CRCGN015_HEPG2_48H:N12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tetranitromethane 11.26 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN015_HEPG2_48H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.3377
CDPF1 cysteine-rich, DPF motif domain containing 1 4.04905
GATD3 glutamine amidotransferase class 1 domain containing 3 3.15548
MOK MOK protein kinase 2.93689
GPER1 G protein-coupled estrogen receptor 1 2.82949
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.77411
TMEM14A transmembrane protein 14A 2.50294
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.40061
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 2.32301
H2BC21 H2B clustered histone 21 2.29897
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.23557
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.22087
PFKL phosphofructokinase, liver 2.22061
ITFG1 integrin alpha FG-GAP repeat containing 1 2.19287
RWDD2B RWD domain containing 2B 2.1841
PRR11 proline rich 11 2.14592
UBE2A ubiquitin-conjugating enzyme E2A 2.10358
TBXA2R thromboxane A2 receptor 2.07445
HAUS2 HAUS augmin-like complex, subunit 2 2.06786
HSPA12A heat shock 70kDa protein 12A 2.04709
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 2.03682
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.02756
UFM1 ubiquitin-fold modifier 1 2.02234
EPS8L2 EPS8-like 2 2.01521

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.16013
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.70475
VAT1 vesicle amine transport 1 -2.65186
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.60259
PLIN2 perilipin 2 -2.49831
PECR peroxisomal trans-2-enoyl-CoA reductase -2.47935
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -2.47829
RNPS1 RNA binding protein S1, serine-rich domain -2.32797
MED24 mediator complex subunit 24 -2.31991
ZNF274 zinc finger protein 274 -2.31921
GFOD1 glucose-fructose oxidoreductase domain containing 1 -2.21225
GALP galanin-like peptide -2.18777
CASC3 cancer susceptibility candidate 3 -2.15087
DCP1A decapping mRNA 1A -2.11703
RAB4A RAB4A, member RAS oncogene family -2.09426