CRCGN015_HEPG2_48H:P11 Gene Set
Genes
32 genes differentially expressed following the CRCGN015_HEPG2_48H:P11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABHD6
|
abhydrolase domain containing 6
|
3.98684
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.90467
|
|
DFFA
|
DNA fragmentation factor, 45kDa, alpha polypeptide
|
3.4811
|
|
CCNA1
|
cyclin A1
|
2.6279
|
|
PPOX
|
protoporphyrinogen oxidase
|
2.61552
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.45849
|
|
MAP2K5
|
mitogen-activated protein kinase kinase 5
|
2.40914
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
2.38793
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.19155
|
|
SCRN1
|
secernin 1
|
2.1727
|
|
ASNS
|
asparagine synthetase (glutamine-hydrolyzing)
|
2.07352
|
|
DSG2
|
desmoglein 2
|
2.04212
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLIN2
|
perilipin 2
|
-4.5142
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.7401
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.57842
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.50049
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.44687
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.2778
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.54874
|
|
RHOB
|
ras homolog family member B
|
-2.47956
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.2637
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.23996
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-2.19479
|
|
DMAC2L
|
distal membrane arm assembly component 2 like
|
-2.179
|
|
UBL5
|
ubiquitin-like 5
|
-2.16173
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.1595
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.15898
|
|
IER3
|
immediate early response 3
|
-2.14984
|
|
TM7SF2
|
transmembrane 7 superfamily member 2
|
-2.08846
|
|
MZT2B
|
mitotic spindle organizing protein 2B
|
-2.08843
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.08439
|
|
P2RY2
|
purinergic receptor P2Y, G-protein coupled, 2
|
-2.0695
|
