
AOAH acyloxyacyl hydrolase (neutrophil) 3.01511
TRIAP1 TP53 regulated inhibitor of apoptosis 1 3.01454
IER2 immediate early response 2 3.01088
STOM stomatin 3.01067
STAT1 signal transducer and activator of transcription 1, 91kDa 3.00894
RNF25 ring finger protein 25 3.00718
KIFC3 kinesin family member C3 2.99933
CCND3 cyclin D3 2.99701
ERCC3 excision repair cross-complementation group 3 2.9773
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.97279
RNPEP arginyl aminopeptidase (aminopeptidase B) 2.95894
RAB38 RAB38, member RAS oncogene family 2.95795
TMEM59 transmembrane protein 59 2.95315
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.93921
COL4A5 collagen, type IV, alpha 5 2.93504
JAG2 jagged 2 2.93109
GCC1 GRIP and coiled-coil domain containing 1 2.92238
FAM50B family with sequence similarity 50, member B 2.91058
ZNF23 zinc finger protein 23 2.90582
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.90059
CALCOCO1 calcium binding and coiled-coil domain 1 2.90016
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.89492
TRIM38 tripartite motif containing 38 2.89386
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.88589
USB1 U6 snRNA biogenesis 1 2.8857
EDN2 endothelin 2 2.87196
GPR87 G protein-coupled receptor 87 2.87128
TJAP1 tight junction associated protein 1 (peripheral) 2.85604
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.85332
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.85178
SPATA20 spermatogenesis associated 20 2.82061
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.81551
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.81302
PTGES prostaglandin E synthase 2.81291
SLC49A3 solute carrier family 49 member 3 2.81187
H2BC21 H2B clustered histone 21 2.80392
CD52 CD52 molecule 2.80128
YIPF3 Yip1 domain family, member 3 2.79867
EHBP1L1 EH domain binding protein 1-like 1 2.79555
MAP7D1 MAP7 domain containing 1 2.78013
LAMB3 laminin, beta 3 2.78012
TUT7 terminal uridylyl transferase 7 2.77947
CLCA2 chloride channel accessory 2 2.77821
XPC xeroderma pigmentosum, complementation group C 2.77247
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.77216
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.75942
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.7418
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.74008
SURF2 surfeit 2 2.72941
CTSL cathepsin L 2.72634
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.72132
GCLC glutamate-cysteine ligase, catalytic subunit 2.71686
RIOK3 RIO kinase 3 2.71592
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 2.70995
ZNF589 zinc finger protein 589 2.70947
ELMO2 engulfment and cell motility 2 2.70107
AVPI1 arginine vasopressin-induced 1 2.70097
AMPD2 adenosine monophosphate deaminase 2 2.69711
GTF2B general transcription factor IIB 2.69342
PLXNB2 plexin B2 2.69115
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.68967
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.68728
CCDC92 coiled-coil domain containing 92 2.68328
ZNF226 zinc finger protein 226 2.68059
PLEC plectin 2.67898
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.67573
CHIC2 cysteine-rich hydrophobic domain 2 2.66566
H2AB2 H2A.B variant histone 2 2.65609
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.6515
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.65109
DTD1 D-tyrosyl-tRNA deacylase 1 2.64893
CHMP5 charged multivesicular body protein 5 2.6478
BCL6 B-cell CLL/lymphoma 6 2.64349
TBC1D2 TBC1 domain family, member 2 2.63769
HSPA4L heat shock 70kDa protein 4-like 2.63343
RNF39 ring finger protein 39 2.63325
MXI1 MAX interactor 1, dimerization protein 2.63058
C1QL1 complement component 1, q subcomponent-like 1 2.62459
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.62372
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.62078
GSAP gamma-secretase activating protein 2.61663
OFD1 oral-facial-digital syndrome 1 2.61551
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.61418
SLC48A1 solute carrier family 48 (heme transporter), member 1 2.61366
CCDC51 coiled-coil domain containing 51 2.60847
IP6K2 inositol hexakisphosphate kinase 2 2.60688
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.60266
GPR153 G protein-coupled receptor 153 2.59999
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.59935
TOR1A torsin family 1, member A (torsin A) 2.59929
CLBA1 clathrin binding box of aftiphilin containing 1 2.58792
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.5874
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.58595
IL21R interleukin 21 receptor 2.58531
HOXA1 homeobox A1 2.58319
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.57988
MED9 mediator complex subunit 9 2.5756
RND3 Rho family GTPase 3 2.5661
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.55023
STEAP3 STEAP family member 3, metalloreductase 2.54238
ANXA8L1 annexin A8-like 1 2.53556
LAP3 leucine aminopeptidase 3 2.53447
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.53421
AEN apoptosis enhancing nuclease 2.53406
ITPKC inositol-trisphosphate 3-kinase C 2.52959
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.52855
CHPF2 chondroitin polymerizing factor 2 2.52508
CYTH4 cytohesin 4 2.52486
RETREG2 reticulophagy regulator family member 2 2.52281
ATF3 activating transcription factor 3 2.52279
LITAF lipopolysaccharide-induced TNF factor 2.5203
DUSP5 dual specificity phosphatase 5 2.51983
RIPK4 receptor-interacting serine-threonine kinase 4 2.51532
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.51449
TMEM40 transmembrane protein 40 2.51334
BECN1 beclin 1, autophagy related 2.51122
ZNF692 zinc finger protein 692 2.50994
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.50898
DSG3 desmoglein 3 2.50758
KEAP1 kelch-like ECH-associated protein 1 2.50686
MDFI MyoD family inhibitor 2.50514
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 2.50479
TOR4A torsin family 4, member A 2.49607
UBAP1 ubiquitin associated protein 1 2.49455
PROSER1 proline and serine rich 1 2.48737
GDE1 glycerophosphodiester phosphodiesterase 1 2.48382
SEC31B SEC31 homolog B (S. cerevisiae) 2.48136
ARSA arylsulfatase A 2.48072
BATF basic leucine zipper transcription factor, ATF-like 2.47629
TOR1B torsin family 1, member B (torsin B) 2.47538
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.47298
PPME1 protein phosphatase methylesterase 1 2.4694
PLK3 polo-like kinase 3 2.4682
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.46748
COL7A1 collagen, type VII, alpha 1 2.46252
IL18 interleukin 18 2.45893
SNAI2 snail family zinc finger 2 2.45646
GSTM3 glutathione S-transferase mu 3 (brain) 2.45321
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.45229
HLA-C major histocompatibility complex, class I, C 2.44869
PLD3 phospholipase D family, member 3 2.44731
CXCL9 chemokine (C-X-C motif) ligand 9 2.44548
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.44286
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 2.44135
GAA glucosidase, alpha; acid 2.44051
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.44032
PIR pirin (iron-binding nuclear protein) 2.43752
CAPN10 calpain 10 2.4363
SYNGR3 synaptogyrin 3 2.43558
S100A11 S100 calcium binding protein A11 2.42804
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.42798
KRT18 keratin 18, type I 2.42765
SLFN12 schlafen family member 12 2.42603
SUN2 Sad1 and UNC84 domain containing 2 2.41631
ZNF562 zinc finger protein 562 2.41291
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.40693
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.40561
PLTP phospholipid transfer protein 2.40549
TRIM62 tripartite motif containing 62 2.40098
SYNM synemin, intermediate filament protein 2.40081
SP140L SP140 nuclear body protein-like 2.39885
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.39753
IL2RA interleukin 2 receptor, alpha 2.39711
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.39586
SREBF1 sterol regulatory element binding transcription factor 1 2.3958
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.3934
CCNG2 cyclin G2 2.39125
IER5 immediate early response 5 2.386
NINJ1 ninjurin 1 2.38466
PLA2G2D phospholipase A2, group IID 2.3797
IGF2R insulin-like growth factor 2 receptor 2.37873
TP53I3 tumor protein p53 inducible protein 3 2.37869
CLDN4 claudin 4 2.37501
ANKRD10 ankyrin repeat domain 10 2.37145
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.37119
SH2D2A SH2 domain containing 2A 2.36877
ZNF219 zinc finger protein 219 2.36705
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.3638
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.35829
GM2A GM2 ganglioside activator 2.35586
ZNF197 zinc finger protein 197 2.35471
CTSV cathepsin V 2.34884
IPO13 importin 13 2.34692
TRAF4 TNF receptor-associated factor 4 2.34387
ZFC3H1 zinc finger, C3H1-type containing 2.34385
ZNF12 zinc finger protein 12 2.34358
PINK1 PTEN induced putative kinase 1 2.34115
PARP12 poly (ADP-ribose) polymerase family, member 12 2.33857
C4A complement component 4A (Rodgers blood group) 2.33432
ZNF140 zinc finger protein 140 2.33412
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.3341
DUSP2 dual specificity phosphatase 2 2.33157
NR1H3 nuclear receptor subfamily 1, group H, member 3 2.33142
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.3312
SLC75A1 solute carrier family 75 member 1 2.331
MRFAP1L1 Morf4 family associated protein 1-like 1 2.32943
NADSYN1 NAD synthetase 1 2.32874
SSH3 slingshot protein phosphatase 3 2.32694
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.32369
CORO2A coronin, actin binding protein, 2A 2.32239
KDM5C lysine (K)-specific demethylase 5C 2.31723
HSPB8 heat shock 22kDa protein 8 2.31715
DNASE1L1 deoxyribonuclease I-like 1 2.31359
CES2 carboxylesterase 2 2.31339
SFXN3 sideroflexin 3 2.31332
BBC3 BCL2 binding component 3 2.31306
DUSP6 dual specificity phosphatase 6 2.31248
SLAMF8 SLAM family member 8 2.31049
CEMIP2 cell migration inducing hyaluronidase 2 2.31002
TRIP6 thyroid hormone receptor interactor 6 2.30965
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.30913
EXOC2 exocyst complex component 2 2.30879
KDM7A lysine (K)-specific demethylase 7A 2.30511
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.30395
MMP9 matrix metallopeptidase 9 2.30087
TDG thymine-DNA glycosylase 2.29701
KRT5 keratin 5, type II 2.29304
WHRN whirlin 2.29053
ZNF446 zinc finger protein 446 2.29051
FUCA1 fucosidase, alpha-L- 1, tissue 2.2897
CCP110 centriolar coiled coil protein 110kDa 2.28934
AAMP angio-associated, migratory cell protein 2.2875
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.28555
EIF4A2 eukaryotic translation initiation factor 4A2 2.28458
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.28391
KCTD9 potassium channel tetramerization domain containing 9 2.28285
BCL2L2 BCL2-like 2 2.28122
ZBTB43 zinc finger and BTB domain containing 43 2.2786
CARD8 caspase recruitment domain family, member 8 2.27749
CD82 CD82 molecule 2.2717
ZBTB17 zinc finger and BTB domain containing 17 2.27144
TOLLIP toll interacting protein 2.26893
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.26588
ST18 suppression of tumorigenicity 18, zinc finger 2.26456
AIM2 absent in melanoma 2 2.26354
POMP proteasome maturation protein 2.26092
PNKP polynucleotide kinase 3'-phosphatase 2.2605
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.26044
RAB5IF RAB5 interacting factor 2.26035
NFS1 NFS1 cysteine desulfurase 2.25789
ST14 suppression of tumorigenicity 14 (colon carcinoma) 2.25705
TRIM22 tripartite motif containing 22 2.25424
ECM1 extracellular matrix protein 1 2.25068
DGKA diacylglycerol kinase, alpha 80kDa 2.25062
POLM polymerase (DNA directed), mu 2.24979
GBP2 guanylate binding protein 2, interferon-inducible 2.24547
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.24458
IL17RA interleukin 17 receptor A 2.24075
ACOT13 acyl-CoA thioesterase 13 2.23639
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.23207
NOTCH1 notch 1 2.22061
PLXNA1 plexin A1 2.21971
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.21727
PDCD6 programmed cell death 6 2.21651
KIZ kizuna centrosomal protein 2.21561
TLE3 transducin-like enhancer of split 3 2.2152
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.21463
DOK7 docking protein 7 2.21453
TRIM68 tripartite motif containing 68 2.21436
ACADVL acyl-CoA dehydrogenase, very long chain 2.21283
COQ8A coenzyme Q8A 2.2128
PKP3 plakophilin 3 2.21158
GADD45A growth arrest and DNA-damage-inducible, alpha 2.20909
FBN2 fibrillin 2 2.2054
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.19874
GAGE8 G antigen 8 2.19785
KRI1 KRI1 homolog (S. cerevisiae) 2.19703
SIGLEC15 sialic acid binding Ig-like lectin 15 2.19387
BAK1 BCL2-antagonist/killer 1 2.1934
TFE3 transcription factor binding to IGHM enhancer 3 2.19152
MAPK12 mitogen-activated protein kinase 12 2.19034
GBA1 glucosylceramidase beta 1 2.18956
GTPBP2 GTP binding protein 2 2.18931
CHMP1B charged multivesicular body protein 1B 2.18913
FRS2 fibroblast growth factor receptor substrate 2 2.18471
SLC67A1 solute carrier family 67 member 1 2.18452
JMJD7 jumonji domain containing 7 2.18292
KDSR 3-ketodihydrosphingosine reductase 2.17851
LOC102724428 serine/threonine-protein kinase SIK1 2.17773
RYR1 ryanodine receptor 1 (skeletal) 2.17725
AMZ2 archaelysin family metallopeptidase 2 2.17437
ZFTRAF1 zinc finger TRAF-type containing 1 2.17412
NRIP3 nuclear receptor interacting protein 3 2.17232
MBD1 methyl-CpG binding domain protein 1 2.16633
NEFH neurofilament, heavy polypeptide 2.16627
ELMO3 engulfment and cell motility 3 2.16602
BASP1 brain abundant, membrane attached signal protein 1 2.16501
KCTD7 potassium channel tetramerization domain containing 7 2.1577
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.15022
MYBPC1 myosin binding protein C, slow type 2.14772
RXRA retinoid X receptor, alpha 2.14629
KIAA0930 KIAA0930 2.14505
CST3 cystatin C 2.14403
ISL1 ISL LIM homeobox 1 2.14397
POPDC2 popeye domain containing 2 2.14233
EML2 echinoderm microtubule associated protein like 2 2.14138
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.14111
ARHGAP25 Rho GTPase activating protein 25 2.13666
CBX7 chromobox homolog 7 2.13571
PHF1 PHD finger protein 1 2.13454
LOC124904942 uncharacterized LOC124904942 2.13282
TSPO translocator protein (18kDa) 2.13136
SQSTM1 sequestosome 1 2.12776
RIC8A RIC8 guanine nucleotide exchange factor A 2.12658
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.11837
TMEM9B TMEM9 domain family, member B 2.11834
NFE2L1 nuclear factor, erythroid 2-like 1 2.11651
GHITM growth hormone inducible transmembrane protein 2.1121
CIC capicua transcriptional repressor 2.11206
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.10932
APLP1 amyloid beta (A4) precursor-like protein 1 2.10414
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 2.10072
TRAPPC6A trafficking protein particle complex 6A 2.10021
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.09955
TNNI2 troponin I type 2 (skeletal, fast) 2.09872
UNKL unkempt family zinc finger-like 2.09345
CES1 carboxylesterase 1 2.09135
ISCU iron-sulfur cluster assembly enzyme 2.09101
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.09076
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.08918
DLG5 discs, large homolog 5 (Drosophila) 2.08799
CYB561D2 cytochrome b561 family, member D2 2.08279
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.08085
KLF5 Kruppel-like factor 5 (intestinal) 2.07661
TP63 tumor protein p63 2.07603
HLA-B major histocompatibility complex, class I, B 2.07337
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 2.07311
IL2RB interleukin 2 receptor, beta 2.07156
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.06946
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.06915
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2.0675
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.0674
TNPO2 transportin 2 2.06713
RING1 ring finger protein 1 2.06632
TUBG2 tubulin, gamma 2 2.06273
TGM3 transglutaminase 3 2.06272
INO80B INO80 complex subunit B 2.0611
ALAS1 5'-aminolevulinate synthase 1 2.06055
FRMD4B FERM domain containing 4B 2.05972
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.05964
HHAT hedgehog acyltransferase 2.05887
GLRX glutaredoxin (thioltransferase) 2.05715
AIRIM AFG2 interacting ribosome maturation factor 2.05593
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 2.05561
AAGAB alpha- and gamma-adaptin binding protein 2.04992
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.04967
ZNF337 zinc finger protein 337 2.04929
SCHIP1 schwannomin interacting protein 1 2.04868
GRAMD4 GRAM domain containing 4 2.04797
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.04755
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.04508
NELFE negative elongation factor complex member E 2.04473
TKTL1 transketolase-like 1 2.04332
BMP1 bone morphogenetic protein 1 2.04246
CDC37L1 cell division cycle 37-like 1 2.04195
ZNF45 zinc finger protein 45 2.03967
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.03549
CCNL2 cyclin L2 2.03519
ATG4A autophagy related 4A, cysteine peptidase 2.03357
ZNF557 zinc finger protein 557 2.03324
BHLHE41 basic helix-loop-helix family, member e41 2.03224
ATG9A autophagy related 9A 2.03214
PNMA8A PNMA family member 8A 2.03195
MED22 mediator complex subunit 22 2.03161
MTRF1 mitochondrial translational release factor 1 2.03012
BTN2A1 butyrophilin, subfamily 2, member A1 2.02898
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.02846
USP33 ubiquitin specific peptidase 33 2.02845
HOXA5 homeobox A5 2.0269
ULK1 unc-51 like autophagy activating kinase 1 2.02494
BGLAP bone gamma-carboxyglutamate (gla) protein 2.02298
UBXN7 UBX domain protein 7 2.02253
HLA-F major histocompatibility complex, class I, F 2.02247
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.02091
LAMA5 laminin, alpha 5 2.02005
RAB33A RAB33A, member RAS oncogene family 2.01947
YBX3 Y box binding protein 3 2.01629
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 2.01414
IQSEC2 IQ motif and Sec7 domain 2 2.01343
FXR2 fragile X mental retardation, autosomal homolog 2 2.01225
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 2.01165
KYAT1 kynurenine aminotransferase 1 2.01099
ITGAV integrin, alpha V 2.01027
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.00942
CSTA cystatin A (stefin A) 2.00688
RPLP2 ribosomal protein, large, P2 2.00618
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough 2.00595
TUBA4A tubulin, alpha 4a 2.00454
PLCH2 phospholipase C, eta 2 2.00394
BSDC1 BSD domain containing 1 2.00366
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.0035
ZFYVE16 zinc finger, FYVE domain containing 16 2.00226
HABP4 hyaluronan binding protein 4 2.00088
PAQR6 progestin and adipoQ receptor family member VI 2.00082
SERTAD2 SERTA domain containing 2 2.00006

decreased expression

Symbol Name Standardized Value
PLIN2 perilipin 2 -8.49915
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -5.80228
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -5.47762
MCM3 minichromosome maintenance complex component 3 -5.42696
APOH apolipoprotein H (beta-2-glycoprotein I) -5.31439
APOA2 apolipoprotein A-II -4.89351
STMN1 stathmin 1 -4.81906
NFIL3 nuclear factor, interleukin 3 regulated -4.65362
PROM1 prominin 1 -4.64127
DERA deoxyribose-phosphate aldolase (putative) -4.52997
HADH hydroxyacyl-CoA dehydrogenase -4.49185
MCM6 minichromosome maintenance complex component 6 -4.33327
PPARG peroxisome proliferator-activated receptor gamma -4.29467
RSU1 Ras suppressor protein 1 -4.2805
HPRT1 hypoxanthine phosphoribosyltransferase 1 -4.27748
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.22555
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.19368
KIF15 kinesin family member 15 -4.16729
ATF6 activating transcription factor 6 -4.16584
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -4.09396
XYLT1 xylosyltransferase I -4.06913
PGM1 phosphoglucomutase 1 -4.02233
CZIB CXXC motif containing zinc binding protein -4.00558
RNASE4 ribonuclease, RNase A family, 4 -3.95618
TCF12 transcription factor 12 -3.89336
RGS7 regulator of G-protein signaling 7 -3.87549
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.8337
MCM10 minichromosome maintenance complex component 10 -3.79385
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.76557
PYCR1 pyrroline-5-carboxylate reductase 1 -3.74817
USP1 ubiquitin specific peptidase 1 -3.74473
CCNA2 cyclin A2 -3.717
STIL SCL/TAL1 interrupting locus -3.65926
TTK TTK protein kinase -3.59623
FBXO5 F-box protein 5 -3.56958
NUCB2 nucleobindin 2 -3.55925
RABL3 RAB, member of RAS oncogene family-like 3 -3.55822
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.51622
RHOBTB1 Rho-related BTB domain containing 1 -3.49461
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.45918
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.45094
SPC25 SPC25, NDC80 kinetochore complex component -3.44039
PHACTR2 phosphatase and actin regulator 2 -3.42097
ELOVL6 ELOVL fatty acid elongase 6 -3.41454
PCOLCE2 procollagen C-endopeptidase enhancer 2 -3.39993
PLK4 polo-like kinase 4 -3.39975
ZMYM4 zinc finger, MYM-type 4 -3.39333
SKA1 spindle and kinetochore associated complex subunit 1 -3.36403
HMGA2 high mobility group AT-hook 2 -3.35608
IL23A interleukin 23, alpha subunit p19 -3.3453
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -3.32978
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.3167
SEC31A SEC31 homolog A (S. cerevisiae) -3.31431
SELE selectin E -3.31189
ADNP2 ADNP homeobox 2 -3.31067
MCM5 minichromosome maintenance complex component 5 -3.29928
ARHGAP11A Rho GTPase activating protein 11A -3.28265
LBR lamin B receptor -3.28258
GIPC2 GIPC PDZ domain containing family, member 2 -3.28185
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -3.28046
KIF4A kinesin family member 4A -3.27675
ANKRD28 ankyrin repeat domain 28 -3.27525
MPC2 mitochondrial pyruvate carrier 2 -3.27295
RBM3 RNA binding motif (RNP1, RRM) protein 3 -3.2681
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -3.26658
SHCBP1 SHC SH2-domain binding protein 1 -3.25814
GPHN gephyrin -3.25555
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.25539
FAM171A1 family with sequence similarity 171, member A1 -3.24426
DPYSL2 dihydropyrimidinase-like 2 -3.2401
H2AZ2 H2A.Z variant histone 2 -3.20506
DET1 de-etiolated homolog 1 (Arabidopsis) -3.20298
ADRA2C adrenoceptor alpha 2C -3.19737
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.16679
IL17RB interleukin 17 receptor B -3.16629
S100P S100 calcium binding protein P -3.16552
AVEN apoptosis, caspase activation inhibitor -3.16327
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.13685
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.13541
CADPS2 Ca++-dependent secretion activator 2 -3.12849
AURKB aurora kinase B -3.12816
LRRC40 leucine rich repeat containing 40 -3.12384
NREP neuronal regeneration related protein -3.12173
PPIH peptidylprolyl isomerase H (cyclophilin H) -3.10492
NME4 NME/NM23 nucleoside diphosphate kinase 4 -3.10057
SIAH1 siah E3 ubiquitin protein ligase 1 -3.09938
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -3.09609
ARL2 ADP-ribosylation factor-like 2 -3.09548
KIF14 kinesin family member 14 -3.07741
LRRC59 leucine rich repeat containing 59 -3.07575
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.0719
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.06265
PLK1 polo-like kinase 1 -3.06211
FLT3 fms-related tyrosine kinase 3 -3.05074
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.04988
DUT deoxyuridine triphosphatase -3.04422
SOAT2 sterol O-acyltransferase 2 -3.02577
CENPE centromere protein E, 312kDa -3.01901
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -3.01777
PHKB phosphorylase kinase, beta -3.01357
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -3.00817
TTC27 tetratricopeptide repeat domain 27 -3.00525
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.00375
CCDC170 coiled-coil domain containing 170 -2.98567
ELP4 elongator acetyltransferase complex subunit 4 -2.98191
ANAPC15 anaphase promoting complex subunit 15 -2.97399
VASH2 vasohibin 2 -2.96511
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.96484
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.95407
KAT8 K(lysine) acetyltransferase 8 -2.93691
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.93196
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.93115
CENPI centromere protein I -2.92856
MYLK myosin light chain kinase -2.91585
FOXN2 forkhead box N2 -2.91509
KIF18A kinesin family member 18A -2.91131
UGP2 UDP-glucose pyrophosphorylase 2 -2.90783
PGM3 phosphoglucomutase 3 -2.90348
RBMX RNA binding motif protein, X-linked -2.89671
VRK1 vaccinia related kinase 1 -2.89609
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.89533
PRC1 protein regulator of cytokinesis 1 -2.8922
PECR peroxisomal trans-2-enoyl-CoA reductase -2.89188
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.88741
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.88603
MSRA methionine sulfoxide reductase A -2.87537
DCK deoxycytidine kinase -2.8695
RNF130 ring finger protein 130 -2.8625
SEPHS1 selenophosphate synthetase 1 -2.85967
L1TD1 LINE-1 type transposase domain containing 1 -2.85914
GPR176 G protein-coupled receptor 176 -2.85055
BIRC5 baculoviral IAP repeat containing 5 -2.84524
BRCA1 breast cancer 1, early onset -2.84212
TMEM97 transmembrane protein 97 -2.8368
CDC45 cell division cycle 45 -2.83621
RNF144A ring finger protein 144A -2.81524
H2AZ1 H2A.Z variant histone 1 -2.81522
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -2.81285
PFAS phosphoribosylformylglycinamidine synthase -2.81181
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.80574
CDC6 cell division cycle 6 -2.80469
ORC3 origin recognition complex, subunit 3 -2.80438
SMC3 structural maintenance of chromosomes 3 -2.80064
PSRC1 proline/serine-rich coiled-coil 1 -2.79919
DOCK2 dedicator of cytokinesis 2 -2.7947
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.79146
TF transferrin -2.78655
CDCA3 cell division cycle associated 3 -2.78407
RSRC1 arginine/serine-rich coiled-coil 1 -2.78217
ANO10 anoctamin 10 -2.7764
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.77183
DIAPH2 diaphanous-related formin 2 -2.77001
COPZ1 coatomer protein complex, subunit zeta 1 -2.76381
VPS26C VPS26 endosomal protein sorting factor C -2.76265
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.75773
FAM117A family with sequence similarity 117, member A -2.75722
GALK2 galactokinase 2 -2.75666
MSH2 mutS homolog 2 -2.75428
NLK nemo-like kinase -2.75089
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.74834
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.74396
ANG angiogenin, ribonuclease, RNase A family, 5 -2.74256
DAZAP1 DAZ associated protein 1 -2.74077
CLIC4 chloride intracellular channel 4 -2.73316
BCLAF1 BCL2-associated transcription factor 1 -2.73126
DHFR dihydrofolate reductase -2.72517
MCMBP minichromosome maintenance complex binding protein -2.72481
MFAP5 microfibrillar associated protein 5 -2.72338
KIF18B kinesin family member 18B -2.72265
MPC1 mitochondrial pyruvate carrier 1 -2.72025
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.71743
A1CF APOBEC1 complementation factor -2.71502
LTBP1 latent transforming growth factor beta binding protein 1 -2.68776
LRRC17 leucine rich repeat containing 17 -2.68315
EPS8 epidermal growth factor receptor pathway substrate 8 -2.67145
CD7 CD7 molecule -2.66988
OIP5 Opa interacting protein 5 -2.66942
GAS2 growth arrest-specific 2 -2.66805
MIS18BP1 MIS18 binding protein 1 -2.66118
HBG1 hemoglobin, gamma A -2.66074
LIMS2 LIM and senescent cell antigen-like domains 2 -2.66052
MCM7 minichromosome maintenance complex component 7 -2.65598
CENPB centromere protein B, 80kDa -2.64558
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.64437
TRIM24 tripartite motif containing 24 -2.63765
TIPIN TIMELESS interacting protein -2.63528
EMP2 epithelial membrane protein 2 -2.62911
CPED1 cadherin-like and PC-esterase domain containing 1 -2.62634
CCNB2 cyclin B2 -2.62097
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.62077
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.617
MYO10 myosin X -2.61342
SEC13 SEC13 homolog (S. cerevisiae) -2.61296
KIF23 kinesin family member 23 -2.60875
NASP nuclear autoantigenic sperm protein (histone-binding) -2.60515
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.60207
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.60125
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.59935
CALB1 calbindin 1, 28kDa -2.59742
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.59247
PEAK1 pseudopodium-enriched atypical kinase 1 -2.59062
ATAD5 ATPase family, AAA domain containing 5 -2.58867
ERCC6L excision repair cross-complementation group 6-like -2.58751
CRYM crystallin, mu -2.58733
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.58686
TCP1 t-complex 1 -2.58668
TRMT5 tRNA methyltransferase 5 -2.58641
HAVCR1 hepatitis A virus cellular receptor 1 -2.57995
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.57801
TASP1 taspase, threonine aspartase, 1 -2.57617
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.5752
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.57189
RNF2 ring finger protein 2 -2.56853
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.56732
NUP93 nucleoporin 93kDa -2.56593
NUP54 nucleoporin 54kDa -2.56326
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.55469
SEPTIN7 septin 7 -2.55137
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.54349
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.5423
FBF1 Fas (TNFRSF6) binding factor 1 -2.54122
ERI3 ERI1 exoribonuclease family member 3 -2.53861
SRSF3 serine/arginine-rich splicing factor 3 -2.53342
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.53308
HSPB2 heat shock 27kDa protein 2 -2.53289
NLRP4 NLR family, pyrin domain containing 4 -2.53077
NHP2 NHP2 ribonucleoprotein -2.53061
SKI SKI proto-oncogene -2.52981
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.52863
EHBP1 EH domain binding protein 1 -2.52811
ALDOC aldolase C, fructose-bisphosphate -2.52788
HAS2 hyaluronan synthase 2 -2.52422
CER1 cerberus 1, DAN family BMP antagonist -2.52182
E2F8 E2F transcription factor 8 -2.52048
PLEKHS1 pleckstrin homology domain containing, family S member 1 -2.51682
MUC7 mucin 7, secreted -2.51649
SF3B5 splicing factor 3b, subunit 5, 10kDa -2.51597
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.51377
CAMKMT calmodulin-lysine N-methyltransferase -2.51173
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.50991
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.50767
AHSG alpha-2-HS-glycoprotein -2.50532
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.50406
WDR76 WD repeat domain 76 -2.50263
STX2 syntaxin 2 -2.50247
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.50096
FHL5 four and a half LIM domains 5 -2.49999
FZD4 frizzled class receptor 4 -2.49976
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.49942
DCAF6 DDB1 and CUL4 associated factor 6 -2.49347
JRKL JRK-like -2.49314
IFT52 intraflagellar transport 52 -2.49177
USP21 ubiquitin specific peptidase 21 -2.49103
GPN1 GPN-loop GTPase 1 -2.48879
FXYD2 FXYD domain containing ion transport regulator 2 -2.48587
OXCT1 3-oxoacid CoA transferase 1 -2.48031
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.47431
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -2.47334
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.47149
NUP43 nucleoporin 43kDa -2.47079
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -2.46867
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.46854
SQLE squalene epoxidase -2.46801
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.46178
MPV17L-BMERB1 MPV17L-BMERB1 readthrough -2.46026
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -2.45612
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.45573
FBL fibrillarin -2.4549
CDC40 cell division cycle 40 -2.44977
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.44848
USP39 ubiquitin specific peptidase 39 -2.44763
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.4427
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.44191
KCNK2 potassium channel, two pore domain subfamily K, member 2 -2.44112
ORC6 origin recognition complex, subunit 6 -2.44102
CHL1 cell adhesion molecule L1-like -2.43864
PXMP2 peroxisomal membrane protein 2, 22kDa -2.434
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.42876
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.42875
UBA2 ubiquitin-like modifier activating enzyme 2 -2.42746
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.42505
FYN FYN proto-oncogene, Src family tyrosine kinase -2.42042
SYTL3 synaptotagmin-like 3 -2.41692
SNRPA small nuclear ribonucleoprotein polypeptide A -2.41449
MTMR2 myotubularin related protein 2 -2.41393
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.41336
FAIM Fas apoptotic inhibitory molecule -2.41269
POLK polymerase (DNA directed) kappa -2.40553
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -2.39993
RGN regucalcin -2.39701
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.39404
APOM apolipoprotein M -2.39375
ANK2 ankyrin 2, neuronal -2.38897
NBAS neuroblastoma amplified sequence -2.38424
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.38332
RAD51 RAD51 recombinase -2.38254
DENND10 DENN domain containing 10 -2.38213
NUSAP1 nucleolar and spindle associated protein 1 -2.38108
QPRT quinolinate phosphoribosyltransferase -2.38033
TFB1M transcription factor B1, mitochondrial -2.38033
HAT1 histone acetyltransferase 1 -2.37992
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.37871
PGLS 6-phosphogluconolactonase -2.37759
ANAPC1 anaphase promoting complex subunit 1 -2.3775
IPCEF1 interaction protein for cytohesin exchange factors 1 -2.37358
KIF2A kinesin heavy chain member 2A -2.37331
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.37075
ZEB1 zinc finger E-box binding homeobox 1 -2.36974
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.36851
LZTS3 leucine zipper, putative tumor suppressor family member 3 -2.36694
SYT2 synaptotagmin II -2.36676
DCTPP1 dCTP pyrophosphatase 1 -2.36633
CDT1 chromatin licensing and DNA replication factor 1 -2.3662
CENPQ centromere protein Q -2.35676
PROS1 protein S (alpha) -2.35567
ZNF587B zinc finger protein 587B -2.35216
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -2.35143
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.34777
CTPS2 CTP synthase 2 -2.34484
GPER1 G protein-coupled estrogen receptor 1 -2.34073
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.33999
MSH6 mutS homolog 6 -2.33545
EXOSC9 exosome component 9 -2.33302
PPIB peptidylprolyl isomerase B (cyclophilin B) -2.33257
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -2.33101
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -2.33039
CDC20 cell division cycle 20 -2.3301
NCK2 NCK adaptor protein 2 -2.32384
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.32242
PRIM1 primase, DNA, polypeptide 1 (49kDa) -2.31762
SPAG5 sperm associated antigen 5 -2.31298
NUP205 nucleoporin 205kDa -2.3127
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.31048
AKAP12 A kinase (PRKA) anchor protein 12 -2.31046
RBBP9 retinoblastoma binding protein 9 -2.31037
CENPA centromere protein A -2.30927
EML4 echinoderm microtubule associated protein like 4 -2.30847
FANCC Fanconi anemia, complementation group C -2.30721
VCAM1 vascular cell adhesion molecule 1 -2.30662
ZMYM1 zinc finger, MYM-type 1 -2.30474
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.30375
NPR2 natriuretic peptide receptor 2 -2.30167
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -2.30049
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.30047
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.29898
SRFBP1 serum response factor binding protein 1 -2.29895
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.29473
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.29184
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.29017
CLDN10 claudin 10 -2.28635
PCCA propionyl CoA carboxylase, alpha polypeptide -2.28423
HSPA14 heat shock 70kDa protein 14 -2.28325
AP3B1 adaptor-related protein complex 3, beta 1 subunit -2.28136
COG7 component of oligomeric golgi complex 7 -2.28093
PIMREG PICALM interacting mitotic regulator -2.27993
CXCL6 chemokine (C-X-C motif) ligand 6 -2.279
FOXJ3 forkhead box J3 -2.27846
CASP8AP2 caspase 8 associated protein 2 -2.27738
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.27419
PARPBP PARP1 binding protein -2.2738
STAG2 stromal antigen 2 -2.26786
ASGR1 asialoglycoprotein receptor 1 -2.26734
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -2.26554
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.26534
NLGN4X neuroligin 4, X-linked -2.25016
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -2.24719
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.24621
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.24076
MTREX Mtr4 exosome RNA helicase -2.23455
CHEK1 checkpoint kinase 1 -2.23335
SOSTDC1 sclerostin domain containing 1 -2.23249
SEPTIN11 septin 11 -2.23072
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.23071
FBLN5 fibulin 5 -2.22902
S100G S100 calcium binding protein G -2.22901
MORF4L1 mortality factor 4 like 1 -2.22731
SMC5 structural maintenance of chromosomes 5 -2.22594
MIS18A MIS18 kinetochore protein A -2.22518
ICE2 interactor of little elongation complex ELL subunit 2 -2.22179
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.22011
GLDC glycine dehydrogenase (decarboxylating) -2.21983
PTPRK protein tyrosine phosphatase, receptor type, K -2.21958
MRPL23 mitochondrial ribosomal protein L23 -2.21944
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.21915
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.21787
RAB23 RAB23, member RAS oncogene family -2.21403
NOX4 NADPH oxidase 4 -2.21276
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -2.21201
CLOCK clock circadian regulator -2.20541
AMT aminomethyltransferase -2.20254
PAH phenylalanine hydroxylase -2.19915
S100A1 S100 calcium binding protein A1 -2.19831
LYZ lysozyme -2.19819
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.19761
WRN Werner syndrome, RecQ helicase-like -2.19648
ATG5 autophagy related 5 -2.19541
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -2.19164
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -2.18975
NCOA3 nuclear receptor coactivator 3 -2.1855
PHYH phytanoyl-CoA 2-hydroxylase -2.18515
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.1847
CEP350 centrosomal protein 350kDa -2.18466
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) -2.18289
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.1827
DONSON downstream neighbor of SON -2.18217
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.18036
VSNL1 visinin-like 1 -2.17878
EIF3K eukaryotic translation initiation factor 3, subunit K -2.17856
KHK ketohexokinase (fructokinase) -2.17839
MYO1D myosin ID -2.17599
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.17486
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.17383
FCF1 FCF1 rRNA-processing protein -2.17317
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.17301
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.17216
INTS14 integrator complex subunit 14 -2.17207
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.17051
LIME1 Lck interacting transmembrane adaptor 1 -2.16978
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.16956
TRA2B transformer 2 beta homolog (Drosophila) -2.16716
FAM184A family with sequence similarity 184, member A -2.16634
CLEC1A C-type lectin domain family 1, member A -2.16522
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -2.16332
EDNRB endothelin receptor type B -2.16296
ZSCAN5A zinc finger and SCAN domain containing 5A -2.16249
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.16002
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.15894
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -2.15777
NANOG Nanog homeobox -2.15753
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.15382
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.15216
PDCD5 programmed cell death 5 -2.15182
CEP57 centrosomal protein 57kDa -2.15166
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.14989
RBM14-RBM4 RBM14-RBM4 readthrough -2.14907
NUP133 nucleoporin 133kDa -2.14735
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.14683
ASB13 ankyrin repeat and SOCS box containing 13 -2.14648
BLM Bloom syndrome, RecQ helicase-like -2.14589
MKI67 marker of proliferation Ki-67 -2.14587
SRSF2 serine/arginine-rich splicing factor 2 -2.14508
KIF2C kinesin family member 2C -2.14447
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.14433
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -2.14127
NCAPD2 non-SMC condensin I complex, subunit D2 -2.14038
DHRS7B dehydrogenase/reductase (SDR family) member 7B -2.1364
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.13571
COL5A3 collagen, type V, alpha 3 -2.13135
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.13069
CDK4 cyclin-dependent kinase 4 -2.12974
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.12707
SF3A2 splicing factor 3a, subunit 2, 66kDa -2.12402
BSPRY B-box and SPRY domain containing -2.12094
ACSS3 acyl-CoA synthetase short-chain family member 3 -2.12031
MRPL19 mitochondrial ribosomal protein L19 -2.12018
CTSG cathepsin G -2.11966
RAD51AP1 RAD51 associated protein 1 -2.11848
MEF2A myocyte enhancer factor 2A -2.11778
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -2.1167
ANXA6 annexin A6 -2.11656
C4BPA complement component 4 binding protein, alpha -2.11562
RFC2 replication factor C (activator 1) 2, 40kDa -2.11189
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.11183
PALMD palmdelphin -2.11165
PBK PDZ binding kinase -2.1114
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.11116
SMYD3 SET and MYND domain containing 3 -2.11074
KIAA0586 KIAA0586 -2.11072
WDR18 WD repeat domain 18 -2.10746
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.10479
SAE1 SUMO1 activating enzyme subunit 1 -2.10201
RPA3 replication protein A3, 14kDa -2.10153
CD207 CD207 molecule, langerin -2.09986
TM4SF5 transmembrane 4 L six family member 5 -2.09853
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.09546
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.09289
MCM4 minichromosome maintenance complex component 4 -2.09138
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -2.09079
EXO1 exonuclease 1 -2.08836
RNFT2 ring finger protein, transmembrane 2 -2.08768
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.08342
BEX2 brain expressed X-linked 2 -2.08159
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -2.08022
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.07932
MPZL1 myelin protein zero-like 1 -2.07423
KL klotho -2.0723
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -2.07064
NDC1 NDC1 transmembrane nucleoporin -2.06724
ELAVL1 ELAV like RNA binding protein 1 -2.06724
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.06628
MBNL3 muscleblind-like splicing regulator 3 -2.0642
FABP7 fatty acid binding protein 7, brain -2.06375
TSPAN7 tetraspanin 7 -2.0633
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.06239
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.0618
MDN1 MDN1, midasin homolog (yeast) -2.06017
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.05846
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.05242
CENPF centromere protein F, 350/400kDa -2.05128
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.05114
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.04978
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -2.04839
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -2.04572
SFRP4 secreted frizzled-related protein 4 -2.04492
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.04398
IMMT inner membrane protein, mitochondrial -2.04367
SOCS6 suppressor of cytokine signaling 6 -2.04354
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.04308
FGFR4 fibroblast growth factor receptor 4 -2.04265
INTS9 integrator complex subunit 9 -2.03906
ADH6 alcohol dehydrogenase 6 (class V) -2.03491
SRBD1 S1 RNA binding domain 1 -2.03478
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 -2.03275
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.0303
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -2.0302
TOP2A topoisomerase (DNA) II alpha 170kDa -2.02812
ZNF609 zinc finger protein 609 -2.02765
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.02612
RANBP17 RAN binding protein 17 -2.02524
MGLL monoglyceride lipase -2.02508
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -2.02384
CYB5A cytochrome b5 type A (microsomal) -2.02175
GLYAT glycine-N-acyltransferase -2.01971
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.0176
ZNF286A zinc finger protein 286A -2.01468
MAOB monoamine oxidase B -2.01339
ANAPC10 anaphase promoting complex subunit 10 -2.00962
CDK2 cyclin-dependent kinase 2 -2.00936
CS citrate synthase -2.00903
ACTG2 actin, gamma 2, smooth muscle, enteric -2.00776
DPPA4 developmental pluripotency associated 4 -2.0074
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -2.00634
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -2.00426
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.00385
FAR2 fatty acyl CoA reductase 2 -2.00364
SETD2 SET domain containing 2 -2.00299
ILK integrin-linked kinase -2.00282
VCAN versican -2.00165