CRCGN015_HEPG2_48H:N05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description naphthalene 33.1 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN015_HEPG2_48H:N05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.43281
TIAM1 T-cell lymphoma invasion and metastasis 1 3.10952
HLA-DRA major histocompatibility complex, class II, DR alpha 2.85699
CD40 CD40 molecule, TNF receptor superfamily member 5 2.65694
CXCL2 chemokine (C-X-C motif) ligand 2 2.47669

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.0571
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.64765
VDAC1 voltage-dependent anion channel 1 -2.58308
AURKB aurora kinase B -2.37272
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.2982
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.13306