CRCGN015_HEPG2_48H:P23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibenzo[a,h]pyrene 33.49 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

1403 genes differentially expressed following the CRCGN015_HEPG2_48H:P23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 8.39416
INPP1 inositol polyphosphate-1-phosphatase 6.30146
CEMIP2 cell migration inducing hyaluronidase 2 6.00619
ABHD4 abhydrolase domain containing 4 5.96072
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.7998
FHL2 four and a half LIM domains 2 5.72507
DDB2 damage-specific DNA binding protein 2, 48kDa 5.3932
PHLDA3 pleckstrin homology-like domain, family A, member 3 5.3338
CYTH1 cytohesin 1 5.32832
RALB v-ral simian leukemia viral oncogene homolog B 5.24987
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 5.19285
MAPK13 mitogen-activated protein kinase 13 5.02295
IL4R interleukin 4 receptor 4.86112
XPC xeroderma pigmentosum, complementation group C 4.82854
TRIB1 tribbles pseudokinase 1 4.80055
MICALL1 MICAL-like 1 4.7971
FDXR ferredoxin reductase 4.78147
TP53I3 tumor protein p53 inducible protein 3 4.75216
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.73569
FOSL1 FOS-like antigen 1 4.72135
RRAGC Ras-related GTP binding C 4.67509
FSTL3 follistatin-like 3 (secreted glycoprotein) 4.63739
REXO2 RNA exonuclease 2 4.47328
IER3 immediate early response 3 4.46454
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 4.43357
TIGAR TP53 induced glycolysis regulatory phosphatase 4.42632
H2BC21 H2B clustered histone 21 4.39775
DUSP6 dual specificity phosphatase 6 4.32613
INO80B INO80 complex subunit B 4.29122
PARP3 poly (ADP-ribose) polymerase family, member 3 4.27826
SCRN1 secernin 1 4.24745
BTG2 BTG family, member 2 4.24325
EPHA2 EPH receptor A2 4.21967
BLCAP bladder cancer associated protein 4.20354
LRP10 low density lipoprotein receptor-related protein 10 4.17661
AEN apoptosis enhancing nuclease 4.06864
CCDC86 coiled-coil domain containing 86 4.06217
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 4.05861
LOC122526780 uncharacterized LOC122526780 4.05539
ZMAT3 zinc finger, matrin-type 3 4.04348
ZNF79 zinc finger protein 79 4.01176
TUT7 terminal uridylyl transferase 7 3.98949
EPS8L2 EPS8-like 2 3.97771
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 3.95888
PLK3 polo-like kinase 3 3.93967
MYH9 myosin, heavy chain 9, non-muscle 3.93567
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.93324
LOC102724023 ES1 protein homolog, mitochondrial 3.92224
FASN fatty acid synthase 3.91951
TBK1 TANK-binding kinase 1 3.90744
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 3.9065
MVP major vault protein 3.89825
VAT1 vesicle amine transport 1 3.86888
ATOSB atos homolog B 3.8573
SQSTM1 sequestosome 1 3.84253
OSGIN1 oxidative stress induced growth inhibitor 1 3.82038
GMIP GEM interacting protein 3.76127
GABARAPL1 GABA(A) receptor-associated protein like 1 3.75058
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.74866
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 3.73622
PNPLA6 patatin-like phospholipase domain containing 6 3.73277
RNF103 ring finger protein 103 3.72147
SKIC2 SKI2 subunit of superkiller complex 3.71511
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.70209
TERF2IP telomeric repeat binding factor 2, interacting protein 3.6994
FURIN furin (paired basic amino acid cleaving enzyme) 3.69756
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 3.68279
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.681
MAPKBP1 mitogen-activated protein kinase binding protein 1 3.67489
RAP1GAP RAP1 GTPase activating protein 3.65006
FPGS folylpolyglutamate synthase 3.64452
SMAD3 SMAD family member 3 3.64272
GPC1 glypican 1 3.64149
CDIP1 cell death-inducing p53 target 1 3.59092
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.56266
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.55157
GIPC1 GIPC PDZ domain containing family, member 1 3.53857
CCDC90B coiled-coil domain containing 90B 3.53174
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 3.52696
PINK1 PTEN induced putative kinase 1 3.52353
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.51369
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 3.50734
GSDME gasdermin E 3.49228
CALCOCO1 calcium binding and coiled-coil domain 1 3.48453
ITPKC inositol-trisphosphate 3-kinase C 3.45932
PRKCD protein kinase C, delta 3.43263
ITGAV integrin, alpha V 3.4316
CHIC2 cysteine-rich hydrophobic domain 2 3.42793
SOX4 SRY (sex determining region Y)-box 4 3.41916
CHPF2 chondroitin polymerizing factor 2 3.41385
BATF basic leucine zipper transcription factor, ATF-like 3.41304
SYNRG synergin, gamma 3.41082
BECN1 beclin 1, autophagy related 3.40263
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.39412
ZFAND5 zinc finger, AN1-type domain 5 3.38336
TIMP2 TIMP metallopeptidase inhibitor 2 3.38049
CDA cytidine deaminase 3.37156
STOM stomatin 3.36837
S100A3 S100 calcium binding protein A3 3.36834
AOX1 aldehyde oxidase 1 3.34912
ELL2 elongation factor, RNA polymerase II, 2 3.3354
ATG2A autophagy related 2A 3.33125
CES2 carboxylesterase 2 3.32566
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 3.32012
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.31991
CXCR4 chemokine (C-X-C motif) receptor 4 3.31835
DUSP14 dual specificity phosphatase 14 3.3
ZNF358 zinc finger protein 358 3.2983
RABL6 RAB, member RAS oncogene family-like 6 3.29406
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.28307
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.28234
SMIM40 small integral membrane protein 40 3.27458
HSPA4L heat shock 70kDa protein 4-like 3.26867
TXNRD1 thioredoxin reductase 1 3.26116
SOCS2 suppressor of cytokine signaling 2 3.25829
SQOR sulfide quinone oxidoreductase 3.25444
TRIP10 thyroid hormone receptor interactor 10 3.25274
YPEL5 yippee-like 5 (Drosophila) 3.24756
POLL polymerase (DNA directed), lambda 3.24408
CDK9 cyclin-dependent kinase 9 3.24086
SDC4 syndecan 4 3.23247
BAAT bile acid CoA:amino acid N-acyltransferase 3.21712
KCMF1 potassium channel modulatory factor 1 3.21022
PHF1 PHD finger protein 1 3.19515
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3.19511
LYPLA2 lysophospholipase II 3.19321
HEBP1 heme binding protein 1 3.19278
DOK4 docking protein 4 3.18939
WDR46 WD repeat domain 46 3.17803
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 3.1738
RPS27L ribosomal protein S27-like 3.17285
LIF leukemia inhibitory factor 3.16345
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 3.15894
LAMB3 laminin, beta 3 3.15056
MCOLN1 mucolipin 1 3.14529
ASCC3 activating signal cointegrator 1 complex subunit 3 3.1253
PFN2 profilin 2 3.12341
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 3.12335
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 3.12134
GCC2 GRIP and coiled-coil domain containing 2 3.11787
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.11718
CAPRIN2 caprin family member 2 3.10898
INPPL1 inositol polyphosphate phosphatase-like 1 3.10714
ACADVL acyl-CoA dehydrogenase, very long chain 3.10509
EXOC2 exocyst complex component 2 3.09827
ZNF276 zinc finger protein 276 3.09593
DOK7 docking protein 7 3.0936
CCDC92 coiled-coil domain containing 92 3.08601
H2AC6 H2A clustered histone 6 3.08342
RNF25 ring finger protein 25 3.08122
RIOK3 RIO kinase 3 3.07789
ABI1 abl-interactor 1 3.06235
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 3.05656
COL17A1 collagen, type XVII, alpha 1 3.05483
TRIP12 thyroid hormone receptor interactor 12 3.04758
FAT1 FAT atypical cadherin 1 3.03503
MAP7D1 MAP7 domain containing 1 3.01829
GDI1 GDP dissociation inhibitor 1 3.01663
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 3.01585
TFE3 transcription factor binding to IGHM enhancer 3 3.0155
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 3.01486
PXDC1 PX domain containing 1 3.01436
KDM3A lysine (K)-specific demethylase 3A 3.00923
AMPD2 adenosine monophosphate deaminase 2 3.00609
WASHC3 WASH complex subunit 3 3.00392
EGR1 early growth response 1 2.99809
KDM5C lysine (K)-specific demethylase 5C 2.99407
SPATA20 spermatogenesis associated 20 2.9884
STK17A serine/threonine kinase 17a 2.98787
FAM50A family with sequence similarity 50, member A 2.97501
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.97262
WDR13 WD repeat domain 13 2.96989
FBRS fibrosin 2.96418
TXLNA taxilin alpha 2.9613
PERP PERP, TP53 apoptosis effector 2.96101
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 2.95748
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 2.95681
ACOT9 acyl-CoA thioesterase 9 2.95492
BCAR3 breast cancer anti-estrogen resistance 3 2.95409
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.95393
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.95281
TCF15 transcription factor 15 (basic helix-loop-helix) 2.95222
CCSER2 coiled-coil serine-rich protein 2 2.95159
PDLIM7 PDZ and LIM domain 7 (enigma) 2.94994
TRAPPC14 trafficking protein particle complex subunit 14 2.94872
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.94785
HABP4 hyaluronan binding protein 4 2.94495
RING1 ring finger protein 1 2.94494
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.93431
DAPK3 death-associated protein kinase 3 2.91539
MACF1 microtubule-actin crosslinking factor 1 2.91227
CHMP1B charged multivesicular body protein 1B 2.90414
ULK1 unc-51 like autophagy activating kinase 1 2.90339
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.90305
STAMBP STAM binding protein 2.88174
PLEC plectin 2.88111
NAV2 neuron navigator 2 2.87608
KDM6B lysine (K)-specific demethylase 6B 2.86548
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.86319
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.86084
ZBTB17 zinc finger and BTB domain containing 17 2.85991
MEAF6 MYST/Esa1-associated factor 6 2.84998
GOLGB1 golgin B1 2.84733
TOMM34 translocase of outer mitochondrial membrane 34 2.84018
TP53TG5 TP53 target 5 2.83439
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.83131
ACBD4 acyl-CoA binding domain containing 4 2.82792
IL32 interleukin 32 2.82659
YIPF3 Yip1 domain family, member 3 2.82331
LOC124904942 uncharacterized LOC124904942 2.81328
PLSCR3 phospholipid scramblase 3 2.8099
CTF1 cardiotrophin 1 2.80691
SYNGR3 synaptogyrin 3 2.80464
CST4 cystatin S 2.80062
NECAP2 NECAP endocytosis associated 2 2.79794
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.79749
MAP2K3 mitogen-activated protein kinase kinase 3 2.79541
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.79414
CDC34 cell division cycle 34 2.79125
METTL22 methyltransferase like 22 2.78661
ADGRG1 adhesion G protein-coupled receptor G1 2.78439
KCTD17 potassium channel tetramerization domain containing 17 2.77394
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.75838
VPREB1 pre-B lymphocyte 1 2.757
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.75455
IGF2R insulin-like growth factor 2 receptor 2.74041
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.73992
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.73869
HOXA3 homeobox A3 2.73134
BCL2L1 BCL2-like 1 2.7291
STXBP2 syntaxin binding protein 2 2.72226
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.71984
ATG4A autophagy related 4A, cysteine peptidase 2.71636
FXR2 fragile X mental retardation, autosomal homolog 2 2.71628
COL7A1 collagen, type VII, alpha 1 2.71401
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.70641
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.70553
KRT17 keratin 17, type I 2.70351
ZSWIM8 zinc finger, SWIM-type containing 8 2.70332
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 2.70163
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.69639
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.69484
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 2.69089
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.68729
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.68488
FAM174C family with sequence similarity 174 member C 2.68276
MCL1 myeloid cell leukemia 1 2.67913
RALGDS ral guanine nucleotide dissociation stimulator 2.67772
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.67447
PLEK2 pleckstrin 2 2.6741
EDN2 endothelin 2 2.67212
DDA1 DET1 and DDB1 associated 1 2.66911
TUBG2 tubulin, gamma 2 2.6654
WBP1L WW domain binding protein 1-like 2.66402
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.66039
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 2.65973
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.65247
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.64876
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.64437
FOSL2 FOS-like antigen 2 2.64326
BCORL1 BCL6 corepressor-like 1 2.64163
LOC127933115 uncharacterized LOC127933115 2.63764
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.63383
KIFC3 kinesin family member C3 2.63247
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 2.63032
LOC102724428 serine/threonine-protein kinase SIK1 2.6283
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.62389
KIF3C kinesin family member 3C 2.62232
CARD10 caspase recruitment domain family, member 10 2.6189
BORCS8 BLOC-1 related complex subunit 8 2.60704
BHLHE40 basic helix-loop-helix family, member e40 2.60685
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 2.60161
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.60116
ARSD arylsulfatase D 2.59713
HSPB1 heat shock 27kDa protein 1 2.59641
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.59505
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.58942
PNRC2 proline-rich nuclear receptor coactivator 2 2.58901
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.58773
CTTN cortactin 2.58764
GNL1 guanine nucleotide binding protein-like 1 2.58326
PPME1 protein phosphatase methylesterase 1 2.58217
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.58133
IP6K2 inositol hexakisphosphate kinase 2 2.5805
MBD1 methyl-CpG binding domain protein 1 2.57926
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.57771
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.5724
WHRN whirlin 2.57198
ZBTB38 zinc finger and BTB domain containing 38 2.56294
LPIN1 lipin 1 2.56048
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2.55791
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.55157
CCDC93 coiled-coil domain containing 93 2.54978
ERCC5 excision repair cross-complementation group 5 2.54874
SURF2 surfeit 2 2.54818
TBX3 T-box 3 2.54131
NELFE negative elongation factor complex member E 2.54063
IQCB1 IQ motif containing B1 2.53889
MIDEAS mitotic deacetylase associated SANT domain protein 2.53851
NOP2 NOP2 nucleolar protein 2.53675
SLC75A1 solute carrier family 75 member 1 2.53626
TNPO1 transportin 1 2.53334
RAB7A RAB7A, member RAS oncogene family 2.53155
PARP12 poly (ADP-ribose) polymerase family, member 12 2.52665
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.52303
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.51902
DCTN1 dynactin 1 2.51847
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.51699
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.51691
BBC3 BCL2 binding component 3 2.51633
RABAC1 Rab acceptor 1 (prenylated) 2.5115
TWF2 twinfilin actin binding protein 2 2.51139
RHOC ras homolog family member C 2.51111
WDR26 WD repeat domain 26 2.50952
THSD1 thrombospondin, type I, domain containing 1 2.50583
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.50497
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.50071
ZMPSTE24 zinc metallopeptidase STE24 2.49863
ANGPTL4 angiopoietin-like 4 2.49497
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.48918
AVPI1 arginine vasopressin-induced 1 2.48644
UBAP1 ubiquitin associated protein 1 2.48585
SLC38A7 solute carrier family 38, member 7 2.48514
ARID4B AT rich interactive domain 4B (RBP1-like) 2.47924
HTRA2 HtrA serine peptidase 2 2.47794
ARSA arylsulfatase A 2.4765
BSDC1 BSD domain containing 1 2.4765
MFSD1 major facilitator superfamily domain containing 1 2.47436
PDCD6IP programmed cell death 6 interacting protein 2.47358
APOL2 apolipoprotein L, 2 2.47358
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.47338
DUSP3 dual specificity phosphatase 3 2.47254
ZBTB20 zinc finger and BTB domain containing 20 2.47048
NPPA natriuretic peptide A 2.46807
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.468
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.46465
SLC35F6 solute carrier family 35, member F6 2.46333
EVX1 even-skipped homeobox 1 2.46224
CAPN10 calpain 10 2.45827
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.45796
PHC2 polyhomeotic homolog 2 (Drosophila) 2.45745
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.45495
CLCN7 chloride channel, voltage-sensitive 7 2.44999
NINL ninein-like 2.44951
EGFR epidermal growth factor receptor 2.4493
TRAFD1 TRAF-type zinc finger domain containing 1 2.44774
CAVIN1 caveolae associated protein 1 2.44619
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.44306
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.44112
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.43622
GHITM growth hormone inducible transmembrane protein 2.43598
ZBTB43 zinc finger and BTB domain containing 43 2.43417
GTPBP2 GTP binding protein 2 2.43412
GBA1 glucosylceramidase beta 1 2.43342
KDM4B lysine (K)-specific demethylase 4B 2.43246
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.43166
RUBCN rubicon autophagy regulator 2.42859
PTGES prostaglandin E synthase 2.42713
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.42528
GRB10 growth factor receptor-bound protein 10 2.42496
H2AC19 H2A clustered histone 19 2.42409
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.42223
ORAI3 ORAI calcium release-activated calcium modulator 3 2.42202
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.41678
HDAC7 histone deacetylase 7 2.41455
TRAK1 trafficking protein, kinesin binding 1 2.41211
LMNA lamin A/C 2.41159
CGB8 chorionic gonadotropin, beta polypeptide 8 2.41127
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.40885
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.40861
UBE2H ubiquitin-conjugating enzyme E2H 2.40602
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.40508
FBN2 fibrillin 2 2.40499
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.40379
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.39916
HHAT hedgehog acyltransferase 2.39474
FLRT2 fibronectin leucine rich transmembrane protein 2 2.39328
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.3928
PRDM4 PR domain containing 4 2.39115
ZNF446 zinc finger protein 446 2.39099
CLTB clathrin, light chain B 2.38937
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.38841
TLE6 transducin-like enhancer of split 6 2.38774
CLBA1 clathrin binding box of aftiphilin containing 1 2.38622
TRIM38 tripartite motif containing 38 2.38576
ETFB electron-transfer-flavoprotein, beta polypeptide 2.38409
CD8A CD8a molecule 2.38251
JUN jun proto-oncogene 2.38032
CST2 cystatin SA 2.37853
RYBP RING1 and YY1 binding protein 2.37724
TSC22D4 TSC22 domain family, member 4 2.37406
TRABD TraB domain containing 2.37121
NADSYN1 NAD synthetase 1 2.3684
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.36732
PPL periplakin 2.36381
CIC capicua transcriptional repressor 2.36251
NECTIN2 nectin cell adhesion molecule 2 2.36082
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.35848
UBTD1 ubiquitin domain containing 1 2.35765
HCFC2 host cell factor C2 2.35742
RHOF ras homolog family member F (in filopodia) 2.35364
MSL1 male-specific lethal 1 homolog (Drosophila) 2.34953
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.34838
WIPF2 WAS/WASL interacting protein family, member 2 2.34805
ADA adenosine deaminase 2.3464
ROM1 retinal outer segment membrane protein 1 2.34553
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.34392
EDA2R ectodysplasin A2 receptor 2.34328
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.34278
PORCN porcupine homolog (Drosophila) 2.3427
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.33964
IRX4 iroquois homeobox 4 2.33748
HSF2BP heat shock transcription factor 2 binding protein 2.33689
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.33511
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.32972
USP15 ubiquitin specific peptidase 15 2.3241
PLXNB2 plexin B2 2.32368
NKX6-1 NK6 homeobox 1 2.31905
HMOX2 heme oxygenase 2 2.31728
PSD4 pleckstrin and Sec7 domain containing 4 2.31199
GLRX glutaredoxin (thioltransferase) 2.31192
GPR87 G protein-coupled receptor 87 2.30955
CAVIN2 caveolae associated protein 2 2.30886
CLIP2 CAP-GLY domain containing linker protein 2 2.3074
OSBPL2 oxysterol binding protein-like 2 2.3068
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.30539
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 2.30356
FABP4 fatty acid binding protein 4, adipocyte 2.30204
ADGRE5 adhesion G protein-coupled receptor E5 2.30139
DRAM1 DNA-damage regulated autophagy modulator 1 2.30139
SUGCT succinyl-CoA:glutarate-CoA transferase 2.29969
CTSF cathepsin F 2.29842
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.29829
YJU2B YJU2 splicing factor homolog B 2.2979
GABARAP GABA(A) receptor-associated protein 2.2977
TMEM127 transmembrane protein 127 2.2955
ADAM17 ADAM metallopeptidase domain 17 2.29528
IL2RA interleukin 2 receptor, alpha 2.29456
SETBP1 SET binding protein 1 2.29401
DSG2 desmoglein 2 2.29334
TBC1D3G TBC1 domain family member 3G 2.29189
PGPEP1 pyroglutamyl-peptidase I 2.29095
EIF4A2 eukaryotic translation initiation factor 4A2 2.28965
NCF2 neutrophil cytosolic factor 2 2.28921
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.28895
EXD3 exonuclease 3'-5' domain containing 3 2.28891
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.28876
NEK9 NIMA-related kinase 9 2.28823
CASC3 cancer susceptibility candidate 3 2.28816
ZBTB22 zinc finger and BTB domain containing 22 2.28679
ANKLE2 ankyrin repeat and LEM domain containing 2 2.28421
CLEC16A C-type lectin domain family 16, member A 2.28326
CLDN4 claudin 4 2.28283
KCTD9 potassium channel tetramerization domain containing 9 2.28261
ANXA4 annexin A4 2.28237
ELF4 E74-like factor 4 (ets domain transcription factor) 2.28057
DENND3 DENN/MADD domain containing 3 2.27936
NOTCH1 notch 1 2.27833
ZNF219 zinc finger protein 219 2.27605
OPTN optineurin 2.27597
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.27514
MN1 meningioma (disrupted in balanced translocation) 1 2.27477
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.27255
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.27063
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.2671
BIRC7 baculoviral IAP repeat containing 7 2.26463
BLVRA biliverdin reductase A 2.26431
WDR44 WD repeat domain 44 2.26408
KPNA4 karyopherin alpha 4 (importin alpha 3) 2.26278
SCPEP1 serine carboxypeptidase 1 2.25806
INKA2 inka box actin regulator 2 2.25666
CEP170B centrosomal protein 170B 2.25653
TCP11L1 t-complex 11, testis-specific-like 1 2.25535
KAT2A K(lysine) acetyltransferase 2A 2.25356
TNS4 tensin 4 2.25325
RIC8A RIC8 guanine nucleotide exchange factor A 2.25283
UNC13D unc-13 homolog D (C. elegans) 2.25138
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2.24843
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.24648
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.24518
CIDEC cell death-inducing DFFA-like effector c 2.23927
ARID5A AT rich interactive domain 5A (MRF1-like) 2.23839
GBP2 guanylate binding protein 2, interferon-inducible 2.23586
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.23377
ATG4B autophagy related 4B, cysteine peptidase 2.23203
RIN1 Ras and Rab interactor 1 2.22902
MTCL1 microtubule crosslinking factor 1 2.22839
MARCHF5 membrane associated ring-CH-type finger 5 2.22696
PHF11 PHD finger protein 11 2.22659
SLIT2 slit homolog 2 (Drosophila) 2.22605
EPAS1 endothelial PAS domain protein 1 2.22542
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.22421
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.22403
ZNF419 zinc finger protein 419 2.22397
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.22346
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.22012
BMP1 bone morphogenetic protein 1 2.21507
CSK c-src tyrosine kinase 2.21147
EVC Ellis van Creveld protein 2.21033
SFTPA2 surfactant protein A2 2.20794
CYB561D2 cytochrome b561 family, member D2 2.20563
ZFHX3 zinc finger homeobox 3 2.20542
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.20048
PEX13 peroxisomal biogenesis factor 13 2.19956
MMP24OS MMP24 opposite strand 2.19142
GADD45A growth arrest and DNA-damage-inducible, alpha 2.18999
SGSH N-sulfoglucosamine sulfohydrolase 2.18919
LPIN2 lipin 2 2.18796
SLC35F2 solute carrier family 35, member F2 2.18778
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.18734
NBEAL2 neurobeachin-like 2 2.18728
MOSPD1 motile sperm domain containing 1 2.18524
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.18461
CATSPERH catsper channel auxiliary subunit eta 2.18395
KIZ kizuna centrosomal protein 2.18222
ZNF574 zinc finger protein 574 2.18154
MOSPD3 motile sperm domain containing 3 2.1801
CSRNP2 cysteine-serine-rich nuclear protein 2 2.17758
OXCT2 3-oxoacid CoA transferase 2 2.17654
HLA-A major histocompatibility complex, class I, A 2.17301
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.17146
CPLX3 complexin 3 2.17067
KEAP1 kelch-like ECH-associated protein 1 2.17015
DLX2 distal-less homeobox 2 2.16906
ATP13A2 ATPase type 13A2 2.16565
OFD1 oral-facial-digital syndrome 1 2.16181
MICALL2 MICAL-like 2 2.16174
FLNA filamin A, alpha 2.1598
TRIM8 tripartite motif containing 8 2.15494
MARK4 MAP/microtubule affinity-regulating kinase 4 2.15379
PROCR protein C receptor, endothelial 2.15326
RIC8B RIC8 guanine nucleotide exchange factor B 2.15316
R3HDM4 R3H domain containing 4 2.15265
ECE1 endothelin converting enzyme 1 2.15036
VPS9D1 VPS9 domain containing 1 2.15009
BEST1 bestrophin 1 2.15006
ITSN2 intersectin 2 2.14835
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.1482
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.14762
COQ4 coenzyme Q4 2.14691
TOLLIP toll interacting protein 2.14615
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.14456
IFI27 interferon, alpha-inducible protein 27 2.14368
TMC7 transmembrane channel-like 7 2.14289
ZC3H12A zinc finger CCCH-type containing 12A 2.13954
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.13845
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.13761
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.13387
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.13365
ZNF562 zinc finger protein 562 2.1333
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.13044
ZNF274 zinc finger protein 274 2.12986
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 2.12725
SAMD9 sterile alpha motif domain containing 9 2.12687
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.12647
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.12421
TNK1 tyrosine kinase, non-receptor, 1 2.12342
CREBL2 cAMP responsive element binding protein-like 2 2.1227
PLD2 phospholipase D2 2.12113
FOXO1 forkhead box O1 2.12066
PALLD palladin, cytoskeletal associated protein 2.11906
TMEM140 transmembrane protein 140 2.11903
CLIP1 CAP-GLY domain containing linker protein 1 2.11766
DST dystonin 2.11553
SFXN3 sideroflexin 3 2.11511
UFM1 ubiquitin-fold modifier 1 2.11473
MATN4 matrilin 4 2.11065
BCL10 B-cell CLL/lymphoma 10 2.10994
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.1098
LYPD3 LY6/PLAUR domain containing 3 2.10808
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.10689
TMEM106B transmembrane protein 106B 2.10686
ASB6 ankyrin repeat and SOCS box containing 6 2.10493
TMEM50A transmembrane protein 50A 2.09852
PHF20L1 PHD finger protein 20-like 1 2.09828
AHNAK2 AHNAK nucleoprotein 2 2.09705
PLXNA1 plexin A1 2.09625
CLK3 CDC-like kinase 3 2.09613
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.09556
ENAH enabled homolog (Drosophila) 2.09231
AKR1C3 aldo-keto reductase family 1, member C3 2.08953
POLH polymerase (DNA directed), eta 2.08689
ZNF226 zinc finger protein 226 2.08475
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 2.08438
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.08249
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.08154
ATF3 activating transcription factor 3 2.08093
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 2.07729
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.0762
PMP22 peripheral myelin protein 22 2.07612
TSG101 tumor susceptibility 101 2.07605
DGKA diacylglycerol kinase, alpha 80kDa 2.07556
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.07538
SUGP1 SURP and G patch domain containing 1 2.07136
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.06974
CXCL13 chemokine (C-X-C motif) ligand 13 2.06874
EIF1B eukaryotic translation initiation factor 1B 2.06832
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.06219
TMEM40 transmembrane protein 40 2.06092
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.05982
PEX16 peroxisomal biogenesis factor 16 2.05949
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.0576
RNF11 ring finger protein 11 2.0547
PRB3 proline-rich protein BstNI subfamily 3 2.05443
WDR1 WD repeat domain 1 2.0544
KIFBP kinesin family binding protein 2.05437
SEC24C SEC24 family member C 2.05389
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.05328
BBX bobby sox homolog (Drosophila) 2.05294
TSPY2 testis specific protein, Y-linked 2 2.04971
LHB luteinizing hormone beta polypeptide 2.04931
MBNL2 muscleblind-like splicing regulator 2 2.04912
CLTC clathrin, heavy chain (Hc) 2.04663
RHOD ras homolog family member D 2.04294
EML3 echinoderm microtubule associated protein like 3 2.04252
NPTN neuroplastin 2.04191
TMEM132A transmembrane protein 132A 2.03987
TBC1D2 TBC1 domain family, member 2 2.0357
B3GAT3 beta-1,3-glucuronyltransferase 3 2.03431
POLGARF POLG alternative reading frame 2.03415
DNASE1L1 deoxyribonuclease I-like 1 2.03392
KLC1 kinesin light chain 1 2.03134
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 2.02413
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.02296
GP1BA glycoprotein Ib (platelet), alpha polypeptide 2.01951
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.0189
ACVR1 activin A receptor, type I 2.01884
EFNB1 ephrin-B1 2.01639
LTK leukocyte receptor tyrosine kinase 2.0155
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 2.01516
CD9 CD9 molecule 2.01447
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.01387
FAM13B family with sequence similarity 13, member B 2.01353
THBS3 thrombospondin 3 2.01272
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.0122
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.01175
ADGRD2 adhesion G protein-coupled receptor D2 2.01162
TYK2 tyrosine kinase 2 2.01116
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.01087
P3H3 prolyl 3-hydroxylase 3 2.00989
MYT1 myelin transcription factor 1 2.00985
MED15 mediator complex subunit 15 2.00819
RABGAP1 RAB GTPase activating protein 1 2.00621
TM4SF1 transmembrane 4 L six family member 1 2.00601
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.00517
NPIPB6 nuclear pore complex interacting protein family, member B6 2.00445
ZNF337 zinc finger protein 337 2.00435
RASAL2 RAS protein activator like 2 2.00377
BDKRB2 bradykinin receptor B2 2.00371
TUFT1 tuftelin 1 2.00038

decreased expression

Symbol Name Standardized Value
MCM3 minichromosome maintenance complex component 3 -8.83161
STMN1 stathmin 1 -6.67647
NUP85 nucleoporin 85kDa -6.66479
CCNA2 cyclin A2 -6.5413
CDC20 cell division cycle 20 -6.21779
BIRC5 baculoviral IAP repeat containing 5 -6.16108
LBR lamin B receptor -6.15756
MCM6 minichromosome maintenance complex component 6 -6.15488
KIF15 kinesin family member 15 -6.1005
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -5.84106
LMNB1 lamin B1 -5.75016
UBE2C ubiquitin-conjugating enzyme E2C -5.73773
CCNB2 cyclin B2 -5.54824
HADH hydroxyacyl-CoA dehydrogenase -5.53691
TRMT5 tRNA methyltransferase 5 -5.49197
KIF4A kinesin family member 4A -5.48605
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -5.40395
RFC4 replication factor C (activator 1) 4, 37kDa -5.37847
SPC25 SPC25, NDC80 kinetochore complex component -5.36602
OIP5 Opa interacting protein 5 -5.34544
CDT1 chromatin licensing and DNA replication factor 1 -5.2994
PLK1 polo-like kinase 1 -5.288
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -5.25163
ZWINT ZW10 interacting kinetochore protein -5.22602
PROM1 prominin 1 -5.22302
KIF20A kinesin family member 20A -5.19883
GINS1 GINS complex subunit 1 (Psf1 homolog) -5.1941
CDC45 cell division cycle 45 -5.14007
TK1 thymidine kinase 1, soluble -5.13739
MCM5 minichromosome maintenance complex component 5 -5.12941
NCAPG2 non-SMC condensin II complex, subunit G2 -5.07306
GINS2 GINS complex subunit 2 (Psf2 homolog) -5.01403
CDK1 cyclin-dependent kinase 1 -5.0138
NEIL3 nei endonuclease VIII-like 3 (E. coli) -4.91216
AURKB aurora kinase B -4.88797
TOP2A topoisomerase (DNA) II alpha 170kDa -4.88787
PSRC1 proline/serine-rich coiled-coil 1 -4.87819
HMMR hyaluronan-mediated motility receptor (RHAMM) -4.79778
CCNB1 cyclin B1 -4.79204
MCM7 minichromosome maintenance complex component 7 -4.7839
DSCC1 DNA replication and sister chromatid cohesion 1 -4.76521
MIS18A MIS18 kinetochore protein A -4.7605
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.75463
NUCB2 nucleobindin 2 -4.73275
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.72869
HAT1 histone acetyltransferase 1 -4.70274
H2AX H2A.X variant histone -4.6594
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.64157
MCM4 minichromosome maintenance complex component 4 -4.60603
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.6032
ELOVL6 ELOVL fatty acid elongase 6 -4.60016
RFC3 replication factor C (activator 1) 3, 38kDa -4.56887
USP1 ubiquitin specific peptidase 1 -4.52167
PYCR1 pyrroline-5-carboxylate reductase 1 -4.50674
CDC23 cell division cycle 23 -4.48647
HMGN2 high mobility group nucleosomal binding domain 2 -4.47815
HMGB2 high mobility group box 2 -4.42975
PECR peroxisomal trans-2-enoyl-CoA reductase -4.42889
SNRPA small nuclear ribonucleoprotein polypeptide A -4.40982
MCM10 minichromosome maintenance complex component 10 -4.40694
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.40117
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.39949
MRPL48 mitochondrial ribosomal protein L48 -4.39838
ARHGAP11A Rho GTPase activating protein 11A -4.39615
DCK deoxycytidine kinase -4.3919
MTFR1 mitochondrial fission regulator 1 -4.38979
UXT ubiquitously-expressed, prefoldin-like chaperone -4.38866
RPA3 replication protein A3, 14kDa -4.38405
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -4.34756
KIF18B kinesin family member 18B -4.32542
DUT deoxyuridine triphosphatase -4.29958
ASF1B anti-silencing function 1B histone chaperone -4.2943
PGM1 phosphoglucomutase 1 -4.2852
TRIP13 thyroid hormone receptor interactor 13 -4.28416
DEPDC1 DEP domain containing 1 -4.24236
KIF11 kinesin family member 11 -4.23859
AUNIP aurora kinase A and ninein interacting protein -4.23002
MSH2 mutS homolog 2 -4.22768
GGCT gamma-glutamylcyclotransferase -4.22001
PRC1 protein regulator of cytokinesis 1 -4.20224
FIRRM FIGNL1 interacting regulator of recombination and mitosis -4.16078
TMEM97 transmembrane protein 97 -4.15527
FEN1 flap structure-specific endonuclease 1 -4.15344
CDC6 cell division cycle 6 -4.14979
ELP4 elongator acetyltransferase complex subunit 4 -4.12295
WDR76 WD repeat domain 76 -4.10371
NUSAP1 nucleolar and spindle associated protein 1 -4.10128
TMPO thymopoietin -4.08406
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -4.07946
CFAP20 cilia and flagella associated protein 20 -4.07459
GPHN gephyrin -4.07395
FBXO5 F-box protein 5 -4.05562
NLRP4 NLR family, pyrin domain containing 4 -4.05377
MRPL58 mitochondrial ribosomal protein L58 -4.0415
CDC7 cell division cycle 7 -4.03663
SPAG5 sperm associated antigen 5 -3.98693
TTK TTK protein kinase -3.9747
NDC1 NDC1 transmembrane nucleoporin -3.96368
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.96203
RNF130 ring finger protein 130 -3.95436
PPIH peptidylprolyl isomerase H (cyclophilin H) -3.95211
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -3.94791
MRPL11 mitochondrial ribosomal protein L11 -3.93814
E2F8 E2F transcription factor 8 -3.92438
ALDOC aldolase C, fructose-bisphosphate -3.89756
SKA1 spindle and kinetochore associated complex subunit 1 -3.88312
PLK4 polo-like kinase 4 -3.87587
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.86362
DHFR dihydrofolate reductase -3.85454
MRPL16 mitochondrial ribosomal protein L16 -3.85174
MTERF3 mitochondrial transcription termination factor 3 -3.84674
DET1 de-etiolated homolog 1 (Arabidopsis) -3.84273
NASP nuclear autoantigenic sperm protein (histone-binding) -3.84082
ASS1 argininosuccinate synthase 1 -3.8312
FOXM1 forkhead box M1 -3.81254
CDC25C cell division cycle 25C -3.79865
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -3.78793
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.78451
HPRT1 hypoxanthine phosphoribosyltransferase 1 -3.76864
NCAPD2 non-SMC condensin I complex, subunit D2 -3.76
APOH apolipoprotein H (beta-2-glycoprotein I) -3.75522
RFC2 replication factor C (activator 1) 2, 40kDa -3.7371
MRPS7 mitochondrial ribosomal protein S7 -3.72595
EXO1 exonuclease 1 -3.70251
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.69709
NCAPH non-SMC condensin I complex, subunit H -3.6916
EXOSC8 exosome component 8 -3.68745
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -3.67768
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.67493
BRCA1 breast cancer 1, early onset -3.6734
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.66578
CENPA centromere protein A -3.65185
VRK1 vaccinia related kinase 1 -3.64818
RACGAP1 Rac GTPase activating protein 1 -3.63807
FANCI Fanconi anemia, complementation group I -3.6303
FBL fibrillarin -3.61937
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.61592
TPX2 TPX2, microtubule-associated -3.61067
PRIM1 primase, DNA, polypeptide 1 (49kDa) -3.60796
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -3.59877
CENPQ centromere protein Q -3.59025
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -3.58307
BORA bora, aurora kinase A activator -3.56581
ATAD2 ATPase family, AAA domain containing 2 -3.56285
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.56077
PHGDH phosphoglycerate dehydrogenase -3.56058
TOPBP1 topoisomerase (DNA) II binding protein 1 -3.56045
NEK2 NIMA-related kinase 2 -3.55005
TDP1 tyrosyl-DNA phosphodiesterase 1 -3.54833
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -3.54229
TIPIN TIMELESS interacting protein -3.5218
MAGEH1 melanoma antigen family H1 -3.51845
CEP57 centrosomal protein 57kDa -3.4751
PSIP1 PC4 and SFRS1 interacting protein 1 -3.47287
ZNF124 zinc finger protein 124 -3.42323
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.42239
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.41841
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -3.41574
CDK4 cyclin-dependent kinase 4 -3.38068
DPP6 dipeptidyl-peptidase 6 -3.37864
CDCA3 cell division cycle associated 3 -3.37326
CENPU centromere protein U -3.36776
CSE1L CSE1 chromosome segregation 1-like (yeast) -3.36626
MPC2 mitochondrial pyruvate carrier 2 -3.36459
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.36413
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.3625
OPCML opioid binding protein/cell adhesion molecule-like -3.35887
COQ3 coenzyme Q3 methyltransferase -3.35637
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.35282
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.3238
CENPE centromere protein E, 312kDa -3.31404
VAV3 vav 3 guanine nucleotide exchange factor -3.2973
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.29393
HJURP Holliday junction recognition protein -3.29346
MCMBP minichromosome maintenance complex binding protein -3.28837
EBAG9 estrogen receptor binding site associated, antigen, 9 -3.27607
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -3.27223
DCP2 decapping mRNA 2 -3.25308
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.25014
KIF14 kinesin family member 14 -3.24702
UNG uracil-DNA glycosylase -3.24676
SIVA1 SIVA1, apoptosis-inducing factor -3.2393
PIMREG PICALM interacting mitotic regulator -3.23836
ITM2C integral membrane protein 2C -3.23773
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -3.23105
LIAS lipoic acid synthetase -3.22595
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.22434
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.21525
RPUSD2 RNA pseudouridylate synthase domain containing 2 -3.20787
MKI67 marker of proliferation Ki-67 -3.20027
RRM1 ribonucleotide reductase M1 -3.19905
THEM6 thioesterase superfamily member 6 -3.19649
NDC80 NDC80 kinetochore complex component -3.17532
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.17305
ASRGL1 asparaginase like 1 -3.17087
ZDHHC4 zinc finger, DHHC-type containing 4 -3.16794
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.1604
IFITM1 interferon induced transmembrane protein 1 -3.15197
PBK PDZ binding kinase -3.15194
CETN3 centrin, EF-hand protein, 3 -3.15144
NUP37 nucleoporin 37kDa -3.14685
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.14645
MRPL12 mitochondrial ribosomal protein L12 -3.1434
FANCC Fanconi anemia, complementation group C -3.1364
UBA2 ubiquitin-like modifier activating enzyme 2 -3.13595
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.13278
XYLT1 xylosyltransferase I -3.13223
HMGN1 high mobility group nucleosome binding domain 1 -3.13152
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -3.12925
ADSL adenylosuccinate lyase -3.12051
CKS1B CDC28 protein kinase regulatory subunit 1B -3.11909
ANAPC15 anaphase promoting complex subunit 15 -3.11893
E2F1 E2F transcription factor 1 -3.11582
SDF2L1 stromal cell-derived factor 2-like 1 -3.10636
KNTC1 kinetochore associated 1 -3.10452
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.08939
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -3.08384
ORC3 origin recognition complex, subunit 3 -3.08359
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -3.08127
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -3.07888
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.07552
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -3.07446
ENOPH1 enolase-phosphatase 1 -3.06727
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.06475
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -3.0626
RMI1 RecQ mediated genome instability 1 -3.05575
BCCIP BRCA2 and CDKN1A interacting protein -3.052
DSN1 DSN1, MIS12 kinetochore complex component -3.0507
CERS1 ceramide synthase 1 -3.04943
DBF4 DBF4 zinc finger -3.04525
PEX2 peroxisomal biogenesis factor 2 -3.04242
GAS2 growth arrest-specific 2 -3.03141
GPN3 GPN-loop GTPase 3 -3.03117
ZNF16 zinc finger protein 16 -3.02184
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -3.01416
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -3.01412
MSH6 mutS homolog 6 -3.00827
RAD51AP1 RAD51 associated protein 1 -3.00813
PARPBP PARP1 binding protein -3.00715
MED28 mediator complex subunit 28 -3.00648
AURKA aurora kinase A -3.006
NT5DC2 5'-nucleotidase domain containing 2 -3.00525
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.99438
KIF18A kinesin family member 18A -2.98999
RGS7 regulator of G-protein signaling 7 -2.98614
SEPHS1 selenophosphate synthetase 1 -2.98544
MELK maternal embryonic leucine zipper kinase -2.98002
SOAT2 sterol O-acyltransferase 2 -2.97824
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.97626
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.97422
CENPM centromere protein M -2.97312
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.96977
CENPS-CORT CENPS-CORT readthrough -2.96467
HAUS4 HAUS augmin-like complex, subunit 4 -2.96457
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -2.95952
SRBD1 S1 RNA binding domain 1 -2.95444
VWA1 von Willebrand factor A domain containing 1 -2.95216
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.9516
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.9453
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.94361
NTAQ1 N-terminal glutamine amidase 1 -2.94213
STOML2 stomatin (EPB72)-like 2 -2.93515
RAD51 RAD51 recombinase -2.93056
SQLE squalene epoxidase -2.9288
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.92209
RFWD3 ring finger and WD repeat domain 3 -2.91863
FZD4 frizzled class receptor 4 -2.91657
NUP54 nucleoporin 54kDa -2.9158
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.91317
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.90947
NUP155 nucleoporin 155kDa -2.90914
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -2.90766
RBM14-RBM4 RBM14-RBM4 readthrough -2.89766
FAM200C family with sequence similarity 200 member C -2.89675
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.89513
SH3D19 SH3 domain containing 19 -2.88763
RAD54B RAD54 homolog B (S. cerevisiae) -2.88541
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.88432
CDKN3 cyclin-dependent kinase inhibitor 3 -2.88365
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.88268
SMC3 structural maintenance of chromosomes 3 -2.88106
TEDC2 tubulin epsilon and delta complex 2 -2.87905
ECI1 enoyl-CoA delta isomerase 1 -2.87665
MNS1 meiosis-specific nuclear structural 1 -2.87629
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.86933
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.86593
CBX5 chromobox homolog 5 -2.86274
H2AZ2 H2A.Z variant histone 2 -2.85669
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.84589
ABHD10 abhydrolase domain containing 10 -2.84282
RBMX RNA binding motif protein, X-linked -2.83817
AGGF1 angiogenic factor with G patch and FHA domains 1 -2.83693
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.82998
SRR serine racemase -2.82729
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.81938
KLHL26 kelch-like family member 26 -2.81472
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.81017
PTTG1 pituitary tumor-transforming 1 -2.80611
RBM12B RNA binding motif protein 12B -2.80119
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.7997
PLEKHS1 pleckstrin homology domain containing, family S member 1 -2.79834
EIF3K eukaryotic translation initiation factor 3, subunit K -2.79723
SHCBP1 SHC SH2-domain binding protein 1 -2.7899
RBL1 retinoblastoma-like 1 -2.78454
MTF2 metal response element binding transcription factor 2 -2.77579
CXCL5 chemokine (C-X-C motif) ligand 5 -2.77507
RIDA reactive intermediate imine deaminase A homolog -2.76689
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -2.7654
ADI1 acireductone dioxygenase 1 -2.76313
PTDSS1 phosphatidylserine synthase 1 -2.7541
SLBP stem-loop binding protein -2.75258
NSD2 nuclear receptor binding SET domain protein 2 -2.75199
KIF22 kinesin family member 22 -2.75185
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.74917
CDK2 cyclin-dependent kinase 2 -2.74826
H2AZ1 H2A.Z variant histone 1 -2.74501
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.74412
PPID peptidylprolyl isomerase D -2.74192
FZD7 frizzled class receptor 7 -2.73676
PXMP2 peroxisomal membrane protein 2, 22kDa -2.73416
PLIN2 perilipin 2 -2.73351
TMEM243 transmembrane protein 243, mitochondrial -2.73336
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.73135
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.73085
DONSON downstream neighbor of SON -2.72832
S100B S100 calcium binding protein B -2.72756
USP46 ubiquitin specific peptidase 46 -2.72548
ERCC6L excision repair cross-complementation group 6-like -2.72295
CER1 cerberus 1, DAN family BMP antagonist -2.72238
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.72159
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.72105
CALB1 calbindin 1, 28kDa -2.71916
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.71912
NUP93 nucleoporin 93kDa -2.71873
KIFC1 kinesin family member C1 -2.70986
FAM107A family with sequence similarity 107, member A -2.70726
CCNF cyclin F -2.70641
CXADR coxsackie virus and adenovirus receptor -2.7059
CD200 CD200 molecule -2.70584
ADD3 adducin 3 (gamma) -2.70453
PMP2 peripheral myelin protein 2 -2.70437
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -2.70213
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.69992
NCKIPSD NCK interacting protein with SH3 domain -2.6951
HSPA14 heat shock 70kDa protein 14 -2.69095
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.68844
AQP4 aquaporin 4 -2.68736
BRD7 bromodomain containing 7 -2.68537
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -2.68526
PTPRD protein tyrosine phosphatase, receptor type, D -2.68275
LRRC59 leucine rich repeat containing 59 -2.68202
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.67879
RNASE4 ribonuclease, RNase A family, 4 -2.67827
VASH2 vasohibin 2 -2.67673
SNRPF small nuclear ribonucleoprotein polypeptide F -2.67672
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -2.67394
ARHGAP19 Rho GTPase activating protein 19 -2.67354
ZNF302 zinc finger protein 302 -2.67324
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.67273
PCLAF PCNA clamp associated factor -2.67095
MRPS27 mitochondrial ribosomal protein S27 -2.66355
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.6589
HMBS hydroxymethylbilane synthase -2.65214
ORC6 origin recognition complex, subunit 6 -2.6501
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.6438
IFITM2 interferon induced transmembrane protein 2 -2.64089
SFXN1 sideroflexin 1 -2.6346
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.62605
PARP2 poly (ADP-ribose) polymerase 2 -2.62451
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.62153
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.61793
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.61729
CEP192 centrosomal protein 192kDa -2.61429
TMEM267 transmembrane protein 267 -2.6138
ADGRL3 adhesion G protein-coupled receptor L3 -2.6072
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.60568
IFITM3 interferon induced transmembrane protein 3 -2.60541
CDC25A cell division cycle 25A -2.60392
TSPAN7 tetraspanin 7 -2.60354
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.60097
SPRY2 sprouty homolog 2 (Drosophila) -2.59978
AK4 adenylate kinase 4 -2.5995
TEAD4 TEA domain family member 4 -2.59441
IPO5 importin 5 -2.58889
ATAD5 ATPase family, AAA domain containing 5 -2.58784
PRDX4 peroxiredoxin 4 -2.56693
ERI2 ERI1 exoribonuclease family member 2 -2.56568
CEP55 centrosomal protein 55kDa -2.56535
PROS1 protein S (alpha) -2.5472
FABP7 fatty acid binding protein 7, brain -2.54491
USP39 ubiquitin specific peptidase 39 -2.54436
SEPTIN7 septin 7 -2.54362
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.54078
CASP8AP2 caspase 8 associated protein 2 -2.53883
COG2 component of oligomeric golgi complex 2 -2.53867
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.53844
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -2.53638
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -2.52491
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.52267
SKI SKI proto-oncogene -2.52097
NEUROD1 neuronal differentiation 1 -2.52022
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.51865
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.5174
HAUS7 HAUS augmin-like complex, subunit 7 -2.51718
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.51689
NUP205 nucleoporin 205kDa -2.51625
ARMCX5 armadillo repeat containing, X-linked 5 -2.51429
CTNND2 catenin (cadherin-associated protein), delta 2 -2.51331
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.50938
MID1IP1 MID1 interacting protein 1 -2.50532
METRN meteorin, glial cell differentiation regulator -2.49891
TMEM70 transmembrane protein 70 -2.49635
FANCG Fanconi anemia, complementation group G -2.49457
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.49193
HELLS helicase, lymphoid-specific -2.49172
NCAPD3 non-SMC condensin II complex, subunit D3 -2.49087
APOA2 apolipoprotein A-II -2.49031
GORASP2 golgi reassembly stacking protein 2, 55kDa -2.48777
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.48508
SRD5A3 steroid 5 alpha-reductase 3 -2.48037
ANKRD49 ankyrin repeat domain 49 -2.47971
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.479
NREP neuronal regeneration related protein -2.47746
MYO10 myosin X -2.4768
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.4767
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.47401
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.47399
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.47156
CNPY3 canopy FGF signaling regulator 3 -2.47102
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.46978
GJB1 gap junction protein, beta 1, 32kDa -2.46879
EPCIP exosomal polycystin 1 interacting protein -2.46574
DLAT dihydrolipoamide S-acetyltransferase -2.46359
HMGA2 high mobility group AT-hook 2 -2.46018
RAB33B RAB33B, member RAS oncogene family -2.4549
DPYD dihydropyrimidine dehydrogenase -2.45244
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.44933
IREB2 iron-responsive element binding protein 2 -2.44931
NUP43 nucleoporin 43kDa -2.44658
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -2.44589
TLR5 toll-like receptor 5 -2.44491
ARMC1 armadillo repeat containing 1 -2.44294
COL1A2 collagen, type I, alpha 2 -2.44217
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.44148
LRRC40 leucine rich repeat containing 40 -2.43882
FAIM Fas apoptotic inhibitory molecule -2.43641
TUBGCP4 tubulin, gamma complex associated protein 4 -2.4303
CDK7 cyclin-dependent kinase 7 -2.42825
TRIM28 tripartite motif containing 28 -2.42825
PPA2 pyrophosphatase (inorganic) 2 -2.42719
LETMD1 LETM1 domain containing 1 -2.42704
CHEK2 checkpoint kinase 2 -2.42704
GPR19 G protein-coupled receptor 19 -2.42523
RBM42 RNA binding motif protein 42 -2.42502
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.42363
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.42347
RAB15 RAB15, member RAS oncogene family -2.42323
RUSC1 RUN and SH3 domain containing 1 -2.42069
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.42005
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.41904
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.4189
DCAF16 DDB1 and CUL4 associated factor 16 -2.41652
MAK16 MAK16 homolog (S. cerevisiae) -2.4152
TMEM183A transmembrane protein 183A -2.41379
RBBP5 retinoblastoma binding protein 5 -2.41317
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.41265
RPL22 ribosomal protein L22 -2.41183
URI1 URI1, prefoldin-like chaperone -2.40177
ZFAND1 zinc finger, AN1-type domain 1 -2.4016
COPZ1 coatomer protein complex, subunit zeta 1 -2.39892
RFXAP regulatory factor X-associated protein -2.39844
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.39802
HMGB1 high mobility group box 1 -2.39569
ANAPC1 anaphase promoting complex subunit 1 -2.39305
CS citrate synthase -2.39259
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.39257
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.39184
C2CD5 C2 calcium-dependent domain containing 5 -2.39042
TCERG1 transcription elongation regulator 1 -2.39012
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.38767
TIMELESS timeless circadian clock -2.3859
GCAT glycine C-acetyltransferase -2.38261
GSTCD glutathione S-transferase, C-terminal domain containing -2.38198
SRP9 signal recognition particle 9kDa -2.38145
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.38144
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.37915
ANAPC5 anaphase promoting complex subunit 5 -2.37314
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.37313
RALY RALY heterogeneous nuclear ribonucleoprotein -2.37232
ADH6 alcohol dehydrogenase 6 (class V) -2.37194
RWDD3 RWD domain containing 3 -2.37162
RPIA ribose 5-phosphate isomerase A -2.37107
QSER1 glutamine and serine rich 1 -2.37022
FN3KRP fructosamine 3 kinase related protein -2.36969
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.36897
EXOSC9 exosome component 9 -2.36809
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -2.3678
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.36478
COL21A1 collagen, type XXI, alpha 1 -2.36279
TUBD1 tubulin, delta 1 -2.36049
FOCAD focadhesin -2.3586
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.35853
HDAC3 histone deacetylase 3 -2.35736
SCRG1 stimulator of chondrogenesis 1 -2.35548
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -2.35224
MRPL17 mitochondrial ribosomal protein L17 -2.34836
OXR1 oxidation resistance 1 -2.34832
NXT1 nuclear transport factor 2-like export factor 1 -2.34713
NPM3 nucleophosmin/nucleoplasmin 3 -2.34439
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -2.34429
SMIM8 small integral membrane protein 8 -2.33706
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -2.33398
ACTL6A actin-like 6A -2.33376
ASTE1 asteroid homolog 1 (Drosophila) -2.33356
NEK4 NIMA-related kinase 4 -2.32834
DEK DEK proto-oncogene -2.32494
SSRP1 structure specific recognition protein 1 -2.32492
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.32264
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.32238
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.31892
C4BPA complement component 4 binding protein, alpha -2.3185
RIT2 Ras-like without CAAX 2 -2.31791
RANBP1 RAN binding protein 1 -2.31765
AZIN1 antizyme inhibitor 1 -2.31628
HIRA histone cell cycle regulator -2.31502
RRM2 ribonucleotide reductase M2 -2.3145
HAUS3 HAUS augmin-like complex, subunit 3 -2.3111
GOLT1B golgi transport 1B -2.31083
DHCR7 7-dehydrocholesterol reductase -2.30842
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.30386
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.30366
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.30351
GALP galanin-like peptide -2.3034
EIF4A3 eukaryotic translation initiation factor 4A3 -2.30318
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.30251
CENPI centromere protein I -2.30234
AHCY adenosylhomocysteinase -2.29938
EMID1 EMI domain containing 1 -2.29647
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.29557
XPO7 exportin 7 -2.29549
C5 complement component 5 -2.29317
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.29001
METTL18 methyltransferase like 18 -2.28877
B3GAT1 beta-1,3-glucuronyltransferase 1 -2.28208
PGAP2 post-GPI attachment to proteins 2 -2.28085
EIF3E eukaryotic translation initiation factor 3, subunit E -2.2786
GPRC5C G protein-coupled receptor, class C, group 5, member C -2.27843
RABL3 RAB, member of RAS oncogene family-like 3 -2.2784
OBI1 ORC ubiquitin ligase 1 -2.2736
NCAM2 neural cell adhesion molecule 2 -2.26962
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.26911
GDF10 growth differentiation factor 10 -2.26839
HMGXB4 HMG box domain containing 4 -2.26834
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.26499
JAM3 junctional adhesion molecule 3 -2.26303
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.25951
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.25903
POT1 protection of telomeres 1 -2.25714
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.25346
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.25245
SRP72 signal recognition particle 72kDa -2.25204
GALK2 galactokinase 2 -2.24983
CENPX centromere protein X -2.24795
C1QBP complement component 1, q subcomponent binding protein -2.24626
SRSF2 serine/arginine-rich splicing factor 2 -2.24414
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.24031
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -2.23884
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.23854
ZNF83 zinc finger protein 83 -2.23761
KCTD11 potassium channel tetramerization domain containing 11 -2.23262
RPN2 ribophorin II -2.23167
IL10RB interleukin 10 receptor, beta -2.23163
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.23096
NDP Norrie disease (pseudoglioma) -2.22899
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -2.22841
CHL1 cell adhesion molecule L1-like -2.22721
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -2.22488
ZBTB10 zinc finger and BTB domain containing 10 -2.22222
LIPC lipase, hepatic -2.22165
TMEM242 transmembrane protein 242 -2.21985
SATB2 SATB homeobox 2 -2.21895
NAGA N-acetylgalactosaminidase, alpha- -2.21861
CRYM crystallin, mu -2.21848
MANEA mannosidase, endo-alpha -2.21696
TF transferrin -2.21556
NUP107 nucleoporin 107kDa -2.21515
AKR1D1 aldo-keto reductase family 1, member D1 -2.21434
SRSF3 serine/arginine-rich splicing factor 3 -2.21433
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 -2.21425
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.21355
CPOX coproporphyrinogen oxidase -2.21089
IL7 interleukin 7 -2.21009
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.20905
IKZF2 IKAROS family zinc finger 2 (Helios) -2.2063
DENND10 DENN domain containing 10 -2.20615
PRKCB protein kinase C, beta -2.20589
CAMK4 calcium/calmodulin-dependent protein kinase IV -2.20537
SYNGR2 synaptogyrin 2 -2.20531
NOL9 nucleolar protein 9 -2.20453
RNASE6 ribonuclease, RNase A family, k6 -2.20255
CTCF CCCTC-binding factor (zinc finger protein) -2.20193
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.20121
POLR1E polymerase (RNA) I polypeptide E, 53kDa -2.19869
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.19691
DEPTOR DEP domain containing MTOR-interacting protein -2.19661
PTPRG protein tyrosine phosphatase, receptor type, G -2.19585
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.19434
PPT1 palmitoyl-protein thioesterase 1 -2.19017
SNTG1 syntrophin, gamma 1 -2.189
PGR progesterone receptor -2.1878
CPB2 carboxypeptidase B2 (plasma) -2.18624
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.18581
CXCL6 chemokine (C-X-C motif) ligand 6 -2.18328
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.18086
PELI2 pellino E3 ubiquitin protein ligase family member 2 -2.17909
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.17599
CRIPTO3 cripto, EGF-CFC family member 3 -2.17464
CDCA4 cell division cycle associated 4 -2.17055
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -2.17035
PLPPR1 phospholipid phosphatase related 1 -2.17019
ZNF552 zinc finger protein 552 -2.17002
NUP133 nucleoporin 133kDa -2.1696
PDIA6 protein disulfide isomerase family A, member 6 -2.16897
ZWILCH zwilch kinetochore protein -2.16827
KCNK5 potassium channel, two pore domain subfamily K, member 5 -2.16596
SPRY4 sprouty homolog 4 (Drosophila) -2.16585
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.16461
CDCA8 cell division cycle associated 8 -2.16445
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.16434
GLDC glycine dehydrogenase (decarboxylating) -2.16404
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -2.15965
MRPL23 mitochondrial ribosomal protein L23 -2.15956
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 -2.158
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.1546
ABI3BP ABI family, member 3 (NESH) binding protein -2.15443
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.1516
SLC2A4RG SLC2A4 regulator -2.1503
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -2.14977
CETN2 centrin, EF-hand protein, 2 -2.1476
CHEK1 checkpoint kinase 1 -2.14726
RPAIN RPA interacting protein -2.14712
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.14638
ORC4 origin recognition complex, subunit 4 -2.14593
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -2.14559
MSMO1 methylsterol monooxygenase 1 -2.14499
SAP30BP SAP30 binding protein -2.14324
DELE1 DAP3 binding cell death enhancer 1 -2.14287
TRA2B transformer 2 beta homolog (Drosophila) -2.14268
FAF1 Fas (TNFRSF6) associated factor 1 -2.14122
STIL SCL/TAL1 interrupting locus -2.14019
POLK polymerase (DNA directed) kappa -2.14016
THAP7 THAP domain containing 7 -2.13915
NOL11 nucleolar protein 11 -2.13633
TYRO3 TYRO3 protein tyrosine kinase -2.1345
PDIA4 protein disulfide isomerase family A, member 4 -2.13272
TRAPPC4 trafficking protein particle complex 4 -2.1317
TMEM39A transmembrane protein 39A -2.13163
TASP1 taspase, threonine aspartase, 1 -2.13116
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.12486
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.12269
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.12243
NFYB nuclear transcription factor Y, beta -2.11762
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.11709
HBG1 hemoglobin, gamma A -2.11681
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.11502
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.11381
HSPB2 heat shock 27kDa protein 2 -2.11305
ECT2 epithelial cell transforming 2 -2.10861
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.10793
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.10771
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -2.10737
ICMT isoprenylcysteine carboxyl methyltransferase -2.10663
TMEM258 transmembrane protein 258 -2.10512
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like -2.10345
FXYD6-FXYD2 FXYD6-FXYD2 readthrough -2.1022
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.10089
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.09994
CENPN centromere protein N -2.09961
GPA33 glycoprotein A33 (transmembrane) -2.09912
NOX1 NADPH oxidase 1 -2.09698
RAB20 RAB20, member RAS oncogene family -2.09587
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 -2.09418
ZNF22 zinc finger protein 22 -2.09105
U2SURP U2 snRNP-associated SURP domain containing -2.08847
PYDC1 PYD (pyrin domain) containing 1 -2.08738
PEX11A peroxisomal biogenesis factor 11 alpha -2.08607
ANG angiogenin, ribonuclease, RNase A family, 5 -2.08444
MUC16 mucin 16, cell surface associated -2.08371
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.07924
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -2.07742
ZMYM1 zinc finger, MYM-type 1 -2.07549
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.07399
BARD1 BRCA1 associated RING domain 1 -2.07374
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.07222
PTGDS prostaglandin D2 synthase 21kDa (brain) -2.06798
FANCF Fanconi anemia, complementation group F -2.06775
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.06766
OXCT1 3-oxoacid CoA transferase 1 -2.06762
TRIL TLR4 interactor with leucine-rich repeats -2.06557
ACADL acyl-CoA dehydrogenase, long chain -2.06484
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.06452
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.06293
PPIB peptidylprolyl isomerase B (cyclophilin B) -2.06269
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.0607
TEX30 testis expressed 30 -2.06054
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.05979
NUBPL nucleotide binding protein-like -2.05541
THAP1 THAP domain containing, apoptosis associated protein 1 -2.05165
SUMO2 small ubiquitin-like modifier 2 -2.04952
RAD54L RAD54-like (S. cerevisiae) -2.04733
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -2.04518
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 -2.04163
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.04039
ATF4 activating transcription factor 4 -2.03965
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -2.03885
BRIX1 BRX1, biogenesis of ribosomes -2.03852
MCRS1 microspherule protein 1 -2.03796
NPR2 natriuretic peptide receptor 2 -2.03529
EPHX2 epoxide hydrolase 2, cytoplasmic -2.03346
NUTF2 nuclear transport factor 2 -2.03311
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.03258
SELL selectin L -2.03034
MRPS2 mitochondrial ribosomal protein S2 -2.02998
CDH19 cadherin 19, type 2 -2.02982
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.02952
TMSB15B thymosin beta 15B -2.02863
ATP5F1A ATP synthase F1 subunit alpha -2.02814
FAM20B family with sequence similarity 20, member B -2.02756
SNRPE small nuclear ribonucleoprotein polypeptide E -2.02396
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -2.02336
MIS18BP1 MIS18 binding protein 1 -2.02291
COMMD8 COMM domain containing 8 -2.0225
NUP62 nucleoporin 62kDa -2.02139
MLH1 mutL homolog 1 -2.01912
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.01786
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.01778
TPK1 thiamin pyrophosphokinase 1 -2.01583
CREB3L2 cAMP responsive element binding protein 3-like 2 -2.01552
SELENOF selenoprotein F -2.01398
POLR1G RNA polymerase I subunit G -2.01326
RHOBTB3 Rho-related BTB domain containing 3 -2.0114
TOR3A torsin family 3, member A -2.00875
IMPACT impact RWD domain protein -2.00821
VTA1 vesicle (multivesicular body) trafficking 1 -2.00696
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.00692
TACC3 transforming, acidic coiled-coil containing protein 3 -2.00626
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.00568
FABP1 fatty acid binding protein 1, liver -2.00548
DOK5 docking protein 5 -2.00343
ESRP1 epithelial splicing regulatory protein 1 -2.00307
TMEM160 transmembrane protein 160 -2.00217
ZNF107 zinc finger protein 107 -2.00151
CALML4 calmodulin-like 4 -2.00104