CRCGN015_HEPG2_48H:N04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 99.3 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

46 genes differentially expressed following the CRCGN015_HEPG2_48H:N04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.30582
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.96145
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.38885
CASP10 caspase 10, apoptosis-related cysteine peptidase 3.01241
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.78965
FCGBP Fc fragment of IgG binding protein 2.58933
NALF2 NALCN channel auxiliary factor 2 2.57563
GTPBP8 GTP-binding protein 8 (putative) 2.56783
TRAT1 T cell receptor associated transmembrane adaptor 1 2.52775
CHI3L2 chitinase 3-like 2 2.44965
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 2.40825
DND1 DND microRNA-mediated repression inhibitor 1 2.36625
TSHR thyroid stimulating hormone receptor 2.35377
G6PC2 glucose-6-phosphatase, catalytic, 2 2.34322
TMEM109 transmembrane protein 109 2.3362
CD8A CD8a molecule 2.31721
PHF20L1 PHD finger protein 20-like 1 2.31021
HYOU1 hypoxia up-regulated 1 2.30931
DCHS2 dachsous cadherin-related 2 2.27342
CDC25A cell division cycle 25A 2.25197
DRP2 dystrophin related protein 2 2.22927
RRH retinal pigment epithelium-derived rhodopsin homolog 2.22082
CD1B CD1b molecule 2.21075
KIF5A kinesin family member 5A 2.20947
ERCC4 excision repair cross-complementation group 4 2.18421
LPAR6 lysophosphatidic acid receptor 6 2.16489
ZNF280A zinc finger protein 280A 2.15236
PDZK1IP1 PDZK1 interacting protein 1 2.11314
ASIC1 acid sensing (proton gated) ion channel 1 2.098
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.08731
LAX1 lymphocyte transmembrane adaptor 1 2.06286
MAN1C1 mannosidase, alpha, class 1C, member 1 2.05495
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.05298
TRIM66 tripartite motif containing 66 2.04226
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.02342
DIPK2B divergent protein kinase domain 2B 2.01316
INHBC inhibin, beta C 2.00035

decreased expression

Symbol Name Standardized Value
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.81023
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.10528
SLC35F2 solute carrier family 35, member F2 -3.23047
PDLIM1 PDZ and LIM domain 1 -3.15789
NT5DC2 5'-nucleotidase domain containing 2 -2.36922
SESN1 sestrin 1 -2.26148
FSTL3 follistatin-like 3 (secreted glycoprotein) -2.15412
PER1 period circadian clock 1 -2.1022
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.07339