CRCGN015_HEPG2_48H:N03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description propyleneimine 11.64 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

48 genes differentially expressed following the CRCGN015_HEPG2_48H:N03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRKCH protein kinase C, eta 4.67579
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.36086
FZD7 frizzled class receptor 7 3.19551
DENND2D DENN/MADD domain containing 2D 2.79337
SYNE2 spectrin repeat containing, nuclear envelope 2 2.69573
APEH acylaminoacyl-peptide hydrolase 2.36196
TATDN2 TatD DNase domain containing 2 2.09154
TSPAN13 tetraspanin 13 2.07228
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.04471
NELL2 NEL-like 2 (chicken) 2.04245
LIPG lipase, endothelial 2.03895
AMDHD2 amidohydrolase domain containing 2 2.03101

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -5.65912
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -5.60931
ENOPH1 enolase-phosphatase 1 -4.44106
COPS4 COP9 signalosome subunit 4 -3.48839
RALB v-ral simian leukemia viral oncogene homolog B -3.33658
NCK1 NCK adaptor protein 1 -3.00085
VDAC1 voltage-dependent anion channel 1 -2.92474
INF2 inverted formin, FH2 and WH2 domain containing -2.87158
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.54438
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.48456
CXADR coxsackie virus and adenovirus receptor -2.31642
TWIST1 twist family bHLH transcription factor 1 -2.27142
STAT5A signal transducer and activator of transcription 5A -2.26948
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.25207
GFER growth factor, augmenter of liver regeneration -2.24082
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.23816
DCTD dCMP deaminase -2.22085
PDCL3 phosducin-like 3 -2.22003
SLAMF1 signaling lymphocytic activation molecule family member 1 -2.18295
SIRT2 sirtuin 2 -2.17401
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -2.13755
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 -2.12533
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.11237
PADI1 peptidyl arginine deiminase, type I -2.08786
OR1D2 olfactory receptor, family 1, subfamily D, member 2 -2.06734
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -2.06664
TMSB4Y thymosin beta 4, Y-linked -2.0663
DMAP1 DNA methyltransferase 1 associated protein 1 -2.05939
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -2.05762
SEC31A SEC31 homolog A (S. cerevisiae) -2.04518
KLHL25 kelch-like family member 25 -2.04284
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.03786
INKA2 inka box actin regulator 2 -2.01724
KLK1 kallikrein 1 -2.01342
IQCB1 IQ motif containing B1 -2.01323
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.00459