CRCGN015_HEPG2_48H:N08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyl nitrite 32.1 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_HEPG2_48H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNX11 sorting nexin 11 4.03197
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 3.95922
PNKP polynucleotide kinase 3'-phosphatase 3.61393
CDK19 cyclin-dependent kinase 19 2.60946
MAP7 microtubule-associated protein 7 2.57754
KPTN kaptin (actin binding protein) 2.47412
FZD7 frizzled class receptor 7 2.44295
CBX1 chromobox homolog 1 2.27193
PTOV1 prostate tumor overexpressed 1 2.25423
KDM5A lysine (K)-specific demethylase 5A 2.19883
WIF1 WNT inhibitory factor 1 2.18511
TFG TRK-fused gene 2.14605
THTPA thiamine triphosphatase 2.14443
FPGS folylpolyglutamate synthase 2.13677
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.12893
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.08968
NTM neurotrimin 2.01163

decreased expression

Symbol Name Standardized Value
TM9SF3 transmembrane 9 superfamily member 3 -5.40775
SLC35F2 solute carrier family 35, member F2 -3.33604
S100P S100 calcium binding protein P -3.15366
MT1X metallothionein 1X -2.95118
HOXA4 homeobox A4 -2.05903
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -2.05194
NOP16 NOP16 nucleolar protein -2.03514