CRCGN015_HEPG2_48H:P01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acedapsone 98.29 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_HEPG2_48H:P01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.17809
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.68529
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.58548
MAP7 microtubule-associated protein 7 2.4917
ANO10 anoctamin 10 2.30052
CDC25B cell division cycle 25B 2.0843
GADD45B growth arrest and DNA-damage-inducible, beta 2.0608

decreased expression

Symbol Name Standardized Value
PROM1 prominin 1 -3.51605
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.0379
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.9648
CXADR coxsackie virus and adenovirus receptor -2.80683
WASHC4 WASH complex subunit 4 -2.78091
TSPAN4 tetraspanin 4 -2.40714
RANBP17 RAN binding protein 17 -2.36505
CD93 CD93 molecule -2.26229
KIF20A kinesin family member 20A -2.18677
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.08185
MATN1 matrilin 1, cartilage matrix protein -2.04042
ADGRA2 adhesion G protein-coupled receptor A2 -2.03339
MT1X metallothionein 1X -2.01486
NANOS2 nanos homolog 2 (Drosophila) -2.01232