CRCGN015_HEPG2_48H:O14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description catechol 32.97 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_HEPG2_48H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.56429
EVL Enah/Vasp-like 3.9509
CRTAP cartilage associated protein 2.93583
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.87567
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.84855
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.63062
KIFBP kinesin family binding protein 2.56106
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.23048
ODR4 odr-4 GPCR localization factor homolog 2.09271

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.73792
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.51102
LOC124907782 dual specificity protein phosphatase 22 -3.65399
BIRC2 baculoviral IAP repeat containing 2 -2.89519
TP53BP1 tumor protein p53 binding protein 1 -2.67697
RHOB ras homolog family member B -2.54052
MTERF3 mitochondrial transcription termination factor 3 -2.28826
PDZD2 PDZ domain containing 2 -2.11614
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -2.02703