CRCGN015_HEPG2_48H:O02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_HEPG2_48H:O02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 3.60356
GSTZ1 glutathione S-transferase zeta 1 2.36969
IGFBP3 insulin-like growth factor binding protein 3 2.17056
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.07766

decreased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.24275
S100P S100 calcium binding protein P -4.08551
CDC20 cell division cycle 20 -3.93634
SNX7 sorting nexin 7 -3.89788
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.76957
MAPK13 mitogen-activated protein kinase 13 -3.55111
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.35365
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.35352
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.19647
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.91545
PDLIM1 PDZ and LIM domain 1 -2.60163
DUSP6 dual specificity phosphatase 6 -2.4528
RHOB ras homolog family member B -2.032