CRCGN015_HEPG2_48H:N17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-epoxybutane 32.43 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN015_HEPG2_48H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 4.42719
FPGS folylpolyglutamate synthase 2.60669
SPAG4 sperm associated antigen 4 2.33896
GTPBP8 GTP-binding protein 8 (putative) 2.30341
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.29391
ATXN7 ataxin 7 2.13037
TSPAN6 tetraspanin 6 2.09614
GLCE glucuronic acid epimerase 2.05937

decreased expression

Symbol Name Standardized Value
ENOPH1 enolase-phosphatase 1 -4.67335
CHMP4B charged multivesicular body protein 4B -4.48437
COPS4 COP9 signalosome subunit 4 -2.78247
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog -2.29619
AATF apoptosis antagonizing transcription factor -2.18231