CRCGN015_HEPG2_48H:N09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyl nitrite 10.7 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_HEPG2_48H:N09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 4.16194
CRTAP cartilage associated protein 3.59466
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.72068
RNF130 ring finger protein 130 2.36397
KAT6A K(lysine) acetyltransferase 6A 2.30209

decreased expression

Symbol Name Standardized Value
ENOPH1 enolase-phosphatase 1 -5.30668
LOC124907782 dual specificity protein phosphatase 22 -4.01466
CD58 CD58 molecule -2.98553
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.6082
RHOB ras homolog family member B -2.47195
COPS4 COP9 signalosome subunit 4 -2.4372
IQCB1 IQ motif containing B1 -2.38963
SMAP1 small ArfGAP 1 -2.23418
APOH apolipoprotein H (beta-2-glycoprotein I) -2.21071
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -2.17919
SEC31A SEC31 homolog A (S. cerevisiae) -2.09709
MT1X metallothionein 1X -2.06932