CRCGN015_HEPG2_48H:P16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description amsonic acid 100.55 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_HEPG2_48H:P16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 4.49565
CXCR4 chemokine (C-X-C motif) receptor 4 4.25638
COQ8A coenzyme Q8A 3.87625
PLSCR3 phospholipid scramblase 3 3.72
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.31749
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 2.15323
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.13248
CCDC170 coiled-coil domain containing 170 2.11176

decreased expression

Symbol Name Standardized Value
RHOB ras homolog family member B -5.88257
TRIB3 tribbles pseudokinase 3 -4.71709
BIRC2 baculoviral IAP repeat containing 2 -4.69211
PDLIM1 PDZ and LIM domain 1 -4.15922
CHIC2 cysteine-rich hydrophobic domain 2 -2.89918
RXYLT1 ribitol xylosyltransferase 1 -2.4082
S100P S100 calcium binding protein P -2.18282
NGLY1 N-glycanase 1 -2.15223
KIFC3 kinesin family member C3 -2.13886
APOH apolipoprotein H (beta-2-glycoprotein I) -2.09831
MPIG6B megakaryocyte and platelet inhibitory receptor G6b -2.01908
CDC25B cell division cycle 25B -2.0026