CRCGN015_HEPG2_48H:P18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description amsonic acid 11.17 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_HEPG2_48H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.11902
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.45044
GSTM2 glutathione S-transferase mu 2 (muscle) 2.32751
IFT81 intraflagellar transport 81 2.16747
EAPP E2F-associated phosphoprotein 2.05628
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.03171

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -4.83104
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.79349
BIRC2 baculoviral IAP repeat containing 2 -4.10854
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -4.07026
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.49586
RBM34 RNA binding motif protein 34 -3.12961
CXADR coxsackie virus and adenovirus receptor -2.665
TM9SF3 transmembrane 9 superfamily member 3 -2.40113
GGPS1 geranylgeranyl diphosphate synthase 1 -2.3158
ZC3H3 zinc finger CCCH-type containing 3 -2.29505
MT1X metallothionein 1X -2.29359
SHARPIN SHANK-associated RH domain interactor -2.20824
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) -2.1795
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.10529
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.08706
CAPN5 calpain 5 -2.0742
ZNF16 zinc finger protein 16 -2.05891
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.00395