CRCGN015_HEPG2_48H:O13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description catechol 98.9 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN015_HEPG2_48H:O13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HYOU1 hypoxia up-regulated 1 4.67978
STAP2 signal transducing adaptor family member 2 4.47244
UBE2A ubiquitin-conjugating enzyme E2A 4.09216
IGHMBP2 immunoglobulin mu binding protein 2 3.13596
NMT1 N-myristoyltransferase 1 2.63511
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.51351
CDK2 cyclin-dependent kinase 2 2.39649
KRT75 keratin 75, type II 2.38396
MUC7 mucin 7, secreted 2.24622
REXO2 RNA exonuclease 2 2.22162
CYBRD1 cytochrome b reductase 1 2.1939
NRTN neurturin 2.17772
PRB4 proline-rich protein BstNI subfamily 4 2.16988
CEP192 centrosomal protein 192kDa 2.14597
ZMYM1 zinc finger, MYM-type 1 2.11519
CYTL1 cytokine-like 1 2.11227
KLHL11 kelch-like family member 11 2.10998
CHAD chondroadherin 2.10463
WEE1 WEE1 G2 checkpoint kinase 2.09847
SPRR1B small proline-rich protein 1B 2.06699
XPO4 exportin 4 2.06603
LOC128966570 alpha-amylase 1B 2.05971
AGBL2 ATP/GTP binding protein-like 2 2.05254
WIF1 WNT inhibitory factor 1 2.02746
SOX17 SRY (sex determining region Y)-box 17 2.01571
RIPPLY3 ripply transcriptional repressor 3 2.0135

decreased expression

Symbol Name Standardized Value
PECR peroxisomal trans-2-enoyl-CoA reductase -4.70535
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.38877
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.71742
GGPS1 geranylgeranyl diphosphate synthase 1 -3.54117
APOA2 apolipoprotein A-II -3.26869
TM9SF3 transmembrane 9 superfamily member 3 -2.87104
DCAF10 DDB1 and CUL4 associated factor 10 -2.37995
GNPAT glyceronephosphate O-acyltransferase -2.2503
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.19827
GPSM3 G-protein signaling modulator 3 -2.15118
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.1395
MT1X metallothionein 1X -2.10638
SREK1IP1 SREK1-interacting protein 1 -2.09995
RBM34 RNA binding motif protein 34 -2.09765
TBCE tubulin folding cofactor E -2.08252
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.06853
RNF10 ring finger protein 10 -2.04066