CRCGN015_HEPG2_48H:P12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description megestrol 11.07 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_HEPG2_48H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.59628
CIAO3 cytosolic iron-sulfur assembly component 3 3.25455
CXCR4 chemokine (C-X-C motif) receptor 4 2.78897
MICALL1 MICAL-like 1 2.45741
SLC66A2 solute carrier family 66 member 2 2.07619
KRT16 keratin 16, type I 2.05142

decreased expression

Symbol Name Standardized Value
PLIN2 perilipin 2 -5.41972
TM9SF3 transmembrane 9 superfamily member 3 -4.2604
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -3.44735
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.1405
IER3 immediate early response 3 -2.26868
RBM34 RNA binding motif protein 34 -2.22193
TAOK3 TAO kinase 3 -2.15755
TCF21 transcription factor 21 -2.12116
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.02857