CRCGN015_HEPG2_48H:N24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenylephrine 11.31 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_HEPG2_48H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SCRN1 secernin 1 5.23147
ABHD6 abhydrolase domain containing 6 3.6174
ZNF589 zinc finger protein 589 3.47936
EPHB2 EPH receptor B2 3.47854
ANO10 anoctamin 10 3.15376
MINDY1 MINDY lysine 48 deubiquitinase 1 3.15164
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.3527
CRELD2 cysteine-rich with EGF-like domains 2 2.34312
CUX2 cut-like homeobox 2 2.32499
DNASE1L3 deoxyribonuclease I-like 3 2.31554

decreased expression

Symbol Name Standardized Value
PROM1 prominin 1 -4.81333
MT1X metallothionein 1X -4.48941
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -4.21037
TUBB6 tubulin, beta 6 class V -4.02604
FASTKD5 FAST kinase domains 5 -3.82751
RHOB ras homolog family member B -2.59096
TM9SF3 transmembrane 9 superfamily member 3 -2.56355
LAP3 leucine aminopeptidase 3 -2.54042
S100P S100 calcium binding protein P -2.29429