CRCGN015_HEPG2_48H:O05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN015_HEPG2_48H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.28167
SNX11 sorting nexin 11 2.89473
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.19238
TFDP1 transcription factor Dp-1 2.18368
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.11958

decreased expression

Symbol Name Standardized Value
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.30256
MCUR1 mitochondrial calcium uniporter regulator 1 -3.23683
CDC20 cell division cycle 20 -3.13929
STAT1 signal transducer and activator of transcription 1, 91kDa -2.54982
JMJD6 jumonji domain containing 6 -2.53613
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.36521
CCNH cyclin H -2.22043
TRAPPC3 trafficking protein particle complex 3 -2.21728
PDZD2 PDZ domain containing 2 -2.03623