CRCGN015_HEPG2_48H:O18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-nitroacenaphthene 10.93 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

10 genes differentially expressed following the CRCGN015_HEPG2_48H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.94989
CHMP6 charged multivesicular body protein 6 3.55261
PRKCQ protein kinase C, theta 2.83083
PRR7 proline rich 7 (synaptic) 2.35925
IGHMBP2 immunoglobulin mu binding protein 2 2.27141
FPGS folylpolyglutamate synthase 2.10638

decreased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P -3.56089
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.79739
GNAS GNAS complex locus -2.6041
CCNH cyclin H -2.01015