CRCGN015_HEPG2_48H:M24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitropyrene 11.33 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

389 genes differentially expressed following the CRCGN015_HEPG2_48H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 7.21113
ABHD4 abhydrolase domain containing 4 6.68102
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 6.19642
INPP1 inositol polyphosphate-1-phosphatase 5.50987
MICALL1 MICAL-like 1 5.32139
LRP10 low density lipoprotein receptor-related protein 10 5.26623
RALGDS ral guanine nucleotide dissociation stimulator 5.26178
BLCAP bladder cancer associated protein 5.20649
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.05292
DDB2 damage-specific DNA binding protein 2, 48kDa 4.7023
PHLDA3 pleckstrin homology-like domain, family A, member 3 4.64662
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 4.59658
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 4.47388
FRS2 fibroblast growth factor receptor substrate 2 4.37148
TUBB6 tubulin, beta 6 class V 4.36865
TIGAR TP53 induced glycolysis regulatory phosphatase 4.35143
FDXR ferredoxin reductase 4.27064
SESN1 sestrin 1 3.90885
ZMAT3 zinc finger, matrin-type 3 3.84925
CDIP1 cell death-inducing p53 target 1 3.75452
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 3.73085
HEBP1 heme binding protein 1 3.6586
GPC1 glypican 1 3.62102
EPS8L2 EPS8-like 2 3.61524
EPHA2 EPH receptor A2 3.61071
FOSL1 FOS-like antigen 1 3.58356
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.45868
THSD1 thrombospondin, type I, domain containing 1 3.44191
NSUN3 NOP2/Sun domain family, member 3 3.4347
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.39484
ZNF79 zinc finger protein 79 3.38893
ADGRG1 adhesion G protein-coupled receptor G1 3.31323
IER3 immediate early response 3 3.30346
FASN fatty acid synthase 3.27713
STOM stomatin 3.27026
CCDC90B coiled-coil domain containing 90B 3.2099
CCDC86 coiled-coil domain containing 86 3.17285
BTG2 BTG family, member 2 3.15618
COL17A1 collagen, type XVII, alpha 1 3.13098
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.09198
EDN2 endothelin 2 2.98439
UFM1 ubiquitin-fold modifier 1 2.9519
SQSTM1 sequestosome 1 2.88106
XPC xeroderma pigmentosum, complementation group C 2.87448
MKNK2 MAP kinase interacting serine/threonine kinase 2 2.85296
TESK1 testis-specific kinase 1 2.82915
PTGES prostaglandin E synthase 2.79997
IL4R interleukin 4 receptor 2.78508
GALNS galactosamine (N-acetyl)-6-sulfatase 2.78041
DUSP14 dual specificity phosphatase 14 2.76176
MAN1B1 mannosidase, alpha, class 1B, member 1 2.75061
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.73974
SCRIB scribbled planar cell polarity protein 2.7194
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.71798
SIRT7 sirtuin 7 2.68496
SURF2 surfeit 2 2.68
CHIC2 cysteine-rich hydrophobic domain 2 2.67316
STEAP3 STEAP family member 3, metalloreductase 2.67293
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.65854
TBK1 TANK-binding kinase 1 2.65051
CXCL13 chemokine (C-X-C motif) ligand 13 2.64063
TBC1D2 TBC1 domain family, member 2 2.60384
SPATA20 spermatogenesis associated 20 2.59811
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.58582
TP53I3 tumor protein p53 inducible protein 3 2.5762
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.57327
AMZ2 archaelysin family metallopeptidase 2 2.56635
GPR87 G protein-coupled receptor 87 2.54912
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.53785
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.5286
TRIB1 tribbles pseudokinase 1 2.52816
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.52772
TERF2IP telomeric repeat binding factor 2, interacting protein 2.52654
SCPEP1 serine carboxypeptidase 1 2.51655
TKTL1 transketolase-like 1 2.51311
TXLNA taxilin alpha 2.50458
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.50325
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.50124
ADAT1 adenosine deaminase, tRNA-specific 1 2.498
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.48645
PRKCD protein kinase C, delta 2.483
HSPB1 heat shock 27kDa protein 1 2.48021
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.47253
RRAGC Ras-related GTP binding C 2.4633
TOR4A torsin family 4, member A 2.4532
GADD45A growth arrest and DNA-damage-inducible, alpha 2.44968
CD8A CD8a molecule 2.44962
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.44524
DRAM1 DNA-damage regulated autophagy modulator 1 2.44454
ANXA8L1 annexin A8-like 1 2.43846
SKIC2 SKI2 subunit of superkiller complex 2.43697
STAT1 signal transducer and activator of transcription 1, 91kDa 2.43347
RIOK3 RIO kinase 3 2.4265
REXO2 RNA exonuclease 2 2.42535
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.41839
CEL carboxyl ester lipase 2.41691
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.40374
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.39407
SDC4 syndecan 4 2.36945
TOB1 transducer of ERBB2, 1 2.36219
CXCL9 chemokine (C-X-C motif) ligand 9 2.34955
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.34331
STARD5 StAR-related lipid transfer (START) domain containing 5 2.34282
COL4A5 collagen, type IV, alpha 5 2.34036
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.33445
ITPKC inositol-trisphosphate 3-kinase C 2.32603
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.32097
ZNF211 zinc finger protein 211 2.31749
BAX BCL2-associated X protein 2.31402
TRIM22 tripartite motif containing 22 2.30624
MAGEA11 melanoma antigen family A11 2.28169
NADSYN1 NAD synthetase 1 2.28134
SLC75A1 solute carrier family 75 member 1 2.27885
TDP2 tyrosyl-DNA phosphodiesterase 2 2.2767
CD247 CD247 molecule 2.265
DGKA diacylglycerol kinase, alpha 80kDa 2.25156
HSPA4L heat shock 70kDa protein 4-like 2.25153
GRN granulin 2.24118
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.23541
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.22856
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.21157
MDFI MyoD family inhibitor 2.21049
IL18 interleukin 18 2.2064
DUOX2 dual oxidase 2 2.19992
DOK7 docking protein 7 2.19819
SOWAHC sosondowah ankyrin repeat domain family member C 2.19539
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.19287
CES2 carboxylesterase 2 2.1875
IFNG interferon, gamma 2.17246
CLCA2 chloride channel accessory 2 2.17091
RNPEP arginyl aminopeptidase (aminopeptidase B) 2.1557
EGR1 early growth response 1 2.15254
XYLT2 xylosyltransferase II 2.14657
CSRNP2 cysteine-serine-rich nuclear protein 2 2.14493
IGF2R insulin-like growth factor 2 receptor 2.14475
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.14132
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 2.13263
PERP PERP, TP53 apoptosis effector 2.13185
RIC8A RIC8 guanine nucleotide exchange factor A 2.13001
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.12185
ELL2 elongation factor, RNA polymerase II, 2 2.10986
SFTPA2 surfactant protein A2 2.10935
RAB38 RAB38, member RAS oncogene family 2.10933
ZBTB17 zinc finger and BTB domain containing 17 2.10441
KRI1 KRI1 homolog (S. cerevisiae) 2.09541
POMP proteasome maturation protein 2.09294
LAP3 leucine aminopeptidase 3 2.09037
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.08701
GSDME gasdermin E 2.08646
RNF44 ring finger protein 44 2.0773
PLCH2 phospholipase C, eta 2 2.07492
MICALL2 MICAL-like 2 2.07407
MBD1 methyl-CpG binding domain protein 1 2.07014
GABARAPL1 GABA(A) receptor-associated protein like 1 2.06872
COL7A1 collagen, type VII, alpha 1 2.06388
PFN2 profilin 2 2.06112
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.05687
GLRX2 glutaredoxin 2 2.05586
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.05164
ITGAV integrin, alpha V 2.04356
IPO13 importin 13 2.03558
KREMEN2 kringle containing transmembrane protein 2 2.03458
MEGF6 multiple EGF-like-domains 6 2.03235
AVPI1 arginine vasopressin-induced 1 2.02665
IL17RA interleukin 17 receptor A 2.02572
FAM131A family with sequence similarity 131, member A 2.02561
CHD8 chromodomain helicase DNA binding protein 8 2.02452
MAP7D1 MAP7 domain containing 1 2.02404
PLEC plectin 2.02401
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.01964
LAMB3 laminin, beta 3 2.01963
KEAP1 kelch-like ECH-associated protein 1 2.01835
SNAI2 snail family zinc finger 2 2.01741
THUMPD2 THUMP domain containing 2 2.01713
AEN apoptosis enhancing nuclease 2.00747
KRT32 keratin 32, type I 2.00684
PHF1 PHD finger protein 1 2.0058
GJB5 gap junction protein, beta 5, 31.1kDa 2.00533
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.00523
TUBG2 tubulin, gamma 2 2.00496

decreased expression

Symbol Name Standardized Value
PECR peroxisomal trans-2-enoyl-CoA reductase -6.21999
MCM3 minichromosome maintenance complex component 3 -5.15646
PROM1 prominin 1 -4.25383
APOH apolipoprotein H (beta-2-glycoprotein I) -4.17217
APOA2 apolipoprotein A-II -3.89695
NFIL3 nuclear factor, interleukin 3 regulated -3.5408
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.52508
HADH hydroxyacyl-CoA dehydrogenase -3.44424
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.43421
THAP11 THAP domain containing 11 -3.42945
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.41749
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -3.33637
PYCR1 pyrroline-5-carboxylate reductase 1 -3.32836
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.18532
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.18269
MCM6 minichromosome maintenance complex component 6 -3.13207
CZIB CXXC motif containing zinc binding protein -3.11705
NUP93 nucleoporin 93kDa -3.10805
CCNA2 cyclin A2 -3.06933
CADPS2 Ca++-dependent secretion activator 2 -3.01042
RNASE4 ribonuclease, RNase A family, 4 -3.00374
TASP1 taspase, threonine aspartase, 1 -2.99578
MCM5 minichromosome maintenance complex component 5 -2.98201
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.91642
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.91361
HEATR1 HEAT repeat containing 1 -2.91154
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -2.90906
NUCB2 nucleobindin 2 -2.90655
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.87457
XYLT1 xylosyltransferase I -2.81795
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.81532
CHL1 cell adhesion molecule L1-like -2.81244
RGS7 regulator of G-protein signaling 7 -2.80939
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.79395
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.77364
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.77099
MAOB monoamine oxidase B -2.76383
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.76009
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.75865
USP1 ubiquitin specific peptidase 1 -2.75371
LBR lamin B receptor -2.74976
ATF6 activating transcription factor 6 -2.74569
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.73888
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.69528
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.69317
HOOK1 hook microtubule-tethering protein 1 -2.68422
DCAF6 DDB1 and CUL4 associated factor 6 -2.63887
RHOBTB1 Rho-related BTB domain containing 1 -2.62931
KIF4A kinesin family member 4A -2.62012
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.60609
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.60059
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.58147
FBXO5 F-box protein 5 -2.57256
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.55578
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.55341
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.54117
RSU1 Ras suppressor protein 1 -2.53743
PEX11A peroxisomal biogenesis factor 11 alpha -2.5313
ELOVL6 ELOVL fatty acid elongase 6 -2.53117
MPC2 mitochondrial pyruvate carrier 2 -2.51333
MCM10 minichromosome maintenance complex component 10 -2.50944
STIL SCL/TAL1 interrupting locus -2.5018
ALDOC aldolase C, fructose-bisphosphate -2.50168
KIF15 kinesin family member 15 -2.49061
NCK2 NCK adaptor protein 2 -2.48731
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.48149
TLR5 toll-like receptor 5 -2.48081
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.47248
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.4673
C2CD5 C2 calcium-dependent domain containing 5 -2.45585
LRRC17 leucine rich repeat containing 17 -2.44691
PSRC1 proline/serine-rich coiled-coil 1 -2.44678
FBL fibrillarin -2.44678
SPC25 SPC25, NDC80 kinetochore complex component -2.44249
ELP4 elongator acetyltransferase complex subunit 4 -2.43889
NUP133 nucleoporin 133kDa -2.43108
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.42958
NCOA3 nuclear receptor coactivator 3 -2.41983
PLK1 polo-like kinase 1 -2.40384
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.39471
CDT1 chromatin licensing and DNA replication factor 1 -2.39271
PRR5L proline rich 5 like -2.39232
MYLK myosin light chain kinase -2.38583
DHFR dihydrofolate reductase -2.38266
GJB1 gap junction protein, beta 1, 32kDa -2.37934
BSPRY B-box and SPRY domain containing -2.37598
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.37474
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.37361
TBP TATA box binding protein -2.3692
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.36846
RNF144A ring finger protein 144A -2.36487
PGM3 phosphoglucomutase 3 -2.36379
TSPAN7 tetraspanin 7 -2.35706
PGM1 phosphoglucomutase 1 -2.35517
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.3542
CASP8AP2 caspase 8 associated protein 2 -2.34856
TTK TTK protein kinase -2.34521
FAM171A1 family with sequence similarity 171, member A1 -2.34341
EXTL2 exostosin-like glycosyltransferase 2 -2.33768
DET1 de-etiolated homolog 1 (Arabidopsis) -2.33489
VRK1 vaccinia related kinase 1 -2.33431
TRIM6-TRIM34 TRIM6-TRIM34 readthrough -2.32859
RBP1 retinol binding protein 1, cellular -2.31179
PPARG peroxisome proliferator-activated receptor gamma -2.30726
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.30602
IFT52 intraflagellar transport 52 -2.29844
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.29715
STMN1 stathmin 1 -2.29413
OBI1 ORC ubiquitin ligase 1 -2.29251
GYPC glycophorin C (Gerbich blood group) -2.29214
EDAR ectodysplasin A receptor -2.28977
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.28945
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.28259
CYB5A cytochrome b5 type A (microsomal) -2.28247
MIS18A MIS18 kinetochore protein A -2.27845
GIPC2 GIPC PDZ domain containing family, member 2 -2.27472
ITSN1 intersectin 1 (SH3 domain protein) -2.27469
GPHN gephyrin -2.2675
CDC6 cell division cycle 6 -2.266
NUP205 nucleoporin 205kDa -2.2568
MTREX Mtr4 exosome RNA helicase -2.24326
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.23966
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 -2.23826
CENPE centromere protein E, 312kDa -2.23442
MBD5 methyl-CpG binding domain protein 5 -2.23206
LTBP1 latent transforming growth factor beta binding protein 1 -2.22513
PFAS phosphoribosylformylglycinamidine synthase -2.22293
CDC45 cell division cycle 45 -2.21709
CENPB centromere protein B, 80kDa -2.21348
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.2082
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.20516
PRC1 protein regulator of cytokinesis 1 -2.20273
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.20196
IPCEF1 interaction protein for cytohesin exchange factors 1 -2.20164
CDC20 cell division cycle 20 -2.19966
OIP5 Opa interacting protein 5 -2.19665
SYT2 synaptotagmin II -2.19552
SOAT2 sterol O-acyltransferase 2 -2.19359
NHLRC2 NHL repeat containing 2 -2.18532
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.18257
AHSG alpha-2-HS-glycoprotein -2.18089
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -2.16974
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.1616
NR2F2 nuclear receptor subfamily 2, group F, member 2 -2.15977
KAT8 K(lysine) acetyltransferase 8 -2.15752
FABP7 fatty acid binding protein 7, brain -2.15492
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.15441
CCDC170 coiled-coil domain containing 170 -2.15
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.14718
CLOCK clock circadian regulator -2.14048
PHYH phytanoyl-CoA 2-hydroxylase -2.13668
SAE1 SUMO1 activating enzyme subunit 1 -2.1362
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.13143
AVEN apoptosis, caspase activation inhibitor -2.13128
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.13016
CETN3 centrin, EF-hand protein, 3 -2.12906
RABL3 RAB, member of RAS oncogene family-like 3 -2.12812
LY86 lymphocyte antigen 86 -2.12722
ZNF587B zinc finger protein 587B -2.12703
LZTS3 leucine zipper, putative tumor suppressor family member 3 -2.12693
UBA2 ubiquitin-like modifier activating enzyme 2 -2.1241
RTN3 reticulon 3 -2.12061
METTL9 methyltransferase like 9 -2.11973
NASP nuclear autoantigenic sperm protein (histone-binding) -2.11771
MPV17L-BMERB1 MPV17L-BMERB1 readthrough -2.11708
SNX5 sorting nexin 5 -2.11676
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.11591
PLK4 polo-like kinase 4 -2.11246
NPTX1 neuronal pentraxin I -2.10872
FEN1 flap structure-specific endonuclease 1 -2.10791
HSDL2 hydroxysteroid dehydrogenase like 2 -2.10489
CXCL6 chemokine (C-X-C motif) ligand 6 -2.10462
LAMP5 lysosomal-associated membrane protein family, member 5 -2.1046
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.10313
DENND5A DENN/MADD domain containing 5A -2.10113
DMAC2L distal membrane arm assembly component 2 like -2.10078
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.10024
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 -2.09809
NANOG Nanog homeobox -2.0914
ANXA6 annexin A6 -2.08966
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.08824
ADGRE3 adhesion G protein-coupled receptor E3 -2.08501
SEPHS1 selenophosphate synthetase 1 -2.08111
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -2.07911
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.07738
BRCA1 breast cancer 1, early onset -2.06982
AKR1D1 aldo-keto reductase family 1, member D1 -2.06861
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.06637
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.06102
RNF130 ring finger protein 130 -2.05355
DPYSL2 dihydropyrimidinase-like 2 -2.05201
SIAH1 siah E3 ubiquitin protein ligase 1 -2.04645
MCMBP minichromosome maintenance complex binding protein -2.04587
NLRP4 NLR family, pyrin domain containing 4 -2.04065
S100A1 S100 calcium binding protein A1 -2.03752
RFC2 replication factor C (activator 1) 2, 40kDa -2.03636
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.03422
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.02657
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.02495
ASRGL1 asparaginase like 1 -2.02433
PPA2 pyrophosphatase (inorganic) 2 -2.01986
GAS2 growth arrest-specific 2 -2.01621
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.01416
RBMX RNA binding motif protein, X-linked -2.01409
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.01111
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.00824
DCK deoxycytidine kinase -2.00604
TRMT61B tRNA methyltransferase 61B -2.00537
POLK polymerase (DNA directed) kappa -2.0024