CRCGN015_HEPG2_48H:P24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dibenzo[a,h]pyrene 11.16 um perturbation at 48 h in HEPG2 (Carcinogenome)
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Genes

1016 genes differentially expressed following the CRCGN015_HEPG2_48H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 7.85626
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 6.03687
INPP1 inositol polyphosphate-1-phosphatase 5.6444
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.42641
TRIB1 tribbles pseudokinase 1 5.31471
RALB v-ral simian leukemia viral oncogene homolog B 5.31121
FHL2 four and a half LIM domains 2 5.20926
FSTL3 follistatin-like 3 (secreted glycoprotein) 5.20208
ABHD4 abhydrolase domain containing 4 4.98215
DDB2 damage-specific DNA binding protein 2, 48kDa 4.97275
PHLDA3 pleckstrin homology-like domain, family A, member 3 4.87689
CHIC2 cysteine-rich hydrophobic domain 2 4.83609
MICALL1 MICAL-like 1 4.79548
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.69527
BDH1 3-hydroxybutyrate dehydrogenase, type 1 4.5591
IER3 immediate early response 3 4.50206
FDXR ferredoxin reductase 4.4385
REXO2 RNA exonuclease 2 4.34459
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.26184
TP53I3 tumor protein p53 inducible protein 3 4.14237
MAPK13 mitogen-activated protein kinase 13 4.11469
TIGAR TP53 induced glycolysis regulatory phosphatase 4.09499
H2BC21 H2B clustered histone 21 4.09017
HEBP1 heme binding protein 1 4.0474
FASN fatty acid synthase 4.03786
SKIC2 SKI2 subunit of superkiller complex 4.01893
DUSP6 dual specificity phosphatase 6 4.00191
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.9151
CCDC86 coiled-coil domain containing 86 3.87275
EPHA2 EPH receptor A2 3.8193
ZMAT3 zinc finger, matrin-type 3 3.80871
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.8081
TMUB2 transmembrane and ubiquitin-like domain containing 2 3.79595
VAT1 vesicle amine transport 1 3.69588
ACOT9 acyl-CoA thioesterase 9 3.69385
FOSL1 FOS-like antigen 1 3.67958
BLCAP bladder cancer associated protein 3.67135
EPS8L2 EPS8-like 2 3.66954
DUSP14 dual specificity phosphatase 14 3.61266
XPC xeroderma pigmentosum, complementation group C 3.60574
LRP10 low density lipoprotein receptor-related protein 10 3.59404
FAT1 FAT atypical cadherin 1 3.57462
PINK1 PTEN induced putative kinase 1 3.55516
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.54646
MVP major vault protein 3.51193
TUBB6 tubulin, beta 6 class V 3.48504
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 3.4558
ASCC3 activating signal cointegrator 1 complex subunit 3 3.45391
GSDME gasdermin E 3.43367
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 3.41664
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 3.41213
SQSTM1 sequestosome 1 3.36454
ITPKC inositol-trisphosphate 3-kinase C 3.36353
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 3.35617
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 3.31781
SOX4 SRY (sex determining region Y)-box 4 3.29576
CHMP6 charged multivesicular body protein 6 3.29264
RALGDS ral guanine nucleotide dissociation stimulator 3.28701
FURIN furin (paired basic amino acid cleaving enzyme) 3.23542
SYNGR3 synaptogyrin 3 3.22397
AEN apoptosis enhancing nuclease 3.21693
LOC102724023 ES1 protein homolog, mitochondrial 3.21378
CCDC90B coiled-coil domain containing 90B 3.21153
CYTH1 cytohesin 1 3.2077
TRIP12 thyroid hormone receptor interactor 12 3.17936
UBAP1 ubiquitin associated protein 1 3.1581
STAMBP STAM binding protein 3.14802
KIFBP kinesin family binding protein 3.11695
RAB9A RAB9A, member RAS oncogene family 3.06541
GPC1 glypican 1 3.02978
MARCHF5 membrane associated ring-CH-type finger 5 3.00657
SNX11 sorting nexin 11 2.99863
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.98512
KIFC3 kinesin family member C3 2.97716
RHOC ras homolog family member C 2.97672
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.96011
DNASE1L1 deoxyribonuclease I-like 1 2.95777
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.93913
CTF1 cardiotrophin 1 2.93725
RAP1GAP RAP1 GTPase activating protein 2.92762
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.92509
SCRN1 secernin 1 2.92188
BATF basic leucine zipper transcription factor, ATF-like 2.9135
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.89281
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.88703
BECN1 beclin 1, autophagy related 2.88625
S100A3 S100 calcium binding protein A3 2.87035
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.8648
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.85327
MYH9 myosin, heavy chain 9, non-muscle 2.85287
TWF2 twinfilin actin binding protein 2 2.85243
NAV2 neuron navigator 2 2.84779
ZNF79 zinc finger protein 79 2.84521
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.84323
TUBG2 tubulin, gamma 2 2.84317
HSPA4L heat shock 70kDa protein 4-like 2.83963
CDA cytidine deaminase 2.83594
OXCT2 3-oxoacid CoA transferase 2 2.83134
YIPF3 Yip1 domain family, member 3 2.82761
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.82682
PXDC1 PX domain containing 1 2.82088
GABARAPL1 GABA(A) receptor-associated protein like 1 2.81587
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 2.80071
TXNRD1 thioredoxin reductase 1 2.79886
AVPI1 arginine vasopressin-induced 1 2.79361
ITGAV integrin, alpha V 2.78459
BCAR3 breast cancer anti-estrogen resistance 3 2.78205
PARP3 poly (ADP-ribose) polymerase family, member 3 2.7738
BBC3 BCL2 binding component 3 2.76742
TUT7 terminal uridylyl transferase 7 2.75479
TRIM8 tripartite motif containing 8 2.75395
STOM stomatin 2.74321
OSGIN1 oxidative stress induced growth inhibitor 1 2.74043
SIRT7 sirtuin 7 2.73651
TRIP4 thyroid hormone receptor interactor 4 2.73566
ATOSB atos homolog B 2.73527
ULK1 unc-51 like autophagy activating kinase 1 2.73359
IL4R interleukin 4 receptor 2.72632
CARD10 caspase recruitment domain family, member 10 2.72069
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.72004
TERF2IP telomeric repeat binding factor 2, interacting protein 2.71217
CDIP1 cell death-inducing p53 target 1 2.71172
INPPL1 inositol polyphosphate phosphatase-like 1 2.69762
CALCOCO1 calcium binding and coiled-coil domain 1 2.69566
CCDC92 coiled-coil domain containing 92 2.69474
CIDEC cell death-inducing DFFA-like effector c 2.69243
FAM50A family with sequence similarity 50, member A 2.69064
SQOR sulfide quinone oxidoreductase 2.68387
GIPC1 GIPC PDZ domain containing family, member 1 2.68182
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.67885
IGF2R insulin-like growth factor 2 receptor 2.67037
FXR2 fragile X mental retardation, autosomal homolog 2 2.66371
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.6625
PLK3 polo-like kinase 3 2.66221
RPS27L ribosomal protein S27-like 2.65947
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.65873
LIF leukemia inhibitory factor 2.65805
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.65587
SPATA20 spermatogenesis associated 20 2.65565
WBP1L WW domain binding protein 1-like 2.65216
SLC12A9 solute carrier family 12, member 9 2.64788
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.64607
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.6419
BCL10 B-cell CLL/lymphoma 10 2.63989
TFE3 transcription factor binding to IGHM enhancer 3 2.63941
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.62622
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.62594
LOC127933115 uncharacterized LOC127933115 2.62287
S100A6 S100 calcium binding protein A6 2.61205
IL32 interleukin 32 2.60286
LAP3 leucine aminopeptidase 3 2.60024
HIGD1A HIG1 hypoxia inducible domain family, member 1A 2.59254
AMPD2 adenosine monophosphate deaminase 2 2.58909
MRPL33 mitochondrial ribosomal protein L33 2.57644
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.57639
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.57351
LMNA lamin A/C 2.57132
DKKL1 dickkopf-like 1 2.57122
CEMIP2 cell migration inducing hyaluronidase 2 2.56911
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.56851
MACF1 microtubule-actin crosslinking factor 1 2.56147
AOAH acyloxyacyl hydrolase (neutrophil) 2.56014
KDM5C lysine (K)-specific demethylase 5C 2.55211
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.55179
RHOF ras homolog family member F (in filopodia) 2.54723
PFN2 profilin 2 2.54429
STX18 syntaxin 18 2.53755
RAB7A RAB7A, member RAS oncogene family 2.53717
PLSCR3 phospholipid scramblase 3 2.53125
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.52963
HSPB8 heat shock 22kDa protein 8 2.52484
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.51741
PLXNB2 plexin B2 2.51578
MIDEAS mitotic deacetylase associated SANT domain protein 2.5152
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.51499
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.51014
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.50958
ZNF185 zinc finger protein 185 (LIM domain) 2.50395
PPME1 protein phosphatase methylesterase 1 2.50329
CST3 cystatin C 2.50163
RNF103 ring finger protein 103 2.49066
ACBD4 acyl-CoA binding domain containing 4 2.48514
S100A11 S100 calcium binding protein A11 2.48196
VPS9D1 VPS9 domain containing 1 2.4799
H2AC6 H2A clustered histone 6 2.47573
TMEM131 transmembrane protein 131 2.47511
PARP12 poly (ADP-ribose) polymerase family, member 12 2.47427
CAVIN2 caveolae associated protein 2 2.47408
MARK4 MAP/microtubule affinity-regulating kinase 4 2.47127
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.46998
RNF25 ring finger protein 25 2.46811
OFD1 oral-facial-digital syndrome 1 2.46743
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.46699
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.46692
H2AC19 H2A clustered histone 19 2.46553
KEAP1 kelch-like ECH-associated protein 1 2.46294
GAK cyclin G associated kinase 2.46123
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.4608
CXCL13 chemokine (C-X-C motif) ligand 13 2.46044
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.46016
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 2.45575
PRKCD protein kinase C, delta 2.45504
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.45342
GABARAP GABA(A) receptor-associated protein 2.4531
BTG2 BTG family, member 2 2.45096
PALLD palladin, cytoskeletal associated protein 2.44888
BAAT bile acid CoA:amino acid N-acyltransferase 2.44779
KIAA0319L KIAA0319-like 2.44754
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.44699
MAP7D1 MAP7 domain containing 1 2.44132
FBRS fibrosin 2.44042
ORAI3 ORAI calcium release-activated calcium modulator 3 2.44026
PRH1 proline-rich protein HaeIII subfamily 1 2.43509
ZFAND5 zinc finger, AN1-type domain 5 2.43025
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.41571
TBX3 T-box 3 2.40812
MTARC2 mitochondrial amidoxime reducing component 2 2.40355
BAMBI BMP and activin membrane-bound inhibitor 2.40309
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.4003
MLYCD malonyl-CoA decarboxylase 2.38586
MOSPD1 motile sperm domain containing 1 2.38422
DOK4 docking protein 4 2.37797
KCTD17 potassium channel tetramerization domain containing 17 2.37778
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.37666
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.37409
JUP junction plakoglobin 2.3738
HTRA2 HtrA serine peptidase 2 2.37243
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.36937
TMEM115 transmembrane protein 115 2.36558
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.36253
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 2.35993
GMIP GEM interacting protein 2.35884
GLRX glutaredoxin (thioltransferase) 2.3561
MXD4 MAX dimerization protein 4 2.35371
AKR1C1 aldo-keto reductase family 1, member C1 2.35269
NBR1 neighbor of BRCA1 gene 1 2.34584
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.34454
DCBLD2 discoidin, CUB and LCCL domain containing 2 2.3431
ARID5A AT rich interactive domain 5A (MRF1-like) 2.34081
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.33653
ARSA arylsulfatase A 2.33421
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.33384
SOCS2 suppressor of cytokine signaling 2 2.3324
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.3277
KIZ kizuna centrosomal protein 2.31163
NPTN neuroplastin 2.31031
CAB39 calcium binding protein 39 2.31019
USB1 U6 snRNA biogenesis 1 2.30534
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.30308
POLL polymerase (DNA directed), lambda 2.30283
GP1BA glycoprotein Ib (platelet), alpha polypeptide 2.3025
ZBTB20 zinc finger and BTB domain containing 20 2.29258
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.29205
HLA-DMB major histocompatibility complex, class II, DM beta 2.28799
AKR1C3 aldo-keto reductase family 1, member C3 2.28316
ACVR1 activin A receptor, type I 2.28116
NFE2L1 nuclear factor, erythroid 2-like 1 2.27622
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 2.27457
AOX1 aldehyde oxidase 1 2.27446
PRB3 proline-rich protein BstNI subfamily 3 2.27434
SH3BP4 SH3-domain binding protein 4 2.27035
F5 coagulation factor V (proaccelerin, labile factor) 2.26934
NECAP2 NECAP endocytosis associated 2 2.26906
AMZ2 archaelysin family metallopeptidase 2 2.26649
NECTIN2 nectin cell adhesion molecule 2 2.26437
SLC75A1 solute carrier family 75 member 1 2.26121
PERP PERP, TP53 apoptosis effector 2.2541
RIOK3 RIO kinase 3 2.25217
CLEC16A C-type lectin domain family 16, member A 2.25154
MYL12B myosin, light chain 12B, regulatory 2.24848
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 2.24698
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.24515
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.24501
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.24416
TBK1 TANK-binding kinase 1 2.24263
PAOX polyamine oxidase (exo-N4-amino) 2.23998
TMEM9B TMEM9 domain family, member B 2.23323
SUN2 Sad1 and UNC84 domain containing 2 2.22991
PRDX1 peroxiredoxin 1 2.22954
CLIP1 CAP-GLY domain containing linker protein 1 2.22928
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 2.2265
KDM6B lysine (K)-specific demethylase 6B 2.22316
BCL2L1 BCL2-like 1 2.22085
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 2.21876
SLC67A1 solute carrier family 67 member 1 2.21655
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.21624
SOX9 SRY (sex determining region Y)-box 9 2.21609
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.21523
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.21261
ATG4A autophagy related 4A, cysteine peptidase 2.21058
PDGFC platelet derived growth factor C 2.20785
TMEM134 transmembrane protein 134 2.20748
VAMP8 vesicle-associated membrane protein 8 2.20602
ZDHHC18 zinc finger, DHHC-type containing 18 2.2056
CLBA1 clathrin binding box of aftiphilin containing 1 2.19924
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.19128
ZMPSTE24 zinc metallopeptidase STE24 2.19055
MBNL2 muscleblind-like splicing regulator 2 2.18856
BAZ2B bromodomain adjacent to zinc finger domain, 2B 2.18666
GBP2 guanylate binding protein 2, interferon-inducible 2.18414
EGLN2 egl-9 family hypoxia-inducible factor 2 2.18367
WASHC3 WASH complex subunit 3 2.17986
RAB1A RAB1A, member RAS oncogene family 2.17346
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.17247
SLC10A3 solute carrier family 10, member 3 2.1683
SYNRG synergin, gamma 2.16807
LTBP3 latent transforming growth factor beta binding protein 3 2.16689
BLVRA biliverdin reductase A 2.16521
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.16442
CAMTA2 calmodulin binding transcription activator 2 2.16426
ATF3 activating transcription factor 3 2.16372
PDCD6IP programmed cell death 6 interacting protein 2.16215
ARHGAP12 Rho GTPase activating protein 12 2.16182
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.15913
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.15555
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 2.15485
NPPA natriuretic peptide A 2.15044
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.15035
TMEM59 transmembrane protein 59 2.14661
UBA1 ubiquitin-like modifier activating enzyme 1 2.1461
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.14382
USP33 ubiquitin specific peptidase 33 2.14327
MINK1 misshapen-like kinase 1 2.14308
GRN granulin 2.14161
SURF2 surfeit 2 2.13609
SFTPA2 surfactant protein A2 2.13583
STXBP2 syntaxin binding protein 2 2.13442
GADD45A growth arrest and DNA-damage-inducible, alpha 2.13365
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.13201
MINDY1 MINDY lysine 48 deubiquitinase 1 2.13147
KLC3 kinesin light chain 3 2.13084
ZFHX3 zinc finger homeobox 3 2.13015
COL17A1 collagen, type XVII, alpha 1 2.12745
NIT1 nitrilase 1 2.12717
CD151 CD151 molecule (Raph blood group) 2.12655
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.12651
ETFB electron-transfer-flavoprotein, beta polypeptide 2.12433
PVR poliovirus receptor 2.12388
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.12276
YPEL5 yippee-like 5 (Drosophila) 2.11758
CTSB cathepsin B 2.11302
MXRA7 matrix-remodelling associated 7 2.11194
IL18 interleukin 18 2.11144
ATG9A autophagy related 9A 2.10768
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.10653
RRAGC Ras-related GTP binding C 2.10553
CLCNKA chloride channel, voltage-sensitive Ka 2.10451
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.10038
TESK1 testis-specific kinase 1 2.10035
GPN2 GPN-loop GTPase 2 2.09841
RWDD2B RWD domain containing 2B 2.09459
ADGRG1 adhesion G protein-coupled receptor G1 2.09451
NMT1 N-myristoyltransferase 1 2.09417
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.09257
LAMC2 laminin, gamma 2 2.08834
TLR4 toll-like receptor 4 2.08437
CDR2L cerebellar degeneration-related protein 2-like 2.08161
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.07241
NCF2 neutrophil cytosolic factor 2 2.07241
SLC35F6 solute carrier family 35, member F6 2.07094
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.06918
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.06909
PLEK2 pleckstrin 2 2.06822
TCF15 transcription factor 15 (basic helix-loop-helix) 2.06245
IL11 interleukin 11 2.06192
GDI1 GDP dissociation inhibitor 1 2.06186
CSK c-src tyrosine kinase 2.05986
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.05965
PHF1 PHD finger protein 1 2.05824
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.05619
LSP1 lymphocyte-specific protein 1 2.0556
SMAD3 SMAD family member 3 2.05535
CLDN4 claudin 4 2.05394
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 2.0533
ANXA3 annexin A3 2.05223
STK17A serine/threonine kinase 17a 2.0516
WDR1 WD repeat domain 1 2.05133
ZNF219 zinc finger protein 219 2.05024
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 2.0498
DLX5 distal-less homeobox 5 2.04859
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.04706
INO80B INO80 complex subunit B 2.0435
MAP2K3 mitogen-activated protein kinase kinase 3 2.04189
ITFG1 integrin alpha FG-GAP repeat containing 1 2.04076
BBS1 Bardet-Biedl syndrome 1 2.04062
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 2.03955
TRADD TNFRSF1A-associated via death domain 2.0375
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.03518
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.03504
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.03174
TOB1 transducer of ERBB2, 1 2.03147
PRCP prolylcarboxypeptidase (angiotensinase C) 2.03073
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.03051
ADGRD2 adhesion G protein-coupled receptor D2 2.03005
TBC1D22A TBC1 domain family, member 22A 2.02901
ELL2 elongation factor, RNA polymerase II, 2 2.02733
FOXO1 forkhead box O1 2.02131
WDR44 WD repeat domain 44 2.01883
JAK1 Janus kinase 1 2.01784
TLN1 talin 1 2.01347
HDAC7 histone deacetylase 7 2.00614

decreased expression

Symbol Name Standardized Value
MCM3 minichromosome maintenance complex component 3 -6.88582
RPS4Y1 ribosomal protein S4, Y-linked 1 -6.80358
MCM6 minichromosome maintenance complex component 6 -6.03145
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -6.02213
KIF15 kinesin family member 15 -5.83421
KIF20A kinesin family member 20A -5.82414
PGM1 phosphoglucomutase 1 -5.64159
KIF4A kinesin family member 4A -5.62014
NUP85 nucleoporin 85kDa -5.50902
UBE2C ubiquitin-conjugating enzyme E2C -5.44645
LBR lamin B receptor -5.30316
CDT1 chromatin licensing and DNA replication factor 1 -5.21399
NLRP4 NLR family, pyrin domain containing 4 -5.15619
CCNA2 cyclin A2 -5.04742
ELOVL6 ELOVL fatty acid elongase 6 -4.83633
BIRC5 baculoviral IAP repeat containing 5 -4.807
AURKB aurora kinase B -4.78855
SPC25 SPC25, NDC80 kinetochore complex component -4.75476
STMN1 stathmin 1 -4.74859
PLK1 polo-like kinase 1 -4.68193
CDC20 cell division cycle 20 -4.61817
OIP5 Opa interacting protein 5 -4.59059
DIPK1A divergent protein kinase domain 1A -4.5467
HMGB2 high mobility group box 2 -4.53273
CCNB2 cyclin B2 -4.49102
RFC4 replication factor C (activator 1) 4, 37kDa -4.48607
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.46851
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.40322
GINS1 GINS complex subunit 1 (Psf1 homolog) -4.38341
MCM4 minichromosome maintenance complex component 4 -4.36062
PSRC1 proline/serine-rich coiled-coil 1 -4.35582
CENPE centromere protein E, 312kDa -4.35568
MCM7 minichromosome maintenance complex component 7 -4.3292
ARHGAP11A Rho GTPase activating protein 11A -4.30519
CDC45 cell division cycle 45 -4.30413
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.29644
PROM1 prominin 1 -4.28306
DSCC1 DNA replication and sister chromatid cohesion 1 -4.25835
TRMT5 tRNA methyltransferase 5 -4.23735
ENOPH1 enolase-phosphatase 1 -4.16247
MCM5 minichromosome maintenance complex component 5 -4.1355
TMEM97 transmembrane protein 97 -4.11779
LMNB1 lamin B1 -4.10494
GGCT gamma-glutamylcyclotransferase -4.0723
CDC6 cell division cycle 6 -4.05029
SPAG5 sperm associated antigen 5 -4.04602
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.04338
NUSAP1 nucleolar and spindle associated protein 1 -4.01639
ERCC6L excision repair cross-complementation group 6-like -4.01286
VRK1 vaccinia related kinase 1 -4.012
CDK1 cyclin-dependent kinase 1 -3.9976
MIS18A MIS18 kinetochore protein A -3.99563
FEN1 flap structure-specific endonuclease 1 -3.98196
EXO1 exonuclease 1 -3.96599
MCM10 minichromosome maintenance complex component 10 -3.96291
WDR76 WD repeat domain 76 -3.95904
FBL fibrillarin -3.91843
PUF60 poly-U binding splicing factor 60KDa -3.89173
NDC80 NDC80 kinetochore complex component -3.86198
HMGN2 high mobility group nucleosomal binding domain 2 -3.84443
CDC25C cell division cycle 25C -3.84071
TOP2A topoisomerase (DNA) II alpha 170kDa -3.8277
DEPDC1 DEP domain containing 1 -3.82747
FBXO5 F-box protein 5 -3.8223
PRC1 protein regulator of cytokinesis 1 -3.8123
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.80912
CENPQ centromere protein Q -3.80285
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.80084
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.76041
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.74844
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.7376
NCAPG2 non-SMC condensin II complex, subunit G2 -3.73091
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.70395
MSH2 mutS homolog 2 -3.6936
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.6706
PLK4 polo-like kinase 4 -3.65671
TK1 thymidine kinase 1, soluble -3.65634
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.61203
ZNF16 zinc finger protein 16 -3.61091
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.60356
NEK2 NIMA-related kinase 2 -3.58894
TRIP13 thyroid hormone receptor interactor 13 -3.5878
DHFR dihydrofolate reductase -3.57515
HJURP Holliday junction recognition protein -3.57047
CCNB1 cyclin B1 -3.57043
PIMREG PICALM interacting mitotic regulator -3.56167
USP1 ubiquitin specific peptidase 1 -3.54837
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.54807
TPX2 TPX2, microtubule-associated -3.53013
L1TD1 LINE-1 type transposase domain containing 1 -3.52936
PPIH peptidylprolyl isomerase H (cyclophilin H) -3.51706
E2F8 E2F transcription factor 8 -3.49844
ALDOC aldolase C, fructose-bisphosphate -3.49428
RFC3 replication factor C (activator 1) 3, 38kDa -3.49022
CDK2 cyclin-dependent kinase 2 -3.47877
ASF1B anti-silencing function 1B histone chaperone -3.47685
CDC7 cell division cycle 7 -3.46703
NT5DC2 5'-nucleotidase domain containing 2 -3.44383
KIF11 kinesin family member 11 -3.43858
NUP205 nucleoporin 205kDa -3.43369
FANCI Fanconi anemia, complementation group I -3.4257
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -3.42565
PSIP1 PC4 and SFRS1 interacting protein 1 -3.41043
HAT1 histone acetyltransferase 1 -3.40476
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -3.39762
TOPBP1 topoisomerase (DNA) II binding protein 1 -3.37864
LOC124907782 dual specificity protein phosphatase 22 -3.37475
RPUSD2 RNA pseudouridylate synthase domain containing 2 -3.37377
TF transferrin -3.36578
MANEA mannosidase, endo-alpha -3.35281
FOXM1 forkhead box M1 -3.34345
RRM2 ribonucleotide reductase M2 -3.34081
CCNF cyclin F -3.33872
SKA1 spindle and kinetochore associated complex subunit 1 -3.3354
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.33376
NASP nuclear autoantigenic sperm protein (histone-binding) -3.32537
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -3.31317
HEATR1 HEAT repeat containing 1 -3.29669
SNRPA small nuclear ribonucleoprotein polypeptide A -3.29177
ZWINT ZW10 interacting kinetochore protein -3.27848
CRIPTO3 cripto, EGF-CFC family member 3 -3.27434
TEDC2 tubulin epsilon and delta complex 2 -3.27271
CDCA3 cell division cycle associated 3 -3.26686
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.25711
NCAPD2 non-SMC condensin I complex, subunit D2 -3.24956
CENPA centromere protein A -3.24353
NUP155 nucleoporin 155kDa -3.23001
MSH6 mutS homolog 6 -3.22509
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -3.22485
RFC2 replication factor C (activator 1) 2, 40kDa -3.21858
CSE1L CSE1 chromosome segregation 1-like (yeast) -3.21487
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.21233
CDC23 cell division cycle 23 -3.20702
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.20369
NCAPH non-SMC condensin I complex, subunit H -3.19719
TMPO thymopoietin -3.19501
BRCA1 breast cancer 1, early onset -3.18964
PBK PDZ binding kinase -3.18909
PLIN2 perilipin 2 -3.18467
TMEM267 transmembrane protein 267 -3.17917
UXT ubiquitously-expressed, prefoldin-like chaperone -3.17633
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.17311
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.15795
KIFC1 kinesin family member C1 -3.15737
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -3.15476
RPA3 replication protein A3, 14kDa -3.15128
KIF18A kinesin family member 18A -3.14899
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.13722
KIF22 kinesin family member 22 -3.13645
PARPBP PARP1 binding protein -3.13569
E2F1 E2F transcription factor 1 -3.12094
CENPI centromere protein I -3.11467
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.11443
HADH hydroxyacyl-CoA dehydrogenase -3.10941
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -3.10045
TIPIN TIMELESS interacting protein -3.09757
PECR peroxisomal trans-2-enoyl-CoA reductase -3.09698
C2CD5 C2 calcium-dependent domain containing 5 -3.06389
RAD51AP1 RAD51 associated protein 1 -3.05843
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -3.05244
BORA bora, aurora kinase A activator -3.05193
DUT deoxyuridine triphosphatase -3.04572
NCAM2 neural cell adhesion molecule 2 -3.04413
HMGA2 high mobility group AT-hook 2 -3.02889
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -3.02684
ATAD2 ATPase family, AAA domain containing 2 -2.99617
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.99434
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.99027
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.98322
TCERG1 transcription elongation regulator 1 -2.98242
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.97866
H2AZ2 H2A.Z variant histone 2 -2.97839
VAV3 vav 3 guanine nucleotide exchange factor -2.97711
AUNIP aurora kinase A and ninein interacting protein -2.95824
DSN1 DSN1, MIS12 kinetochore complex component -2.95713
KIF18B kinesin family member 18B -2.95321
NOL9 nucleolar protein 9 -2.94972
MNS1 meiosis-specific nuclear structural 1 -2.94938
MKI67 marker of proliferation Ki-67 -2.94868
SMC3 structural maintenance of chromosomes 3 -2.94625
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -2.94359
DBF4 DBF4 zinc finger -2.93867
CFAP20 cilia and flagella associated protein 20 -2.93572
FANCC Fanconi anemia, complementation group C -2.93248
MAK16 MAK16 homolog (S. cerevisiae) -2.93151
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.92911
H2AZ1 H2A.Z variant histone 1 -2.92607
PRIM1 primase, DNA, polypeptide 1 (49kDa) -2.90316
SELENBP1 selenium binding protein 1 -2.90032
GALP galanin-like peptide -2.89813
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.89507
RANBP1 RAN binding protein 1 -2.89492
IFITM1 interferon induced transmembrane protein 1 -2.88847
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -2.88602
CENPS-CORT CENPS-CORT readthrough -2.88323
SEPHS1 selenophosphate synthetase 1 -2.88293
MTERF3 mitochondrial transcription termination factor 3 -2.88205
TEAD4 TEA domain family member 4 -2.87255
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.87176
NDC1 NDC1 transmembrane nucleoporin -2.86371
CASP8AP2 caspase 8 associated protein 2 -2.86234
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -2.85513
ZNF107 zinc finger protein 107 -2.8547
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.84906
BRIX1 BRX1, biogenesis of ribosomes -2.83562
NANOG Nanog homeobox -2.82838
HAS2 hyaluronan synthase 2 -2.82799
IFITM2 interferon induced transmembrane protein 2 -2.82724
KIF14 kinesin family member 14 -2.81767
PMP2 peripheral myelin protein 2 -2.81087
PUS1 pseudouridylate synthase 1 -2.80398
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.80001
MIS18BP1 MIS18 binding protein 1 -2.79981
NUP54 nucleoporin 54kDa -2.79859
CNTNAP2 contactin associated protein-like 2 -2.78469
NCAPD3 non-SMC condensin II complex, subunit D3 -2.7789
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.77786
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.77334
DPPA4 developmental pluripotency associated 4 -2.77292
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.76675
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.75769
RFXAP regulatory factor X-associated protein -2.75696
PLP1 proteolipid protein 1 -2.75636
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.75393
FANCG Fanconi anemia, complementation group G -2.75299
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.75245
THEM6 thioesterase superfamily member 6 -2.75221
POLK polymerase (DNA directed) kappa -2.74551
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.74425
HELLS helicase, lymphoid-specific -2.74344
FAR2 fatty acyl CoA reductase 2 -2.73512
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.73366
SRD5A3 steroid 5 alpha-reductase 3 -2.7326
RAD51 RAD51 recombinase -2.72598
ATAD5 ATPase family, AAA domain containing 5 -2.71802
CER1 cerberus 1, DAN family BMP antagonist -2.71345
ANAPC1 anaphase promoting complex subunit 1 -2.71297
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.70462
BARD1 BRCA1 associated RING domain 1 -2.69733
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.69691
H2AX H2A.X variant histone -2.69535
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.69533
USP39 ubiquitin specific peptidase 39 -2.68814
SIDT1 SID1 transmembrane family, member 1 -2.6835
IFITM3 interferon induced transmembrane protein 3 -2.68244
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.68146
ADD3 adducin 3 (gamma) -2.68019
HMGN1 high mobility group nucleosome binding domain 1 -2.67502
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.67178
NID2 nidogen 2 (osteonidogen) -2.66827
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.66723
GPR19 G protein-coupled receptor 19 -2.66696
NFYB nuclear transcription factor Y, beta -2.66398
THY1 Thy-1 cell surface antigen -2.66
FOXN2 forkhead box N2 -2.65915
RAD54B RAD54 homolog B (S. cerevisiae) -2.65753
MCMBP minichromosome maintenance complex binding protein -2.65476
COL3A1 collagen, type III, alpha 1 -2.65407
KIF23 kinesin family member 23 -2.65217
ZBTB14 zinc finger and BTB domain containing 14 -2.64672
PRPF6 pre-mRNA processing factor 6 -2.64425
EPCIP exosomal polycystin 1 interacting protein -2.64286
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.63466
MDM4 MDM4, p53 regulator -2.63169
SCN1A sodium channel, voltage gated, type I alpha subunit -2.63108
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.61798
MPHOSPH9 M-phase phosphoprotein 9 -2.61772
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.61683
LIN28A lin-28 homolog A (C. elegans) -2.61659
KNTC1 kinetochore associated 1 -2.61553
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.60922
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.60665
RRM1 ribonucleotide reductase M1 -2.60545
CEP57 centrosomal protein 57kDa -2.60145
CERS1 ceramide synthase 1 -2.59505
IPO5 importin 5 -2.58774
ZIC3 Zic family member 3 -2.58509
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.58499
CXCL5 chemokine (C-X-C motif) ligand 5 -2.58422
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.5842
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.58352
GPHN gephyrin -2.5738
CBX5 chromobox homolog 5 -2.57071
CDK7 cyclin-dependent kinase 7 -2.56772
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.56431
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.56084
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -2.55574
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.55335
DONSON downstream neighbor of SON -2.55224
RGS7 regulator of G-protein signaling 7 -2.55075
CENPU centromere protein U -2.54868
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.54839
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.54695
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.54533
TTK TTK protein kinase -2.54468
NREP neuronal regeneration related protein -2.54204
IL17RB interleukin 17 receptor B -2.53953
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.53837
ADGRG2 adhesion G protein-coupled receptor G2 -2.53778
XYLT1 xylosyltransferase I -2.536
UNG uracil-DNA glycosylase -2.53293
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.52795
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like -2.52514
E2F5 E2F transcription factor 5, p130-binding -2.52215
ITM2C integral membrane protein 2C -2.52147
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.50556
VASH2 vasohibin 2 -2.50459
HSPA14 heat shock 70kDa protein 14 -2.50369
TP53 tumor protein p53 -2.50161
DCT dopachrome tautomerase -2.49999
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.49604
DPP6 dipeptidyl-peptidase 6 -2.49229
PEX11A peroxisomal biogenesis factor 11 alpha -2.48182
TFRC transferrin receptor -2.4701
CAMTA1 calmodulin binding transcription activator 1 -2.46713
BLMH bleomycin hydrolase -2.46648
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -2.4661
PYCR1 pyrroline-5-carboxylate reductase 1 -2.46603
VCAM1 vascular cell adhesion molecule 1 -2.46499
DCK deoxycytidine kinase -2.46312
TYRP1 tyrosinase-related protein 1 -2.4583
EIF3K eukaryotic translation initiation factor 3, subunit K -2.45476
PRKCB protein kinase C, beta -2.45242
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.45022
NLGN4Y neuroligin 4, Y-linked -2.4494
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.44589
RUBCNL rubicon like autophagy enhancer -2.43899
ANAPC15 anaphase promoting complex subunit 15 -2.43297
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -2.43152
CDC25A cell division cycle 25A -2.43071
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.43008
CD53 CD53 molecule -2.42832
BHMT betaine--homocysteine S-methyltransferase -2.4244
MYO10 myosin X -2.42379
NUP93 nucleoporin 93kDa -2.4178
RCAN3 RCAN family member 3 -2.41763
FABP7 fatty acid binding protein 7, brain -2.41568
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -2.41185
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.41151
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.40489
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.40216
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.40153
MYEF2 myelin expression factor 2 -2.40083
SSRP1 structure specific recognition protein 1 -2.39958
AQP4 aquaporin 4 -2.39858
SOAT2 sterol O-acyltransferase 2 -2.39739
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.39456
NOX1 NADPH oxidase 1 -2.39207
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.39009
PDE4B phosphodiesterase 4B, cAMP-specific -2.38749
ASS1 argininosuccinate synthase 1 -2.38724
CXADR coxsackie virus and adenovirus receptor -2.38686
ATP11B ATPase, class VI, type 11B -2.38614
RNFT2 ring finger protein, transmembrane 2 -2.38438
ADGRL1 adhesion G protein-coupled receptor L1 -2.38402
AZIN1 antizyme inhibitor 1 -2.38276
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.38165
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.3813
EXOSC8 exosome component 8 -2.38003
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.37784
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.37761
CENPF centromere protein F, 350/400kDa -2.37552
ZNF696 zinc finger protein 696 -2.3721
GAS2 growth arrest-specific 2 -2.37053
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -2.36629
NUCB2 nucleobindin 2 -2.36528
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.3652
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.36335
NCKIPSD NCK interacting protein with SH3 domain -2.36214
EPYC epiphycan -2.3596
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.35642
CXCL6 chemokine (C-X-C motif) ligand 6 -2.35494
MRPL16 mitochondrial ribosomal protein L16 -2.35427
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.35243
SATB2 SATB homeobox 2 -2.35033
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.34976
U2SURP U2 snRNP-associated SURP domain containing -2.3489
RBL1 retinoblastoma-like 1 -2.34343
GFOD1 glucose-fructose oxidoreductase domain containing 1 -2.34146
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -2.33657
PEX5L peroxisomal biogenesis factor 5-like -2.33583
POLR1F RNA polymerase I subunit F -2.3349
ZNF7 zinc finger protein 7 -2.33381
SIVA1 SIVA1, apoptosis-inducing factor -2.33021
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.32993
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.32838
PLEKHS1 pleckstrin homology domain containing, family S member 1 -2.32338
APOH apolipoprotein H (beta-2-glycoprotein I) -2.31885
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.31688
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.31649
HOXB9 homeobox B9 -2.31556
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.31338
QSER1 glutamine and serine rich 1 -2.31034
LIAS lipoic acid synthetase -2.30913
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -2.3064
XPO7 exportin 7 -2.30275
MMP13 matrix metallopeptidase 13 -2.30218
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.29841
CHL1 cell adhesion molecule L1-like -2.29599
DOK5 docking protein 5 -2.29224
POU4F2 POU class 4 homeobox 2 -2.29124
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.28975
MRPS27 mitochondrial ribosomal protein S27 -2.28683
CXCL3 chemokine (C-X-C motif) ligand 3 -2.28551
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.28475
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.28433
RFWD3 ring finger and WD repeat domain 3 -2.28338
ZNF623 zinc finger protein 623 -2.28268
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.27508
MRPL11 mitochondrial ribosomal protein L11 -2.2744
GMEB2 glucocorticoid modulatory element binding protein 2 -2.27398
GAP43 growth associated protein 43 -2.27246
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -2.272
CEP192 centrosomal protein 192kDa -2.2705
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.26768
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -2.26488
CFHR2 complement factor H-related 2 -2.26154
PYCR3 pyrroline-5-carboxylate reductase 3 -2.26047
THOC1 THO complex 1 -2.2588
TROAP trophinin associated protein -2.25865
HMGN5 high mobility group nucleosome binding domain 5 -2.25805
HSPA13 heat shock protein 70kDa family, member 13 -2.25249
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.25077
SRSF3 serine/arginine-rich splicing factor 3 -2.24658
RPIA ribose 5-phosphate isomerase A -2.24427
EIF3E eukaryotic translation initiation factor 3, subunit E -2.24012
CBX3 chromobox homolog 3 -2.23984
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.2398
RAD21 RAD21 homolog (S. pombe) -2.23698
CHEK2 checkpoint kinase 2 -2.23683
OXCT1 3-oxoacid CoA transferase 1 -2.23618
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -2.23519
CA14 carbonic anhydrase XIV -2.23364
SQLE squalene epoxidase -2.23186
ZNF587B zinc finger protein 587B -2.23149
LIN9 lin-9 DREAM MuvB core complex component -2.22656
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.22626
CETN3 centrin, EF-hand protein, 3 -2.22624
NKX3-2 NK3 homeobox 2 -2.22565
WBP11 WW domain binding protein 11 -2.22553
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.22518
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.2195
SKI SKI proto-oncogene -2.21542
FZD7 frizzled class receptor 7 -2.21509
EXOSC9 exosome component 9 -2.21344
PGAP2 post-GPI attachment to proteins 2 -2.21283
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -2.21184
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.21156
ZNF302 zinc finger protein 302 -2.21105
HPR haptoglobin-related protein -2.21025
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.20719
AGO2 argonaute RISC catalytic component 2 -2.20717
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.20626
CDCA4 cell division cycle associated 4 -2.20475
ATP10B ATPase, class V, type 10B -2.20412
FBF1 Fas (TNFRSF6) binding factor 1 -2.20307
ZNF552 zinc finger protein 552 -2.2029
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.20267
QARS1 glutaminyl-tRNA synthetase 1 -2.20185
TCP1 t-complex 1 -2.20115
KLF13 Kruppel-like factor 13 -2.18909
NTAQ1 N-terminal glutamine amidase 1 -2.18839
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -2.18732
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.18732
TARDBP TAR DNA binding protein -2.18725
FFAR2 free fatty acid receptor 2 -2.18632
MATR3 matrin 3 -2.18505
POLR1G RNA polymerase I subunit G -2.18347
HMGB1 high mobility group box 1 -2.17389
SDF2L1 stromal cell-derived factor 2-like 1 -2.17301
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -2.17301
STIL SCL/TAL1 interrupting locus -2.17233
PSAT1 phosphoserine aminotransferase 1 -2.17224
RAB26 RAB26, member RAS oncogene family -2.17171
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -2.17132
LPAR4 lysophosphatidic acid receptor 4 -2.16972
ZNF286A zinc finger protein 286A -2.16939
THAP9 THAP domain containing 9 -2.16757
MELK maternal embryonic leucine zipper kinase -2.16737
SEPTIN7 septin 7 -2.16596
ZBTB35 zinc finger and BTB domain containing 35 -2.16478
SLC2A4RG SLC2A4 regulator -2.16326
ZNF83 zinc finger protein 83 -2.16285
UBA2 ubiquitin-like modifier activating enzyme 2 -2.16206
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.16008
CLEC11A C-type lectin domain family 11, member A -2.15904
MLANA melan-A -2.15894
MLEC malectin -2.15747
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 -2.15597
MAGOHB mago-nashi homolog B (Drosophila) -2.15534
PTTG1 pituitary tumor-transforming 1 -2.155
ADH6 alcohol dehydrogenase 6 (class V) -2.15111
AMPH amphiphysin -2.15067
CALB1 calbindin 1, 28kDa -2.14944
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.14854
SNRPE small nuclear ribonucleoprotein polypeptide E -2.14325
LSAMP limbic system-associated membrane protein -2.1404
POMK protein-O-mannose kinase -2.14019
CTNND2 catenin (cadherin-associated protein), delta 2 -2.13983
ELP4 elongator acetyltransferase complex subunit 4 -2.13822
LIME1 Lck interacting transmembrane adaptor 1 -2.13807
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -2.13713
FAF1 Fas (TNFRSF6) associated factor 1 -2.1351
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.13367
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.13363
RACGAP1 Rac GTPase activating protein 1 -2.1248
IL2 interleukin 2 -2.12451
RBM12 RNA binding motif protein 12 -2.12212
ABI3BP ABI family, member 3 (NESH) binding protein -2.12105
NRF1 nuclear respiratory factor 1 -2.12007
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -2.11914
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.11856
RAD54L RAD54-like (S. cerevisiae) -2.11533
SNRPF small nuclear ribonucleoprotein polypeptide F -2.11514
DTWD1 DTW domain containing 1 -2.11509
STK17B serine/threonine kinase 17b -2.11286
TMEM243 transmembrane protein 243, mitochondrial -2.11232
MAGEB4 melanoma antigen family B4 -2.11113
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.1101
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.11009
PDIA6 protein disulfide isomerase family A, member 6 -2.10735
RAB15 RAB15, member RAS oncogene family -2.10558
PHGDH phosphoglycerate dehydrogenase -2.10525
SRP72 signal recognition particle 72kDa -2.10501
MCTP2 multiple C2 domains, transmembrane 2 -2.10181
COL1A2 collagen, type I, alpha 2 -2.10124
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -2.10123
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.09997
AKR1D1 aldo-keto reductase family 1, member D1 -2.09792
JRK Jrk homolog (mouse) -2.09741
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.09652
TMEM183A transmembrane protein 183A -2.09424
RHOH ras homolog family member H -2.09301
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -2.09192
GYG2 glycogenin 2 -2.0919
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.09087
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -2.08999
MAGED4B melanoma antigen family D4B -2.08995
RIT2 Ras-like without CAAX 2 -2.08925
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.08883
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.08813
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -2.08405
CHEK1 checkpoint kinase 1 -2.08289
MYB v-myb avian myeloblastosis viral oncogene homolog -2.08112
MSMO1 methylsterol monooxygenase 1 -2.08092
EDAR ectodysplasin A receptor -2.07911
PFAS phosphoribosylformylglycinamidine synthase -2.07505
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.07136
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.07132
NUP62 nucleoporin 62kDa -2.0709
SFXN1 sideroflexin 1 -2.06911
ZNF675 zinc finger protein 675 -2.06755
ZNF273 zinc finger protein 273 -2.06752
SEC14L5 SEC14-like 5 (S. cerevisiae) -2.0646
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.06332
TEX30 testis expressed 30 -2.06327
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.06325
PCLAF PCNA clamp associated factor -2.06124
FMO3 flavin containing monooxygenase 3 -2.0598
SPRY4 sprouty homolog 4 (Drosophila) -2.05908
GRHL2 grainyhead-like 2 (Drosophila) -2.05903
CENPN centromere protein N -2.05827
FGF1 fibroblast growth factor 1 (acidic) -2.05648
NUP107 nucleoporin 107kDa -2.05639
MAN1C1 mannosidase, alpha, class 1C, member 1 -2.05595
ZNF22 zinc finger protein 22 -2.05558
SNTG1 syntrophin, gamma 1 -2.05442
LGI1 leucine-rich, glioma inactivated 1 -2.05312
CDK4 cyclin-dependent kinase 4 -2.05218
CLMN calmin (calponin-like, transmembrane) -2.04925
POU5F1 POU class 5 homeobox 1 -2.04833
ZNF239 zinc finger protein 239 -2.04779
COL5A3 collagen, type V, alpha 3 -2.04677
GID8 GID complex subunit 8 -2.04656
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.04627
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.04464
FANCA Fanconi anemia, complementation group A -2.04436
CD5L CD5 molecule-like -2.0433
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.04308
RPH3A rabphilin 3A -2.04295
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 -2.04217
CALM1 calmodulin 1 (phosphorylase kinase, delta) -2.04087
SERHL2 serine hydrolase-like 2 -2.0391
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.03853
SP4 Sp4 transcription factor -2.0362
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.03568
CFHR5 complement factor H-related 5 -2.03427
MTF2 metal response element binding transcription factor 2 -2.03415
CEP83 centrosomal protein 83kDa -2.03408
IL7 interleukin 7 -2.03383
CPB2 carboxypeptidase B2 (plasma) -2.03151
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 -2.02946
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -2.02899
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -2.02888
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.02803
CYB5RL cytochrome b5 reductase-like -2.02738
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.02557
EMC2 ER membrane protein complex subunit 2 -2.02413
FKTN fukutin -2.02092
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.02082
COL9A1 collagen, type IX, alpha 1 -2.01919
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -2.01869
COPZ1 coatomer protein complex, subunit zeta 1 -2.01866
CBLN1 cerebellin 1 precursor -2.01756
RTN3 reticulon 3 -2.01612
TMEM254 transmembrane protein 254 -2.0155
ZNF215 zinc finger protein 215 -2.0151
ZMYM1 zinc finger, MYM-type 1 -2.01508
APLNR apelin receptor -2.01156
GPA33 glycoprotein A33 (transmembrane) -2.01096
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.0098
URI1 URI1, prefoldin-like chaperone -2.00879
GUSB glucuronidase, beta -2.00684
APOA2 apolipoprotein A-II -2.00321
DEFB126 defensin, beta 126 -2.00256