CRCGN015_HEPG2_48H:N11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetranitromethane 33.77 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

9 genes differentially expressed following the CRCGN015_HEPG2_48H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.04
CHMP6 charged multivesicular body protein 6 4.66517
MOK MOK protein kinase 3.53488
COPS7A COP9 signalosome subunit 7A 2.88155
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.01966
SYNE2 spectrin repeat containing, nuclear envelope 2 2.00556

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.75308
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.93115
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 -2.18591