CRCGN015_HEPG2_48H:N01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 104.79 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_HEPG2_48H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 6.81438
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.27391
CXCL2 chemokine (C-X-C motif) ligand 2 3.26562
SCRN1 secernin 1 2.80299
MICALL1 MICAL-like 1 2.39979
RIDA reactive intermediate imine deaminase A homolog 2.29372
NKX2-2 NK2 homeobox 2 2.28438
NPY1R neuropeptide Y receptor Y1 2.19784
GLCE glucuronic acid epimerase 2.09111

decreased expression

Symbol Name Standardized Value
PROM1 prominin 1 -3.60791
ETFB electron-transfer-flavoprotein, beta polypeptide -2.7861
MKNK1 MAP kinase interacting serine/threonine kinase 1 -2.6942
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.62783
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.59328
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.45234
MX2 MX dynamin-like GTPase 2 -2.41272
PECR peroxisomal trans-2-enoyl-CoA reductase -2.39954
STXBP3 syntaxin binding protein 3 -2.26256
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.17501
HDAC7 histone deacetylase 7 -2.05842
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.04596