| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 48 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
53 genes differentially expressed following the CRCGN015_HEPG2_48H:O03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 4.30362 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 4.2864 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.73928 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.72405 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.5183 |
| VGLL4 | vestigial-like family member 4 | 3.44073 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 3.15426 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 3.1502 |
| CBR3 | carbonyl reductase 3 | 2.88602 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 2.6076 |
| TKTL1 | transketolase-like 1 | 2.53062 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 2.40809 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.38628 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | 2.34763 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.33117 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | 2.24234 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.21204 |
| FPGS | folylpolyglutamate synthase | 2.16022 |
| FLT3 | fms-related tyrosine kinase 3 | 2.13923 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 2.10696 |
| CRH | corticotropin releasing hormone | 2.10549 |
| BAG1 | BCL2-associated athanogene | 2.05722 |
| RWDD2A | RWD domain containing 2A | 2.04904 |
| LPL | lipoprotein lipase | 2.02444 |
| RABL6 | RAB, member RAS oncogene family-like 6 | 2.0159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -6.65584 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -4.85392 |
| RPA3 | replication protein A3, 14kDa | -4.54391 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.50064 |
| CDC20 | cell division cycle 20 | -4.19772 |
| HSPA8 | heat shock 70kDa protein 8 | -4.02523 |
| SLC35F2 | solute carrier family 35, member F2 | -3.90838 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.2314 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.07924 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -2.68015 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -2.67366 |
| ATG4A | autophagy related 4A, cysteine peptidase | -2.62923 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -2.29586 |
| CFHR3 | complement factor H-related 3 | -2.2928 |
| SMYD3 | SET and MYND domain containing 3 | -2.28036 |
| DNM3 | dynamin 3 | -2.22877 |
| KIFAP3 | kinesin-associated protein 3 | -2.18239 |
| FHIT | fragile histidine triad | -2.15932 |
| FEV | FEV (ETS oncogene family) | -2.14539 |
| JAM3 | junctional adhesion molecule 3 | -2.13655 |
| TUBB4A | tubulin, beta 4A class IVa | -2.1312 |
| NUP42 | nucleoporin 42 | -2.09834 |
| WASHC3 | WASH complex subunit 3 | -2.09637 |
| LOC107986346 | mitochondrial import receptor subunit TOM7 homolog | -2.06882 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | -2.05601 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -2.04944 |
| METTL18 | methyltransferase like 18 | -2.03059 |
| RBM41 | RNA binding motif protein 41 | -2.02262 |
