CRCGN015_HEPG2_48H:N19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KIF5C kinesin family member 5C 3.45688
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 3.03224
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.31807
SYK spleen tyrosine kinase 2.12518

decreased expression

Symbol Name Standardized Value
IFRD2 interferon-related developmental regulator 2 -3.39756
TM9SF3 transmembrane 9 superfamily member 3 -3.35737
TXNRD1 thioredoxin reductase 1 -2.53262
PDZD2 PDZ domain containing 2 -2.45932
CCNH cyclin H -2.38744
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.24099
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.21803
CSRP2 cysteine and glycine-rich protein 2 -2.09366
TBC1D31 TBC1 domain family, member 31 -2.07254
MT1X metallothionein 1X -2.03789
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -2.00477