CRCGN015_HEPG2_48H:N14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cobalt sulfate heptahydrate 33.43 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_HEPG2_48H:N14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 6.33415
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 6.22349
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.53855
KDM3A lysine (K)-specific demethylase 3A 3.84065
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 3.8068
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.37994
INSIG2 insulin induced gene 2 3.05024
ALDOC aldolase C, fructose-bisphosphate 2.95752
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.83301
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 2.75379
CA9 carbonic anhydrase IX 2.28006
HILPDA hypoxia inducible lipid droplet-associated 2.261
KDM5D lysine (K)-specific demethylase 5D 2.24631
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.23037
IPO13 importin 13 2.10229
EGLN3 egl-9 family hypoxia-inducible factor 3 2.01896

decreased expression

Symbol Name Standardized Value
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -5.12677
VAT1 vesicle amine transport 1 -3.42793
CCDC86 coiled-coil domain containing 86 -2.67977
TEX10 testis expressed 10 -2.61941
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.34703
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.31336
RPP25 ribonuclease P/MRP 25kDa subunit -2.11913
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -2.00538
AARSD1 alanyl-tRNA synthetase domain containing 1 -2.00239