| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-aminodiphenyl 100.07 um perturbation at 48 h in HEPG2 (Carcinogenome) |
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55 genes differentially expressed following the CRCGN015_HEPG2_48H:P07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUCB2 | nucleobindin 2 | 4.50028 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 3.76223 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 3.55522 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | 3.30797 |
| ANO10 | anoctamin 10 | 3.23249 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 3.07659 |
| PRKCH | protein kinase C, eta | 3.05984 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.88864 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.72718 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 | 2.45318 |
| CPA4 | carboxypeptidase A4 | 2.42235 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.37621 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 2.25298 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 2.22268 |
| CHPF | chondroitin polymerizing factor | 2.21956 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.193 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 2.19211 |
| NAGA | N-acetylgalactosaminidase, alpha- | 2.1888 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 2.18857 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 2.14325 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.07949 |
| TMEM14A | transmembrane protein 14A | 2.07105 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 2.05823 |
| CORO1A | coronin, actin binding protein, 1A | 2.05018 |
| DPP4 | dipeptidyl-peptidase 4 | 2.04891 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | 2.0248 |
| EDNRB | endothelin receptor type B | 2.00161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IER3 | immediate early response 3 | -3.92589 |
| ISOC1 | isochorismatase domain containing 1 | -3.21758 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.96177 |
| CXADR | coxsackie virus and adenovirus receptor | -2.76663 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.75819 |
| NSUN3 | NOP2/Sun domain family, member 3 | -2.7299 |
| TRIB1 | tribbles pseudokinase 1 | -2.6622 |
| MT1X | metallothionein 1X | -2.58917 |
| S100P | S100 calcium binding protein P | -2.58578 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -2.52678 |
| HMGA2 | high mobility group AT-hook 2 | -2.48545 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -2.46816 |
| LOC122526780 | uncharacterized LOC122526780 | -2.43828 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.42812 |
| KIFBP | kinesin family binding protein | -2.42227 |
| FAIM | Fas apoptotic inhibitory molecule | -2.34985 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.30134 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -2.22965 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -2.20867 |
| TBPL1 | TBP-like 1 | -2.18449 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -2.18082 |
| PCNP | PEST proteolytic signal containing nuclear protein | -2.14388 |
| H2AZ2 | H2A.Z variant histone 2 | -2.11447 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -2.11348 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -2.0555 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.04499 |
| ZNF263 | zinc finger protein 263 | -2.01997 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -2.01406 |