CRCGN015_HEPG2_48H:P21 Gene Set
Genes
39 genes differentially expressed following the CRCGN015_HEPG2_48H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HYOU1
|
hypoxia up-regulated 1
|
4.86416
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
3.46543
|
|
UBE4A
|
ubiquitination factor E4A
|
2.96087
|
|
CYB561
|
cytochrome b561
|
2.70668
|
|
EXOSC4
|
exosome component 4
|
2.57561
|
|
NOL8
|
nucleolar protein 8
|
2.54519
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.4304
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
2.40927
|
|
CHPF
|
chondroitin polymerizing factor
|
2.28072
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.23303
|
|
ZMPSTE24
|
zinc metallopeptidase STE24
|
2.23262
|
|
TEX10
|
testis expressed 10
|
2.20204
|
|
NFRKB
|
nuclear factor related to kappaB binding protein
|
2.17972
|
|
TBC1D10C
|
TBC1 domain family, member 10C
|
2.17837
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.14225
|
|
ICE1
|
interactor of little elongation complex ELL subunit 1
|
2.12879
|
|
CBLIF
|
cobalamin binding intrinsic factor
|
2.07172
|
|
PLD2
|
phospholipase D2
|
2.06747
|
|
EI24
|
etoposide induced 2.4
|
2.05955
|
|
COPS7B
|
COP9 signalosome subunit 7B
|
2.03764
|
|
FPGS
|
folylpolyglutamate synthase
|
2.00559
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PDLIM1
|
PDZ and LIM domain 1
|
-3.69153
|
|
DMAC2L
|
distal membrane arm assembly component 2 like
|
-3.1548
|
|
LYPLA1
|
lysophospholipase I
|
-2.97845
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
-2.95974
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.90119
|
|
SNX6
|
sorting nexin 6
|
-2.59604
|
|
MRPL15
|
mitochondrial ribosomal protein L15
|
-2.38515
|
|
PEX26
|
peroxisomal biogenesis factor 26
|
-2.25258
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-2.16987
|
|
CPNE3
|
copine III
|
-2.13502
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.11871
|
|
GNB1
|
guanine nucleotide binding protein (G protein), beta polypeptide 1
|
-2.10321
|
|
CXADR
|
coxsackie virus and adenovirus receptor
|
-2.09849
|
|
CCDC6
|
coiled-coil domain containing 6
|
-2.05304
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
-2.04938
|
|
PLXDC2
|
plexin domain containing 2
|
-2.03497
|
|
ZNF652
|
zinc finger protein 652
|
-2.02244
|
|
RANGRF
|
RAN guanine nucleotide release factor
|
-2.0056
|
