CRCGN015_HEPG2_48H:O23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 35.0 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_HEPG2_48H:O23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COQ8A coenzyme Q8A 5.039
STAP2 signal transducing adaptor family member 2 4.19604
HDGFL3 HDGF like 3 3.63114
CCNF cyclin F 2.86321
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.64338
SIRT3 sirtuin 3 2.63434
KLHL21 kelch-like family member 21 2.5039
TRAK2 trafficking protein, kinesin binding 2 2.42255
NPM3 nucleophosmin/nucleoplasmin 3 2.31928
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.23144
ZBTB5 zinc finger and BTB domain containing 5 2.09358
XK X-linked Kx blood group 2.05442

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.36253
CXADR coxsackie virus and adenovirus receptor -4.25636
FBXL12 F-box and leucine-rich repeat protein 12 -3.98824
HEATR1 HEAT repeat containing 1 -3.47706
PECR peroxisomal trans-2-enoyl-CoA reductase -3.39877
S100P S100 calcium binding protein P -3.10755
APOH apolipoprotein H (beta-2-glycoprotein I) -2.93006
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.81896
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.46001
DND1 DND microRNA-mediated repression inhibitor 1 -2.44291
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -2.23162
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -2.1934
UPK3B uroplakin 3B -2.14882
HAVCR1 hepatitis A virus cellular receptor 1 -2.14656
CRYGD crystallin, gamma D -2.08494
TM9SF2 transmembrane 9 superfamily member 2 -2.07186
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.05524
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -2.05019
SPRING1 SREBF pathway regulator in golgi 1 -2.04396
HEBP1 heme binding protein 1 -2.01377